A new definition for metabolic dysfunction-associated fatty liver disease: An international expert consensus statement

Journal of Hepatology - Tập 73 Số 1 - Trang 202-209 - 2020
Mohammed Eslam1, Philip N. Newsome2,3,4, Shiv Kumar Sarin5, Quentin M. Anstee6,7, Giovanni Targher8, Manuel Romero‐Gómez9, Shira Zelber‐Sagi10,11, Grace Lai‐Hung Wong12, Jean‐François Dufour13,14, Jörn M. Schattenberg15, Takumi Kawaguchi16, Marco Arrese17, Luca Valenti18, Gamal Shiha19, Claudio Tiribelli20, Hannele Yki‐Järvinen21, Jian-Gao Fan22, Henning Grønbæk23, Yusuf Yılmaz24,25, Helena Cortez‐Pinto26, Cláudia P. Oliveira27, Pierre Bédossa28, Leon A. Adams29, Ming‐Hua Zheng30,31, Yasser Fouad32, Wah‐Kheong Chan33, Nahúm Méndez‐Sánchez34, Sang Hoon Ahn35, Laurent Castéra36, Elisabetta Bugianesi37, Vlad Ratziu38, Jacob George1
1Storr Liver Centre, Westmead Institute for Medical Research, Westmead Hospital and University of Sydney, NSW, Australia
2Centre for Liver and Gastrointestinal Research, Institute of Immunology and Immunotherapy, University of Birmingham, UK
3Liver Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
4National Institute for Health Research Biomedical Research Centre at University Hospitals Birmingham NHS Foundation Trust and the University of Birmingham, UK
5Department of Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India
6Newcastle NIHR Biomedical Research Centre, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom
7Translational & Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom
8Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy
9UCM Digestive Diseases, Virgen del Rocio University Hospital, Instituto de Biomedicina de Sevilla, CIBEREHD, University of Seville, Sevilla, Spain
10Department of Gastroenterology, Tel Aviv Medical Center, Tel Aviv, Israel
11School of Public Health, University of Haifa, Haifa, Israel
12Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong
13Department of Biomedical Research, University of Bern, Switzerland
14University Clinic for Visceral Surgery and Medicine, Inselspital, University of Bern. Switzerland
15Department of Medicine, University Medical Centre, Johannes Gutenberg University Mainz, Germany
16Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan
17Departamento de Gastroenterología, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile and Centro de Envejecimiento y Regeneracion (CARE), Departamento de Biologia Celular y Molecular, Facultad de Ciencias Biologicas Pontificia Universidad Catolica de Chile, Santiago, Chile
18Department of Pathophysiology and Transplantation, Università degli Studi di Milano, and Translational Medicine, Department of Transfusion Medicine and Hematology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy
19Hepatology and Gastroenterology Unit, Internal Medicine Department, Faculty of Medicine, Mansoura University, Egypt
20Liver Center, Italian Liver Foundation, Trieste, Italy
21Department of Medicine, University of Helsinki and Helsinki University Hospital, and Minerva Foundation Institute for Medical Research, Helsinki, Finland
22Center for Fatty Liver, Department of Gastroenterology, Xin Hua Hospital Affiliated To Shanghai Jiao Tong University School of Medicine, Shanghai Key Lab of Pediatric Gastroenterology and Nutrition, Shanghai, China
23Department of Hepatology & Gastroenterology, Aarhus University Hospital, Aarhus, Denmark
24Department of Gastroenterology, School of Medicine, Marmara University, Istanbul, Turkey
25Institute of Gastroenterology, Marmara University, Istanbul, Turkey
26Clínica Universitária de Gastrenterologia, Laboratório de Nutrição, Faculdade de Medicina, Universidade de Lisboa, Portugal
27Department of Gastroenterology, University of Sao Paulo School of Medicine, Sao Paulo, Brazil
28Department of Pathology, Physiology and Imaging, Beaujon Hospital Paris Diderot University, Paris, France
29Medical School, Sir Charles Gairdner Hospital Unit, University of Western Australia, Nedlands, WA, Australia
30Institute of Hepatology, Wenzhou Medical University, Wenzhou, China
31NAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
32Department of Gastroenterology, Hepatology and Endemic Medicine, Faculty of Medicine, Minia University Hospitals, Minya, Egypt
33Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
34Liver Research Unit, Medica Sur Clinic & Foundation and Faculty of Medicine. National Autonomous University of Mexico, Mexico City, Mexico
35Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea
36Université Paris VII, Inserm Umr 1149, Centre de Recherche Sur L'inflammation, Paris, France
37Division of Gastroenterology and Hepatology, Department of Medical Sciences, University of Turin, Turin, Italy
38Sorbonne Université, Assistance Publique-Hôpitaux de Paris, Hôpital Pitié Salpêtrière-, Institute of Cardiometabolism and Nutrition (ICAN), Paris, France

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