A possible model of benzimidazole binding to β-tubulin disclosed by invoking an inter-domain movement
Tóm tắt
Từ khóa
Tài liệu tham khảo
Lacey, 1988, The role of the cytoskeletal protein, tubulin, in the mode of action and mechanism of drug resistance to benzimidazoles, Int. J. Parasitol., 18, 885, 10.1016/0020-7519(88)90175-0
Lubega, 1990, Specific interaction of benzimadazole anthelmintics with tubulin: high-affinity binding and benzimidazole resistance in Haemonchus contortus, Mol. Biochem. Parasitol., 38, 221, 10.1016/0166-6851(90)90025-H
Prichard, 2001, Genetic variability following selection of Haemonchus contortus with anthelmintics, Trends Parasitol., 17, 445, 10.1016/S1471-4922(01)01983-3
Robinson, 2002, Benzimidazole binding to Haemonchus contortus tubulin: a question of structure, Trends Parasitol., 18, 153, 10.1016/S1471-4922(01)02225-5
Kwa, 1994, Benzimadazole resistance in Haemonchus contortus is correlated with a conserved mutation at amino acid 200 in β-tubulin isotype 1, Mol. Biochem. Parasitol., 63, 299, 10.1016/0166-6851(94)90066-3
Silvestre, 2002, Mutation in position 167 of isotype-I β-tubulin gene of Trichostrongylid nematodes: roles in benzimidazole resistance?, Mol. Biochem. Parasitol., 120, 297, 10.1016/S0166-6851(01)00455-8
Nare, 1996, p-Azidosalicyl-5-amino-6-phenoxybenzimidazole photolabels the N-terminal 63–103 amino acids of Haemonchus contortus β-tubulin 1, J. Biol. Chem., 271, 8575, 10.1074/jbc.271.15.8575
Downing, 2000, Structural basis for the action of drugs that affect microtubule dynamics, Emerg. Ther. Targets, 4, 219, 10.1517/14728222.4.2.219
Nogales, 1998, Structure of the αβ-tubulin dimer by electron crystallography, Nature, 391, 199, 10.1038/34465
Jung, 1990, Identification of an amino acid substitution in the benA β-tubulin gene of Aspergillus nidulans that confers thiabendazole resistance and benomyl supersensitivity, Cell Motil. Cytoskeleton, 17, 87, 10.1002/cm.970170204
Jung, 1992, Amino acid alterations in the benA (β-tubulin) gene of Aspergillus nidulans that confer benomyl resistance, Cell. Motil. Cytoskeleton, 22, 170, 10.1002/cm.970220304
Li, 1996, Site-directed mutagenesis of Saccharomyces cerevisiae β-tubulin: interaction between residue 167 and benzimidazole compounds, FEBS Lett., 385, 7, 10.1016/0014-5793(96)00334-1
Nogales, 1998, Tubulin and FtsZ form a distinct family of GTPases, Nat. Struct. Biol., 5, 451, 10.1038/nsb0698-451
Amos, 1999, How Taxol® stabilises microtubule structure, Chem. Biol., 6, R65, 10.1016/S1074-5521(99)89002-4
Robinson, 2001, Characterisation of a β-tubulin gene from the liver fluke Fasciola hepatica, Int. J. Parasitol., 31, 1264, 10.1016/S0020-7519(01)00240-5
Geary, 1992, Three β-tubulin cDNAs from the parasitic nematode Haemonchus contortus, Mol. Biochem. Parasitol., 50, 295, 10.1016/0166-6851(92)90227-B
Lowe, 2001, Refined structure of αβ-tubulin at 3.5Å, J. Mol. Biol., 313
Snyder, 2001, The binding conformation of taxol in β-tubulin: a model based on electron crystallographic density, Proc. Nat. Acad. Sci. U.S.A., 98, 5312, 10.1073/pnas.051309398
Bai, 2000, Mapping the binding site of colchicinoids on β-tubulin. 2-Chloroacetyl-2-demethyliocolchicine covalently reacts predominantly with cysteine 239 and secondarily with cysteine 354, J. Biol. Chem., 275, 40443, 10.1074/jbc.M005299200
Lowe, 1998, Crystal structure of the bacterial cell division protein FtsZ, Nature, 391, 203, 10.1038/34472
Millet, 2003, The energetic cost of domain reorientation in maltose-binding protein as studied by NMR and fluorescence spectrometry, Proc. Nat. Acad. Sci. U.S.A., 100, 12700, 10.1073/pnas.2134311100
Song, 2001, Structure of a fast kinesin: implications for ATPase mechanism and interactions with microtubules, EMBO J., 20, 6213, 10.1093/emboj/20.22.6213
Buchanan, 2003, Fasciola hepatica: surface and internal tegumental changes induced by treatment in vitro with the sulphoxide metabolite of albendazole (‘Valbazen’), Parasitology, 126, 141, 10.1017/S0031182002002664
Nagano, 2003, Crystal structures of epithilone D-bound, epithilone B-bound, and substrate-free forms of cytochrome P450epoK, J. Biol. Chem., 278, 44886, 10.1074/jbc.M308115200
Lubega, 1991, Interaction of benzimidazole anthelmintics with Haemonchus contortus tubulin: binding affinity and anthelmintic efficacy, Exp. Parasitol., 73, 203, 10.1016/0014-4894(91)90023-P
Lacey, 1987, Further investigations of the primary mechanism of benzimidazole resistance in Haemonchus contortus, Int. J. Parasitol., 17, 1421, 10.1016/0020-7519(87)90077-4
Detrich, 2000, Cold adaptation of microtubule assembly and dynamics, Structural interpretation of primary sequence changes present in the α- and β-tubulins of Antarctic fishes, J. Biol. Chem., 275, 37038, 10.1074/jbc.M005699200
William, 2001, Stability and reproductive fitness of Schistosoma mansoni isolates with decreased sensitivity to praziquantel, Int. J. Parasitol., 31, 1093, 10.1016/S0020-7519(01)00215-6