A novel phospholipid-binding protein from the yeast Saccharomyces cerevisiae with dual binding specificities for the transport GTPase Ypt7p and the Sec1-related Vps33p

Adams, 1997 Banta, 1990, Characterization of yeast Vps33p, a protein required for vacuolar protein sorting and vacuole biogenesis, Mol. Cell. Biol., 10, 4638 Bon, 2000, A network of proteins around Rvs167p and Rvs161p, two proteins related to the yeast actin cytoskeleton, Yeast, 16, 1229, 10.1002/1097-0061(20000930)16:13<1229::AID-YEA618>3.0.CO;2-Q De Antoni, 2000, A novel multi-purpose cassette for repeated integrative epitope-tagging of genes in Saccharomyces cerevisiae, Gene, 246, 179, 10.1016/S0378-1119(00)00083-4 Eitzen, 2001, Rho1p and Cdc42p act after Ypt7p to regulate vacuole docking, EMBO J., 20, 5650, 10.1093/emboj/20.20.5650 Foti, 2001, Sac1 lipid phosphatase and Stt4 phosphatidylinositol-4-kinase regulate a pool of phosphatidylinositol-4-phosphate that functions in the control of the actin cytoskeleton and vacuole morphology, Mol. Biol. Cell, 12, 2396, 10.1091/mbc.12.8.2396 Gerhardt, 1998, The vesicle transport protein Vps33p is an ATP-binding protein that localizes to the cytosol in an energy-dependent manner, J. Biol. Chem., 273, 15818, 10.1074/jbc.273.25.15818 Götte, 1999, The ins and outs of vacuolar trafficking, Protoplasma, 209, 9, 10.1007/BF01415696 Güldener, 1996, A new efficient gene disruption cassette for repeated use in budding yeast, Nucleic Acids Res., 24, 2519, 10.1093/nar/24.13.2519 Haas, 1995, The GTPase Ypt7p of Saccharomyces cerevisiae is required on both partner vacuoles for the homotypic fusion step in vacuole inheritance, EMBO J., 14, 5258, 10.1002/j.1460-2075.1995.tb00210.x Hama, 2000, Analysis of phosphoinositides in protein trafficking, Methods, 20, 465, 10.1006/meth.2000.0959 Han, 1998, Role of substrates and products of PI-3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav, Science, 279, 558, 10.1126/science.279.5350.558 Horazdovsky, 1994, VPS21 encodes a rab5-like GTP binding protein that is required for the sorting of yeast vacuolar proteins, EMBO J., 13, 1297, 10.1002/j.1460-2075.1994.tb06382.x Huijgbregts, 2000, Lipid metabolism and regulation of membrane trafficking, Traffic, 1, 195, 10.1034/j.1600-0854.2000.010301.x Krugmann, 2002, Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices, Mol. Cell, 9, 95, 10.1016/S1097-2765(02)00434-3 Kucharczyk, 2001, The Ccz1 protein interacts with Ypt7 GTPase during fusion of multiple transport intermediates with the vacuole in S. cerevisiae, J. Cell Sci., 114, 3137, 10.1242/jcs.114.17.3137 Lazar, 1997, Vesicular transport: how many Ypt/Rab-GTPases make a eukaryotic cell?, Trends Biochem. Sci., 22, 468, 10.1016/S0968-0004(97)01150-X Mayer, 2001, What drives membrane fusion in eukaryotes?, Trends Biochem. Sci., 26, 717, 10.1016/S0968-0004(01)01984-3 Mayer, 2000, Phosphatidylinositol-4, 5-bisphosphate regulates two steps of homotypic vacuole fusion, Mol. Biol. Cell, 11, 807, 10.1091/mbc.11.3.807 Müller, 2001, Cdc42p functions at the docking stage of yeast vacuole membrane fusion, EMBO J., 20, 5657, 10.1093/emboj/20.20.5657 Odorizzi, 2000, Phosphoinositide signaling and the regulation of membrane trafficking in yeast, Trends Biochem. Sci., 25, 229, 10.1016/S0968-0004(00)01543-7 Piper, 2001, Late endosomes: sorting and partitioning in multivesicular bodies, Traffic, 2, 612, 10.1034/j.1600-0854.2001.20904.x Price, 2000, The docking stage of yeast vacuole fusion requires the transfer of proteins from a cis-SNARE complex to a Rab/Ypt protein, J. Cell Biol., 148, 1231, 10.1083/jcb.148.6.1231 Reggiori, 2001, Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targeting, EMBO J., 20, 5176, 10.1093/emboj/20.18.5176 Rossman, 2002, A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange, EMBO J., 21, 1315, 10.1093/emboj/21.6.1315 Sachse, 2002, Endosomes: multi-purpose designs for integrating housekeeping and specialized tasks, Histochem. Cell. Biol., 117, 91, 10.1007/s00418-001-0348-0 Sambrook, 1989, vols. 1–3 Sato, 2000, Class C Vps protein complex regulates vacuolar SNARE pairing and is required for vesicle docking/fusion, Mol. Cell, 6, 661, 10.1016/S1097-2765(00)00064-2 Seals, 2000, A Ypt/Rab effector complex containing the Sec1 homolog Vps33p is required for homotypic vacuole fusion, Proc. Natl. Acad. Sci. USA, 97, 9402, 10.1073/pnas.97.17.9402 Soom, 2001, Multiple PIP2 binding sites in Kir2.1 inwardly rectifying potassium channels, FEBS Lett., 490, 49, 10.1016/S0014-5793(01)02136-6 Tall, 1999, The PI-3-phosphate binding protein Vac1p interacts with a Rab GTPase and a Sec1p homologue to facilitate vesicle-mediated vacuolar protein sorting, Mol. Biol. Cell, 10, 1873, 10.1091/mbc.10.6.1873 Thatcher, 1998, Marginal fitness contributions of non-essential genes in yeast, Proc. Natl. Acad. Sci. USA, 95, 253, 10.1073/pnas.95.1.253 Wada, 1990, The SLP1 gene of Saccharomyces cerevisiae is essential for vacuolar morphogenesis and function, Mol. Cell. Biol., 10, 2214 Welch, 2002, P-Rex1, a PtdIns(3,4,5)P3- and Gβγ- regulated guanine-nucleotide exchange factor for Rac, Cell, 108, 809, 10.1016/S0092-8674(02)00663-3 Wera, 2001, Phosphoinositides in yeast: genetically tractable signalling, FEMS Yeast Res., 1406, 1 Wichmann, 1992, Endocytosis in yeast: Evidence for the involvement of a small GTP-binding protein (Ypt7p), Cell, 71, 1131, 10.1016/S0092-8674(05)80062-5 Wickner, 2002, Yeast vacuoles and membrane fusion pathways, EMBO J., 21, 1241, 10.1093/emboj/21.6.1241 Wurmser, 2000, New component of the vacuolar class C-Vps complex couples nucleotide exchange on the Ypt7 GTPase to SNARE-dependent docking and fusion, J. Cell Biol., 151, 551, 10.1083/jcb.151.3.551 Zheng, 1996, Phosphatidylinositol 4,5-bisphosphate provides an alternative to guanine nucleotide exchange factors by stimulating the dissociation of GDP from Cdc42Hs, J. Biol. Chem., 271, 23815, 10.1074/jbc.271.39.23815