A multilateral study of the pathogenesis of organ-specific autoimmune diseases

Nikolov, 2009, Pathogenesis of Sjögren's syndrome, Curr Opin Rheumatol, 21, 465, 10.1097/BOR.0b013e32832eba21 Fox, 1994, Sjögren's syndrome. Proposed criteria for classification, Arthritis Rheum, 37, 869 Carlsöö, 1979, The autoimmune submandibular sialoadenitis of the NZB/NZW hybrid mice. A light and electron microscopical investigation, Arch Otorhinolaryngol, 225, 57, 10.1007/BF00455876 Talal, 1983, Interleukins in experimental autoimmune disease, Adv Exp Med Biol, 166, 105, 10.1007/978-1-4757-1410-4_11 Wicker, 1992, Autoimmune syndromes in major histocompatibility complex (MHC) congenic strains of nonobese diabetic (NOD) mice. The NOD MHC is dominant for insulitis and cyclophosphamide-induced diabetes, J Exp Med, 176, 67, 10.1084/jem.176.1.67 Tsubata, 1996, Autoimmune disease of exocrine organs in immunodeficient alymphoplasia mice: a spontaneous model for Sjögren's syndrome, Eur J Immunol, 26, 2742, 10.1002/eji.1830261129 Takahashi, 1998, Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state, Int Immunol, 10, 1969, 10.1093/intimm/10.12.1969 Haneji, 1994, A new animal model for primary Sjögren's syndrome in NFS/sld mutant mice, J Immunol, 153, 2769, 10.4049/jimmunol.153.6.2769 Haneji, 1997, Identification of alpha-fodrin as a candidate autoantigen in primary Sjögren's syndrome, Science, 276, 604, 10.1126/science.276.5312.604 Ishimaru, 2001, Possible role of organ-specific autoantigen for Fas ligand-mediated activation-induced cell death in murine Sjögren's syndrome, J Immunol, 167, 6031, 10.4049/jimmunol.167.10.6031 McCartney-Francis, 1996, Autoimmune Sjögren's-like lesions in salivary glands of TGF-beta1-deficient mice are inhibited by adhesion-blocking peptides, J Immunol, 157, 1306, 10.4049/jimmunol.157.3.1306 Saito, 1999, Fas ligand-mediated exocrinopathy resembling Sjögren's syndrome in mice transgenic for IL-10, J Immunol, 162, 2488, 10.4049/jimmunol.162.5.2488 Shen, 2006, Development of autoimmunity in IL-14alpha-transgenic mice, J Immunol, 177, 5676, 10.4049/jimmunol.177.8.5676 Anderson, 2002, Projection of an immunological self shadow within the thymus by the aire protein, Science, 298, 1395, 10.1126/science.1075958 Kurobe, 2006, CCR7-dependent cortex-to-medulla migration of positively selected thymocytes is essential for establishing central tolerance, Immunity, 24, 165, 10.1016/j.immuni.2005.12.011 Ishimaru, 2008, Expression of the retinoblastoma protein RbAp48 in exocrine glands leads to Sjögren's syndrome-like autoimmune exocrinopathy, J Exp Med, 205, 2915, 10.1084/jem.20080174 Suri-Payer, 2001, The 3-day thymectomy model for induction of multiple organ-specific autoimmune diseases, Curr Protoc Immunol, 15, 15 Kojima, 1976, Spontaneous development of autoimmune thyroiditis in neonatally thymectomized mice, Lab Invest, 34, 550 Teague, 1970, Autoimmune phenomena and renal disease in mice: role of thymectomy, aging, and involution of immunologic capacity, Lab Invest, 22, 121 Tung, 1987, Murine autoimmune oophoritis, epididymoorchitis, and gastritis induced by day 3 thymectomy, Am J Pathol, 126, 303 Sohn, 2007, Apoptosis during negative selection of autoreactive thymocytes, Curr Opin Immunol, 19, 10.1016/j.coi.2007.06.001 Anderson, 2011, Aire and T cell development, Curr Opin Immunol, 23, 198, 10.1016/j.coi.2010.11.007 Taniguchi, 2010, The role of Aire in clonal selection, Immunol Cell Biol, 89, 40, 10.1038/icb.2010.132 Peterson, 2005, Autoimmune polyendocrinopathy syndrome type 1 (APS1) and AIRE gene: new views on molecular basis of autoimmunity, J Autoimmun, 25, 49, 10.1016/j.jaut.2005.09.022 Schecter, 2006, Dioxins: an overview, Environ Res, 101, 419, 10.1016/j.envres.2005.12.003 Kerkvliet, 2001, Recent advances in understanding the mechanisms of TCDD immunotoxicity, Int Immunopharmacol, 2, 277, 10.1016/S1567-5769(01)00179-5 Ishimaru, 2009, Neonatal exposure to low-dose 2,3,7,8-tetrachlorodibenzo-p-dioxin causes autoimmunity due to the disruption of T cell tolerance, J Immunol, 182, 6576, 10.4049/jimmunol.0802289 Sakaguchi, 2005, Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self, Nat Immunol, 6, 345, 10.1038/ni1178 Hori, 2003, Control of regulatory T cell development by the transcription factor Foxp3, Science, 299, 1057, 10.1126/science.1079490 Schneider, 2007, CCR7 is required for the in vivo function of CD4+ CD25+ regulatory T cells, J Exp Med, 204, 735, 10.1084/jem.20061405 Ishimaru, 2010, In situ patrolling of regulatory T cells is essential for protecting autoimmune exocrinopathy, PLoS One, 5, 10.1371/journal.pone.0008588 Ishimaru, 2012, CCR7 with S1P1 signaling through AP-1 for migration of Foxp3+ regulatory T-cells controls autoimmune exocrinopathy, Am J Pathol, 180, 199, 10.1016/j.ajpath.2011.09.027 Whitacre, 2001, Sex differences in autoimmune disease, Nat Immunol, 2, 777, 10.1038/ni0901-777 Stassi, 2002, Autoimmune thyroid disease: new models of cell death in autoimmunity, Nat Rev Immunol, 2, 195, 10.1038/nri750 Ishimaru, 1999, Estrogen deficiency accelerates autoimmune exocrinopathy in murine Sjögren's syndrome through Fas-mediated apoptosis, Am J Pathol, 155, 173, 10.1016/S0002-9440(10)65111-5 Ishimaru, 2006, Novel role for RbAp48 in tissue-specific, estrogen deficiency-dependent apoptosis in the exocrine glands, Mol Cell Biol, 26, 2924, 10.1128/MCB.26.8.2924-2935.2006