A palladium–phosphine catalytic system as an active and recycable precatalyst for Suzuki coupling in water

Springer Science and Business Media LLC - Tập 40 - Trang 657-663 - 2015
Seyyed Javad Sabounchei1, Marjan Hosseinzadeh1, Mohammad Panahimehr2, Davood Nematollahi1, Hamid Reza Khavasi3, Sadegh Khazalpour1
1Faculty of Chemistry, Bu-Ali Sina University, Hamedan, Iran
2Young Researchers and Elite Club, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran
3Department of Chemistry, Shahid Beheshti University, Evin, Tehran, Iran

Tóm tắt

The Suzuki–Miyaura reaction of various aryl halides with aryl boronic acids using {[Ph2PCH2PPh2CH=C(O)(C10H7)]PdCl2} as a catalyst has been investigated. The X-ray crystal structure of the catalyst reveals a five-membered chelate ring formed by coordination of the ligand through the phosphine group and the ylidic carbon atom to the metal center. This palladacycle exhibited excellent activities and reusability in the aqueous phase for the Suzuki cross-coupling reactions of arylboronic acids with aryl halides. The proposed protocol featured mild reaction conditions and notable simplicity and efficiency using Cs2CO3 as a base in water. The catalytic system could be reused four times without significant loss of activity.

Tài liệu tham khảo

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