A practical computer-based approach to the analysis of radioligand binding experiments

Computer Programs in Biomedicine - Tập 17 Số 1-2 - Trang 107-113 - 1983
Grant A. McPherson1
1University of Melbourne, Clinical Pharmacology and Therapeutics Unit, Austin Hospital, Heidelberg, Vic., 3084, Australia

Tóm tắt

Từ khóa


Tài liệu tham khảo

Scatchard, 1949, The attractions of protein for small molecules and ions, Ann. NY Acad. Sci., 52, 660, 10.1111/j.1749-6632.1949.tb27297.x

Norby, 1980, Scatchard plot: Common misinterpretation of binding estimates, Anal. Biochem., 102, 318, 10.1016/0003-2697(80)90160-8

Thakur, 1980, Characterization of ligand binding systems by continuous affinity distribution of arbitrary shape, Anal. Biochem., 103, 240, 10.1016/0003-2697(80)90263-8

Williams, 1978

Munson, 1980, LIGAND: A versatile computerized approach for characterization of ligand binding systems, Anal. Biochem., 107, 220, 10.1016/0003-2697(80)90515-1

Cheng, 1973, Relationship between the inhibition constant (Ki) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction, Biochem. Pharmacol., 22, 3099, 10.1016/0006-2952(73)90196-2

Parker, 1971, Pharmacological estimation of drug receptor dissociation constants. Statistical evaluation: 1. Agonists, J. Pharmacol. Exp. Ther., 177, 1

Molinoff, 1981, Quantitative analysis of drug receptor interactions: II Determination of the properties of receptor subtypes, Life Sci., 29, 427, 10.1016/0024-3205(81)90208-3