A modular simulation package for fed-batch fermentation: penicillin production

Atkinson, 1991

Bailey, 1986

Bajpai, 1980, A mechanistic model for penicillin production, Journal of Chemical Technology and Biotechnology, 30, 330, 10.1002/jctb.503300140

Bajpai, 1981, Evaluation of feeding strategies in carbon-regulated secondary metabolite production through mathematical modelling, Biotechnology and Bioengineering, 23, 717, 10.1002/bit.260230406

Birol, 2002, A morphologically structured model for penicillin production, Biotechnology and Bioengineering, 77, 538, 10.1002/bit.10115

Cinar, A., & Undey, C. (1999). Statistical process and controller performance monitoring. Proceedings of the American Control Conference (pp. 2625–2639). vol. 4. San Diego, CA.

Constantinides, A., Spencer, J., & Gaden, E. J. (1970). Optimization of batch fermentation processes. I. Development of mathematical models for batch penicillin fermentations. Biotechnology and Bioengineering, 12, 803.

Downs, 1993, A plant-wide industrial control problem, Computers and Chemical Engineering, 13, 21

Heijnen, 1979, Application of balancing methods in modeling the penicillin fermentation, Biotechnology and Bioengineering, 21, 2175, 10.1002/bit.260211204

Kourti, 1996, Multivariate SPC methods for process and product monitoring, Journal of Quality Technology, 28, 409, 10.1080/00224065.1996.11979699

Marlin, 1995

Menezes, 1994, Mathematical modelling of industrial pilot-plant penicillin-G fed-batch fermentastions, Journal of Chemical Technology and Biotechnology, 61, 123, 10.1002/jctb.280610207

Metz, 1981, Method for quantitative representation of the morphology of molds, Biotechnology and Bioengineering, 23, 149, 10.1002/bit.260230110

Miller, 1998, Contribution plots: the missing link in multivariate quality control, International Journal of Applied Mathametics and Computer Science, 8, 775

Montague, 1986, Growth monitoring and control through computer-aided on-line mass balancing in fed-batch penicillin fermentation, Canadian Journal of Chemical Engineering, 64, 567, 10.1002/cjce.5450640407

Mou, 1983, Modeling and adaptive control of fed-batch penicillin production, Biotechnology and Bioengineering, 25, 225, 10.1002/bit.260250118

Nestaas, 1983, Computer control of the penicillin fermentation using the filtration probe in conjunction with a structured process model, Biotechnology and Bioengineering, 25, 781, 10.1002/bit.260250314

Nielsen, 1997

Nielsen, 1994

Nomikos, 1994, Monitoring batch processes using multiway principal component analysis, American Institute of Chemical Engineers Journal, 40, 1361, 10.1002/aic.690400809

Pirt, 1967, Effect of growth rate on the synthesis of penicillin by Penicillium chrysogenum in batch and chemostat cultures, Applied Microbiology, 15, 1284, 10.1128/AEM.15.6.1284-1290.1967

Shuler, 2002

Undey, C., Tatara, E., Williams, B., Birol, G., & Cinar, A. (2000). A hybrid supervisory knowledge-based system for monitoring penicillin fermentation. Proceedings of American Control Conference (pp. 3944–3948). vol. 6. Chicago, IL.

Wold, 1987, Multi-way principal component and PLS analysis, Journal of Chemometrics, 1, 41, 10.1002/cem.1180010107