A novel 5-Fluorocuracil multiple-nanoemulsion used for the enhancement of oral bioavailability in the treatment of colorectal cancer

Saudi Journal of Biological Sciences - Tập 29 - Trang 3704-3716 - 2022
Niyaz Ahmad1, Ahmed A. Albassam2, Mohd Faiyaz Khan2, Zabih Ullah3, Taysser Mohammed Buheazah1, Hussain Salman AlHomoud1, Hassan Ali Al-Nasif1
1Department of Pharmaceutics, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia
2Department of Clinical Pharmacy, College of Pharmacy, Prince Sattam bin Abdulaziz University, Alkharj, Saudi Arabia
3Department of Pharmaceutical Sciences, College of Pharmacy and Dentistry, Buraydah Colleges, Alqassim, Saudi Arabia

Tài liệu tham khảo

Ahmad, 2012, Assam Bora rice starch based biocompatible mucoadhesive microsphere for targeted delivery of 5-fluorouracil in colorectal cancer, Mol. Pharm., 9, 2986, 10.1021/mp300289y Ahmad, 2018, Enhancement of oral bioavailability of doxorubicin through surface modified biodegradable polymeric nanoparticles, Chem. Cent. J., 12, 65, 10.1186/s13065-018-0434-1 Ahmad, 2019, Preparation of a novel curcumin nanoemulsion by ultrasonication and its comparative effects in wound healing and the treatment of inflammation, RSC Advances., 9, 20192, 10.1039/C9RA03102B Ahmad, 2020, A comparative ex vivo permeation evaluation of a novel 5-Fluorocuracil nanoemulsion-gel by topically applied in the different excised rat, goat, and cow skin, Saudi J. Biol. Sci., 27, 1024, 10.1016/j.sjbs.2020.02.014 Ahmad, 2017, Enhancement of Quercetin Oral Bioavailability by Self-Nanoemulsifying Drug Delivery System and their Quantification Through Ultra High-Performance Liquid Chromatography and Mass Spectrometry in Cerebral Ischemia, Drug Res (Stuttg)., 67, 564, 10.1055/s-0043-109564 Ahmad, 2018, Ultrasonication techniques used for the preparation of novel Eugenol-Nanoemulsion in the treatment of wounds healings and anti-inflammatory, Journal of Drug Delivery Science and Technology, 46, 461, 10.1016/j.jddst.2018.06.003 Alanazi, 2015, Formulation and evaluation of cholesterol-rich nanoemulsion (LDE) for drug delivery potential of cholesteryl-maleoyl-5-fluorouracil, Pharm. Dev. Technol., 20, 266, 10.3109/10837450.2013.860551 Arias, 2008, Novel strategies to improve the anticancer action of 5-fluorouracil by using drug delivery systems, Molecules., 13, 2340, 10.3390/molecules13102340 Avadi, 2011, Ex vivo evaluation of insulin nanoparticles using chitosan and arabic gum, ISRN Pharm., 2011, 1 Bobin-Dubigeon, 2013, A new, validated wipe-sampling procedure coupled to LC-MS analysis for the simultaneous determination of 5-fluorouracil, doxorubicin and cyclophosphamide in surface contamination, J. Anal. Toxicol., 37, 433, 10.1093/jat/bkt045 Boyle, 2005, Mortality and survival in breast and colorectal cancer, Nat. Clin. Pract. Oncol., 2, 424, 10.1038/ncponc0288 Boyle, 2000, ABC of colorectal cancer: Epidemiology, BMJ., 321, 805, 10.1136/bmj.321.7264.805 Büchel, 2013, LC-MS/MS method for simultaneous analysis of uracil, 5,6-dihydrouracil, 5-fluorouracil and 5-fluoro-5,6-dihydrouracil in human plasma for therapeutic drug monitoring and toxicity prediction in cancer patients, Biomed. Chromatogr., 27, 7, 10.1002/bmc.2741 Buyukozturk, 2010, Impact of emulsion-based drug delivery systems on intestinal permeability and drug release kinetics, J. Control Release., 142, 22, 10.1016/j.jconrel.2009.10.005 Chen, 2010, Determination of eniluracil and 5-fluorouracil in human plasma by LC-MS/MS, Bioanalysis., 2, 2011, 10.4155/bio.10.152 Cosco, 2009, Novel PEG-coated niosomes based on bola-surfactant as drug carriers for 5-fluorouracil, Biomed. Microdevices., 11, 1115, 10.1007/s10544-009-9328-2 