A novel HPLC method for analysis of atosiban and its five related substances in atosiban acetate injection

Buscher, 2001, Effects of oxytocin receptor antagonist atosiban on pregnant myometrium in vitro, Obstet. Gynecol., 98, 117 Thornton, 2003, The drugs we deserve, Bjog Int. J. Obstet. Gynaecol., 110, 969, 10.1111/j.1471-0528.2003.11111.x D’Hondt, 2014, Related impurities in peptide medicines, J. Pharm. Biomed. Anal., 101, 2, 10.1016/j.jpba.2014.06.012 Wellnitz, 1999 Richter, 2005, Tocolysis with atosiban: experience in the management of premature labor before 24 weeks of pregnancy, Arch. Gynecol. Obstet., 272, 26, 10.1007/s00404-004-0652-8 G. Worldwide Atosiban versus Beta-agonists Study, 2001, Effectiveness and safety of the oxytocin antagonist atosiban versus beta-adrenergic agonists in the treatment of preterm labour. The Worldwide Atosiban versus Beta-agonists Study Group, BJOG, 108, 133, 10.1111/j.1471-0528.2001.00043.x Husslein, 2006, Clinical practice evaluation of atosiban in preterm labour management in six European countries, BJOG, 113, 105, 10.1046/j.1471-0528.2003.00041.x-i1 Kashanian, 2005, Atosiban and nifedipin for the treatment of preterm labor, Int. J. Gynaecol. Obstet., 91, 10, 10.1016/j.ijgo.2005.06.005 Rastogi, 2018 Liang, 2009 Burinsky, 1992, Characterization of a synthetic peptide impurity by fast‐atom bombardment–Tandem mass spectrometry and gas chromatography–Mass spectrometry, J. Pharm. Sci., 81, 597, 10.1002/jps.2600810627 Oyler, 1996, Hydrophilic interaction chromatography on amino-silica phases complements reversed-phase high-performance liquid chromatography and capillary electrophoresis for peptide analysis, J. Chromatogr. A, 724, 378, 10.1016/0021-9673(95)00987-6 Kannan, 2010, Quantitative determination of oxytocin receptor antagonist atosiban in rat plasma by liquid chromatography–tandem mass spectrometry, J. Chromatogr. B, 878, 1069, 10.1016/j.jchromb.2010.03.011 Appala Raju, 2014 Hájková, 2003, Simultaneous determination of methylparaben, propylparaben, hydrocortisone acetate and its degradation products in a topical cream by RP-HPLC, J. Pharm. Biomed. Anal., 32, 921, 10.1016/S0731-7085(03)00193-6 Aguilar, 2003 Murphy Goodwin, 1995, The pharmacokinetics of the oxytocin antagonist atosiban in pregnant women with preterm uterine contractions, Am. J. Obstet. Gynecol., 173, 913, 10.1016/0002-9378(95)90365-8