A metastatic gastric tumor originating from a pleomorphic rhabdomyosarcoma of the extremity: a case report and literature review
Tóm tắt
Pleomorphic rhabdomyosarcoma is a rare and aggressive variant of rhabdomyosarcoma that usually occurs only in adults aged 45 years or older. Gastric metastasis from a soft-tissue sarcoma of the extremity is likewise very rare, with only a few previously reported cases. Here, we describe the case of a 52-year-old man with gastric metastasis who underwent en bloc excision of the primary tumor and distal gastrectomy but died 6 months after surgery due to lung metastases. This is, to our knowledge, the first reported case of gastric metastasis from pleomorphic rhabdomyosarcoma of the extremity. In cases such as these, patients may have widespread disease, and thus, surgery may only have a limited role in its management.
Tài liệu tham khảo
Enzinger F, Weiss S. (2007) Soft tissue tumors, 5th edn. Mosby, St. Louis
Esnaola NF, Rubin BP, Baldini EH et al (2001) Response to chemotherapy and predictors of survival in adult rhabdomyosarcoma. Ann Surg 234:215–223
Ferrari A, Dileo P, Casanova M et al (2003) Rhabdomyosarcoma in adults. A retrospective analysis of 171 patients treated at a single institution. Cancer 98:571–580
Little DJ, Ballo MT, Zagars GK et al (2002) Adult rhabdomyosarcoma: outcome following multimodality treatment. Cancer 95:377–388
Adams HW, Adkins JR, Rehak EM (1983) Malignant fibrous histiocytoma presenting as a bleeding gastric ulcer. Am J Gastroenterol 78:212–213
Obata S, Mizutani J, Miura K et al (1993) Gastrointestinal metastases of an angiosarcoma. Endoscopy 25:438
Atalay C, Irkkan C, Pak I et al (2003) Gastroduodenal metastases in a clear cell sarcoma patient. J Exp Clin Cancer Res 22:147–150
Anjiki H, Yamamoto T, Ishii T et al (2004) Synovial sarcoma metastatic to stomach and duodenum. Gastrointest Endosc 59:75
Nakajima Y, Kakizaki S, Kanda D et al (2005) Pancreatic and gastric metastases of leiomyosarcoma arising in the left leg. Int J Clin Oncol 10:342–347
Akatsu Y, Saikawa Y, Kubota T et al (2006) Metastatic gastric cancer from malignant fibrous histiocytoma: report of a case. Surg Today 36:385–389
Hashimoto D, Watanabe M, Hayashi N et al (2009) Gastric metastasis of malignant fibrous histiocytoma diagnosed preoperatively by endoscopic ultrasound-guided fine-needle aspiration biopsy: report of a case. Surg Today 39:1073–1075
Lee GW, Kim TH, Min HJ et al (2010) Unusual gastrointestinal metastases from an alveolar soft part sarcoma. Dig Endosc 22:137–139
Contreras Ibanez JA, Navas Garcia N, Diaz Gomez L (2011) Mestastatic gastric cancer from malignant fibrous histiocytoma. Rev Esp Enferm Dig 103:44–46
Stinchcombe TE, Socinski MA, Gangarosa LM et al (2006) Lung cancer presenting with a solitary colon metastasis detected on positron emission tomography scan. J Clin Oncol 24:4939–4940
Crist W, Gehan EA, Ragab AH et al (1995) The Third Intergroup Rhabdomyosarcoma Study. J Clin Oncol 13:610–630
Crist WM, Anderson JR, Meza JL et al (2001) Intergroup rhabdomyosarcoma study-IV: results for patients with nonmetastatic disease. J Clin Oncol 19:3091–3102
Maurer HM, Beltangady M, Gehan EA et al (1988) The Intergroup Rhabdomyosarcoma Study-I. A final report. Cancer 61:209–220
Maurer HM, Gehan EA, Beltangady M et al (1993) The Intergroup Rhabdomyosarcoma Study-II. Cancer 71:1904–1922
Hollowood K, Fletcher CD (1994) Rhabdomyosarcoma in adults. Semin Diagn Pathol 11:47–57