Dong, 2013, Improved stability and tumor targeting of 5-fluorouracil by conjugation with hyaluronan, J. Appl. Polym. Sci., 130, 927, 10.1002/app.39247 Ferlay, 2004 Ganti, 2013, Pharmacokinetic application of a bio-analytical LC-MS method developed for 5-fluorouracil and methotrexate in mouse plasma, brain and urine, Biomed Chromatogr., 27, 994, 10.1002/bmc.2893 Garti, 1997, Double emulsions: scope, limitations and new achievements, Colloids Surf A., 123, 233, 10.1016/S0927-7757(96)03809-5 Gelderblom, 2001, Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation, Eur. J. Cancer., 37, 1590, 10.1016/S0959-8049(01)00171-X Gupta, 2005, AOT water-in-oil microemulsions as a penetration enhancer in transdermal drug delivery of 5-fluorouracil, Colloids and Surfaces B: Biointerfaces, 41, 25, 10.1016/j.colsurfb.2004.09.008 Hanson, 2008, Nanoscale double emulsions stabilized by single-component block copolypeptides, Nature., 455, 85, 10.1038/nature07197 Kiss, 2013, Kinetic analysis of the toxicity of pharmaceutical excipients Cremophor EL and RH40 on endothelial and epithelial cells, J. Pharm. Sci., 102, 1173, 10.1002/jps.23458 Li, 2008, Pharmacokinetic characteristics and anticancer effects of 5-fluorouracil loaded nanoparticles, BMC Cancer., 8, 103, 10.1186/1471-2407-8-103 Licea-Perez, 2009, Development of a sensitive and selective LC-MS/MS method for the determination of alpha-fluoro-beta-alanine, 5-fluorouracil and capecitabine in human plasma, J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 877, 1040, 10.1016/j.jchromb.2009.02.025 Lin, 2012, 5-Fluorouracil encapsulated HA/PLGA composite microspheres for cancer therapy, J. Mater. Sci. Mater. Med., 23, 2453, 10.1007/s10856-012-4723-2 Liu, 2010, Determination of tegafur, 5-fluorouracil, gimeracil and oxonic acid in human plasma using liquid chromatography-tandem mass spectrometry, J. Pharm. Biomed. Anal., 52, 550, 10.1016/j.jpba.2010.01.026 Longley, 2003, Reviews and comments from the nature publishing group, Nat. Rev. Cancer, 3, 330, 10.1038/nrc1074 Loscertales, 2002, Micro/nano encapsulation via electrifies coaxial liquid jets, Science., 295, 1695, 10.1126/science.1067595 Lu, 2012, Absorption, disposition and pharmacokinetics of nanoemulsions, Curr Drug Metab., 13, 396, 10.2174/138920012800166544 Pangeni, 2016, Multiple nanoemulsion system for an oral combinational delivery of oxaliplatin and 5-fluorouracil: preparation and in vivo evaluation, Int. J. Nanomedicine., 11, 6379, 10.2147/IJN.S121114 Parkin, 2005, Global cancer statistics, 2002, CA Cancer J. Clin., 55, 74, 10.3322/canjclin.55.2.74 Peer, 2012, Development and utilization of a combined LC-UV and LC-MS/MS method for the simultaneous analysis of tegafur and 5-fluorouracil in human plasma to support a phase I clinical study of oral UFT®/leucovorin. J, Chromatogr. B Analyt. Technol. Biomed. Life Sci., 898, 32, 10.1016/j.jchromb.2012.04.010 Presant, 2002, Does leucovorin alter the intratumoral pharmacokinetics of 5-fluorouracil? A Southwest oncology group study, Invest. New Drugs., 20, 369, 10.1023/A:1020651311866 Remaud, 2005, Sensitive MS/MS-liquid chromatography assay for simultaneous determination of tegafur, 5-fluorouracil and 5-fluorodihydrouracil in plasma, J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 824, 153, 10.1016/j.jchromb.2005.07.023 Ruan, 2006, Prediction of human absorption of natural compounds by the non-everted rat intestinal sac model, Eur. J. Med. Chem., 41, 605, 10.1016/j.ejmech.2006.01.013 Schmidts, 2011, Protective effect of drug delivery systems against the enzymatic degradation of dermally applied DNAzyme, Int. J. Pharm., 410, 75, 10.1016/j.ijpharm.2011.03.023 Schmidts, 