Phương trình dự đoán mới để đánh giá tỷ lệ mỡ cơ thể của phụ nữ và nguy cơ bệnh tim mạch liên quan đến béo phì

Journal of Endocrinological Investigation - Tập 37 - Trang 511-524 - 2014
A. De Lorenzo1,2, A. Nardi3, L. Iacopino1, E. Domino1, G. Murdolo4, C. Gavrila1, D. Minella1, G. Scapagnini5, L. Di Renzo1
1Division of Clinical Nutrition and Nutrigenomic, Department of Biomedicine and Prevention, University of Tor Vergata, Rome, Italy
2I.N.Di.M, National Institute for Mediterranean Diet and Nutrigenomic, Reggio Calabria, Italy
3Department of Mathematics, University of Rome Tor Vergata, Rome, Italy
4Department of Internal Medicine, Assisi Hospital, Assisi (Perugia), Italy
5University of Molise, Campobasso, Italy

Tóm tắt

Béo phì là một vấn đề sức khỏe cộng đồng toàn cầu do sự liên quan của nó với các bệnh tim mạch và giảm tuổi thọ. Phân loại béo phì phổ biến nhất được thể hiện dưới dạng Chỉ số Khối cơ thể (BMI); tuy nhiên, công thức này là một phương pháp đo lường mỡ không chính xác vì bỏ qua nhiều yếu tố quan trọng khác liên quan. Chỉ số Mỡ cơ thể (BAI) được đề xuất gần đây như một phương pháp gián tiếp để đánh giá tỷ lệ phần trăm mỡ cơ thể (PBF). PBF là một thước đo trực tiếp về tỷ lệ mỡ cơ thể của một người và là một dấu hiệu dự đoán tốt hơn về các bệnh liên quan đến béo phì so với BMI và BAI. Vì béo phì và các bệnh liên quan được coi là dịch bệnh, các công thức chính xác mới cho các nghiên cứu dịch tễ học đang thu hút sự quan tâm của cộng đồng khoa học. Bởi vì việc đo lường trực tiếp thành phần cơ thể có thể khá đắt đỏ, mục tiêu của công trình này là phân tích sự phân bố của PBF bằng phương pháp hấp thụ tia X đôi và tạo ra một phương trình dự đoán mới chỉ sử dụng các phép đo nhân trắc học có thể hữu ích cho các bác sĩ lâm sàng trong việc dễ dàng đánh giá mỡ cơ thể của bệnh nhân nữ. Một mẫu gồm 1.031 phụ nữ Ý da trắng đã được tuyển chọn, và BMI, BAI cùng PBF đã được đánh giá. Nhằm phát triển một mô hình dự đoán PBF, một mô hình hồi quy đa biến đã được khớp với dữ liệu quan sát. Định nghĩa về PBF được công nhận toàn cầu theo giới tính và tuổi tác có thể có những tác động đến sức khỏe cộng đồng. Trong nghiên cứu này, chúng tôi đã phát triển một phương trình PBF dự đoán mới mà không cần đến các dụng cụ y tế hoặc kỹ thuật đo lường chuyên nghiệp và có thể được áp dụng dễ dàng cho phụ nữ Ý.

Từ khóa

#béo phì; tỷ lệ mỡ cơ thể; bệnh tim mạch; sức khỏe cộng đồng; phương trình dự đoán; nhân trắc học

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