A novel embolic middle cerebral artery occlusion model induced by thrombus formed in common carotid artery in rat

Bhatia, 2010, Low rates of acute recanalization with intravenous recombinant tissue plasminogen activator in ischemic stroke: real-world experience and a call for action, Stroke, 41, 2254, 10.1161/STROKEAHA.110.592535 del Zoppo, 1998, PROACT: a phase II randomized trial of recombinant pro-urokinase by direct arterial delivery in acute middle cerebral artery stroke. PROACT investigators. Prolyse in acute cerebral thromboembolism, Stroke, 29, 4, 10.1161/01.STR.29.1.4 Dinapoli, 2006, Selective MCA occlusion: a precise embolic stroke model, J. Neurosci. Methods, 154, 233, 10.1016/j.jneumeth.2005.12.026 Dirnagl, 1989, Continuous measurement of cerebral cortical blood flow by laser-Doppler flowmetry in a rat stroke model, J. Cereb. Blood Flow Metab., 9, 589, 10.1038/jcbfm.1989.84 Hacke, 2008, Thrombolysis with alteplase 3 to 4.5hours after acute ischemic stroke, N. Engl. J. Med., 359, 1317, 10.1056/NEJMoa0804656 Hoda, 2011, Sex-independent neuroprotection with minocycline after experimental thromboembolic stroke, Exp. Trans. Stroke Med., 3, 16, 10.1186/2040-7378-3-16 Lee, 2012, Asiatic acid attenuates infarct volume, mitochondrial dysfunction, and matrix metalloproteinase-9 induction after focal cerebral ischemia, Stroke, 43, 1632, 10.1161/STROKEAHA.111.639427 Li, 2013, Comparative analysis of the neurovascular injury and functional outcomes in experimental stroke models in diabetic Goto-Kakizaki rats, Brain Res., 1541, 106, 10.1016/j.brainres.2013.10.021 Martini, 2007, Hyperglycemia in acute ischemic stroke: a vascular perspective, J. Cereb. Blood Flow Metab.: Off. J. Int. Soc. Cereb. Blood Flow Metab., 27, 435, 10.1038/sj.jcbfm.9600355 Roger, 2012, Heart disease and stroke statistics — 2012 update: a report from the American Heart Association, Circulation, 125, e2, 10.1161/CIR.0b013e31823ac046 Sicard, 2009, Animal models of focal brain ischemia, Exp. Trans. Stroke Med., 1, 7, 10.1186/2040-7378-1-7 van Gorp, 2014, Translation of the rat thoracic contusion model; part 2 — forward versus backward locomotion testing, Spinal Cord, 52, 529, 10.1038/sc.2014.73 Yonemori, 1998, Evaluation of a motor deficit after chronic focal cerebral ischemia in rats, J. Cereb. Blood Flow Metab., 18, 1099, 10.1097/00004647-199810000-00006 Zhang, 1997, A rat model of focal embolic cerebral ischemia, Brain Res., 766, 83, 10.1016/S0006-8993(97)00580-5 Zhu, 2010, Annexin A2 combined with low-dose tPA improves thrombolytic therapy in a rat model of focal embolic stroke, J. Cereb. Blood Flow Metab.: Off. J. Int. Soc. Cereb. Blood Flow Metab., 30, 1137, 10.1038/jcbfm.2009.279