2012, Development of drug delivery systems for the dermal application of therapeutic DNAzymes, Int. J. Pharm., 431, 61, 10.1016/j.ijpharm.2012.04.034 Schwarz, 2012, Optimisation of multiple W/O/W nanoemulsions for dermal delivery of aciclovir, Int. J. Pharm., 435, 69, 10.1016/j.ijpharm.2011.11.038 Shah, 2011, Polysaccharides: a targeting strategy for colonic drug delivery, Expert Opin. Drug Deliv., 8, 779, 10.1517/17425247.2011.574121 Shakeel, 2014, Double w/o/w nanoemulsion of 5-fluorouracil for self-nanoemulsifying drug delivery system, J. Mol. Liq., 200, 183, 10.1016/j.molliq.2014.10.013 Shakeel, 2013, Ultra fine super selfnanoemulsifying drug delivery system (SNEDDS) enhanced solubility and dissolution of indomethacin, J. Mol. Liq., 180, 89, 10.1016/j.molliq.2013.01.008 Shanmugam, 2011, Solid selfnanoemulsifying drug delivery system (S-SNEDDS) containing phosphatidycholine for enhanced bioavailability of highly lipophilic bioactive carotenoid lutein, Eur. J. Pharm. Biopharm., 79, 250, 10.1016/j.ejpb.2011.04.012 Shishu, 2012, Development and evaluation of novel microemulsion based oral formulations of 5-fluorouracil using non-everted rat intestine sac model, Drug Dev. Ind. Pharm., 38, 294, 10.3109/03639045.2011.602407 Sigward, 2013, Formulation and cytotoxicity evaluation of new self-emulsifying multiple W/O/W nanoemulsions, Int. J. Nanomedicine., 8, 611 Thomas, 2011, Development of a liposomal nanoparticle formulation of 5-fluorouracil for parenteral administration: formulation design, pharmacokinetics and efficacy, J. Control Release., 150, 212, 10.1016/j.jconrel.2010.11.018 Thomas, 2012, In vitro and in vivo performance of novel super saturated self-nanoemulsifying drug delivery systems (super-SNEDDS), J. Control. Release., 160, 25, 10.1016/j.jconrel.2012.02.027 Udata, 2003, Enhanced transport of a novel anti-HIV agent – cosalane and its congeners across human intestinal epithelial (Caco-2) cell monolayers, Int. J. Pharm., 250, 157, 10.1016/S0378-5173(02)00523-9 US FDA. Guidance for Industry Bioanalytical Method Validation; 2001. Available from:http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/UCM070107.pdf. [Last accessed on 2018 May 24]. Vainchtein, 2010, A new, validated HPLC-MS/MS method for the simultaneous determination of the anti-cancer agent capecitabine and its metabolites: 5'-deoxy-5-fluorocytidine, 5'-deoxy-5-fluorouridine, 5-fluorouracil and 5-fluorodihydrouracil, in human plasma, Biomed. Chromatogr., 24, 374 World Cancer Research Fund and American Institute for Cancer Research. Food, Nutrition, Physical Activity, and the Prevention of Cancer: A Global Perspective. Washington, DC: American Institute for Cancer Research; 2007. World Health Organization. Cancer Incidence in Five Continents. Lyon: The World Health Organization and The International Agency for Research on Cancer; 2002. Yanyu, 2012, The influence of the structure and the composition of water/AOT-Tween 85/IPM microemulsion system on transdermal delivery of 5-fluorouracil, Drug Dev. Ind. Pharm., 38, 1521, 10.3109/03639045.2012.654795 Yassin, 2010, Optimization of 5-flurouracil solid-lipid nanoparticles: a preliminary study to treat colon cancer, Int. J. Med. Sci., 7, 398, 10.7150/ijms.7.398 Youssof, 2019, Bacterial Ghosts Carrying 5-Fluorouracil: A Novel Biological Carrier for Targeting Colorectal Cancer, AAPS PharmSciTech., 20, 20, 10.1208/s12249-018-1249-z Zhang, 2012, In vitro study of ethosome penetration in human skin and hypertrophic scar tissue, Nanomedicine., 8, 1026, 10.1016/j.nano.2011.10.006 Zhao, 2011, Water-in-oil-in-water double nanoemulsion induced by CO2, Phys Chem Chem Phys., 13, 684, 10.1039/C0CP00869A