A new form of Filgrastim with sustained duration in vivo and enhanced ability to mobilize PBPC in both mice and humans
Tóm tắt
Từ khóa
Tài liệu tham khảo
Welte K, Gabrilove J, Bronchud MH, Platzer E, Morstyn G (1996) Filgrastim (r-metHuG-CSF): the first 10 years. Blood 88:1907
Bronchud, 1987, Phase I/II study of recombinant human granulocyte colony-stimulating factor in patients receiving intensive chemotherapy for small cell lung cancer, Br J Cancer, 56, 809, 10.1038/bjc.1987.295
Ulich, 1988, Kinetics and mechanisms of recombinant human granulocyte-colony stimulating factor-induced neutrophilia, Am J Pathol, 133, 630
Tanaka, 1991, Pharmacokinetics of recombinant human granulocyte colony-stimulating factor in the rat. Single and multiple dosing studies, Drug Metab Dispos, 19, 200
Roskos, 1998, Pharmacology of filgrastim (r-metHuG-CSF), 51
Tanaka, 1991, Pharmacokinetics of recombinant human granulocyte colony-stimulating factor conjugated to poly(ethylene glycol) in rats, Cancer Res, 51, 3710
Delgado C, Francis GE, Fisher D (1992) The uses and properties of PEG-linked proteins.
(1998) In: G Morstyn, TM Dexter, MA Foote (eds) Filgrastim in clinical practice, 2nd edition. New York: Marcel Dekker.
Molineux, 1990, A comparison of hematopoiesis in normal and splenectomized mice treated with granulocyte colony-stimulating factor, Blood, 75, 563, 10.1182/blood.V75.3.563.563
Welte, 1988, Recombinant human granulocyte-colony stimulating factor, Behring Inst Mitt, 83, 102
Molineux, 1995, Continuous subcutaneous infusion of hematopoietic growth factors in mice, Exper Hematol, 23, 880
Schwab, 1998, A phase I study of sustained-duration filgrastim in normal volunteers, Exper Hematol, 26, 709
Roskos, 1999, A cytokinetic model describes the granulopoietic effects of r-metHuG-CSF-SD/01 (SD/01) and the homeostatic regulation of SD/01 clearance in normal volunteers, Clin Pharmacol Ther, 65, 196, 10.1016/S0009-9236(99)80315-4
Cheung, 1998, Modelling of r-metHuG-CSF-SD/01 (SD/01) mediated granulopoiesis in normal animals with mathematical extrapolation to neutropenic settings, Blood, 92, 379A
Roskos, 1998, Cytokinetic model of rmethHuG-CSF-SD/01 (SD/01) mediated granulopoiesis and the and the “self-regulation” of SD/01 elimination in non-small cell lung cancer (NSCLC), Blood, 92, 507A
Mast, 1990, Evaluation of the rapid plasma elimination of recombinant alpha1-proteinase, J Lab Clin Med, 116, 58
Tanaka, 1990, Influence of renal and hepatic failure on the pharmacokinetics of recombinant human granulocyte colony-stimulating factor (KRN8601) in the rat, Cancer Res, 50, 6615
Molineux, 1996, Megakaryocyte growth and development factor accelerates platelet recovery in peripheral blood progenitor cell transplant recipients, Blood, 88, 366, 10.1182/blood.V88.1.366.366
Molineux, 1997, An analysis of the effects of combined treatment with rmGM-CSF and PEG-rHuMGDF in murine bone marrow transplant recipients, Stem Cells, 15, 43, 10.1002/stem.150043
de Haan, 1994, Mutual inhibition of murine erythropoiesis and granulopoiesis during combined erythropoietin, granulocyte colony-stimulating factor, and stem cell factor administration, Blood, 84, 4157, 10.1182/blood.V84.12.4157.bloodjournal84124157
Molineux, 1997, An analysis of the effects of combined treatment with rmGM-CSF and PEG-rHuMGDF in murine bone marrow transplant recipients, Stem Cells, 15, 1, 10.1002/stem.150043
Molineux, 1990, Transplantation potential of peripheral blood stem cells induced by granulocyte colony-stimulating factor, Blood, 76, 2153, 10.1182/blood.V76.10.2153.2153
Lane, 1999, Mobilization of blood-derived stem and progenitor cells in normal subjects by granulocyte-macrophage- and granulocyte-colony-stimulating factors, Transplantation, 39, 39
Baumann, 1996, Mobilisation kinetics of primitive haemopoietic cells following G-CSF with or without chemotherapy for advanced breast cancer, Ann Oncol, 7, 1051, 10.1093/oxfordjournals.annonc.a010498
Lord, 1994, Haemopoietic progenitor and myeloid cell kinetics in humans treated with interleukin-3 and granulocyte/macrophage colony-stimulating factor in combination, Int J Cancer, 59, 483, 10.1002/ijc.2910590409
Lord, 1991, Myeloid cell kinetics in mice treated with recombinant interleukin-3,granulocyte colony-stimulating factor (CSF), or granulocyte-macrophage CSF in vivo, Blood, 77, 2154, 10.1182/blood.V77.10.2154.2154
Capdeville, 1997, A single injection of RO 25-8315, a long-acting pegylated G-CSF mutein, is safe and effective in mobilizing peripheral blood progenitor cells (PBPC) in healthy volunteers. A clinical pharmacology phase I study, Bone Marrow Transplant, 19, S12
Xu, 1997, Safety/tolerability and pharmacokinetics/pharmacodynamics (PK/PD) following administration of ascending subcutaneous doses of a long-acting (5-7 days), chemically modified G-CSF mutein (Ro 25-8315) to healthy subjects, Proc ASCO, 16, 87a
Farese, 1998, A single administration of r-metHuG-CSF-SD/01 (SD/01) significantly improves neutrophil recovery following autologous bone marrow transplantation, Blood, 92, 112A