A mechanism of inhibition of short-wavelength ultraviolet light-induced deamination of pyrimidine bases by ascorbic acid

Mutation Research Letters - Tập 302 - Trang 183-190 - 1993
John C. Deutsch1, J.Fred Kolhouse2
1Divisions of Gastroenterology, Department of Medicine, The Veterans Affairs Hospital, and the University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA
2Divisions of Hematology, Department of Medicine, The Veterans Affairs Hospital, and the University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA

Tài liệu tham khảo

Brash, 1987, Photoproduct frequency is not the major determination of UV base substitution hot spots or cold spots in human cells, 84, 3782 Cerutti, 1985, Prooxidant states and tumor promotion, Science, 227, 375, 10.1126/science.2981433 Doniger, 1981, Ultraviolet light action spectra for neoblastic transformation and lethality of Syrian hamster embryo cells correlate with spectrum for pyrimidine dimer formation in cellular DNA, 78, 2378 Duker, 1984, Perturbations of enzymatic uracil excision due to guanine modifications in DNA, Cancer Res., 44, 602 Duncan, 1980, Mutagenic deamination of cytosine residues in DNA, Nature (London), 287, 560, 10.1038/287560a0 Ehrlich, 1986, DNA cytosine methylation and heat-induced deamination, Biosci. Rep., 6, 387, 10.1007/BF01116426 Frei, 1988, Antioxidant defenses and lipid peroxidation in human blood plasma, 85, 9748 Frei, 1988, Ascorbate is an outstanding antioxidant in human blood plasma, 85, 9748 Freudenheim, 1990, A case-control study of diet and rectal cancer in western New York, Am. J. Epidemiol., 131, 612, 10.1093/oxfordjournals.aje.a115545 Fry, 1989, Ultraviolet Radiation-Induced Skin Center, 321 Hayakawa, 1978, Repair of deaminated cytosine residues of DNA: biological significance of the absence of uracil from DNA, Biochem. Biophys. Res. Commun., 83, 1312, 10.1016/0006-291X(78)91364-5 Imlay, 1988, DNA damage and oxygen radical toxicity, Science, 240, 1302, 10.1126/science.3287616 Jaffe, 1984, Vitamin C, 199 Lindahl, 1974, Heat-induced deamination of cytosine residues in deoxyribonucleic acid, Biochemistry, 13, 3405, 10.1021/bi00713a035 Lo, 1973, Inhibition of carcinogen formation in skin irradiated with ultraviolet light, Nature (London), 246, 489, 10.1038/246489a0 Olsen, 1989, Molecular cloning of human uracil-DNA glycosylase, a highly conserved DNA repair enzyme, EMBO J., 8, 3121, 10.1002/j.1460-2075.1989.tb08464.x Pauling, 1991, Effect of ascorbic acid on incidence of spontaneous mammary tumors and UV-light-induced skin tumors in mice, Am. J. Clin. Nutr., 54, 1252S, 10.1093/ajcn/54.6.1252s Peak, 1986, DNA to protein cross links and backbone breaks caused by far and near ultraviolet light and visible radiation in mammalian cells, 193 Ramakrishna-Roa, 1990, Glutathione and ascorbate reduction of the acetaminophen radical formed by peroxidase, J. Biol. Chem., 265, 844, 10.1016/S0021-9258(19)40126-9 Ratnam, 1977, Ascorbic acid and melanogenesis, Br. J. Dermatol., 97, 201, 10.1111/j.1365-2133.1977.tb15066.x Reddy, 1982, Effect of dietary sodium ascorbate on 1,2-dimethylhydrazine or methylnitrosourea-induced colon carcinogenesis in rats, Carcinogenesis, 3, 1097, 10.1093/carcin/3.9.1097 Shacter, 1988, Activated neutrophils induce prolonged DNA damage in neighboring cells, Carcinogenesis, 9, 2297, 10.1093/carcin/9.12.2297 Shapiro, 1967, Reactions of cytosine derivatives with acidic buffer solutions. II. Studies on transamination, deamination and deuterium exchange, 6, 3576 Shapiro, 1966, The deamination of cytidine and cytosine by acidic buffer solutions. Mutagenic implications, 5, 2358 Stahelin, 1987, Plasma vitamin C and cancer death: The prospective Basal study, Vol. 498, 124 Tessman, 1991, The two-step model of ultraviolet mutagenesis reassessed: deamination of cytosine in cyclobutane dimers as the likely source of the mutations associated with photoreactivation, Mol. Gen. Genet., 227, 144, 10.1007/BF00260719 Ullman, 1973, Alkali deamination of cytosine residues in DNA, Biochim. Biophys. Acta, 294, 396, 10.1016/0005-2787(73)90094-4 Varshney, 1991, Specificities and kinetics of uracil excision from uracil-containing DNA oligomers by Escherichia coli uracil DNA glycosylase, Biochemistry, 30, 4055, 10.1021/bi00230a033 Wang, 1982, Heat- and alkali-induced deamination of 5-methylcytosine and cytosine residues in DNA, Biochim. Biophys. Acta, 697, 371, 10.1016/0167-4781(82)90101-4 Weitzman, 1990, Inflammation and cancer: Role of phagocyte-generated oxidants in carcinogenesis, Blood, 76, 655, 10.1182/blood.V76.4.655.655