A mathematical model for the continuous culture of microorganisms utilizing inhibitory substrates

Biotechnology and Bioengineering - Tập 10 Số 6 - Trang 707-723 - 1968
John F. Andrews1
1Environmental Systems Engineering, Clemson University, Clemson, South Carolina 29631

Tóm tắt

AbstractA mathematical model is presented for both batch and continuous cultures of microorganisms utilizing inhibitory substrates. The key feature of the model is the use of a inhibition function to relate substrate concentration and specific growth rate. Simulation studies show that the primary result of inhibition by substrate in a batch culture is an increase in the lag time whereas in continuous culture inhibition by substrate may result in process instability. The model should be of value in investigations of the stability of biological processes used for the treatment of certain industrial wastes such as those containing phenols, thiocyanates, nitrates, ammonia, volatile acids, etc., which are known to be inhibitory to many of the organisms metabolizing them.

Từ khóa


Tài liệu tham khảo

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Thông tin xuất bản

Biotechnology and Bioengineering

Tập 10 Số 6

707-723

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