A look into DGAT1 through the EM lenses

Biochimica et Biophysica Acta (BBA) - Biomembranes - Tập 1865 - Trang 184069 - 2023
Rashmi Panigrahi1, J.N. Mark Glover, Saranya Nallusamy2
1Department of Biochemistry, University of Alberta, Edmonton, Alberta T6G 2H7, Canada
2Department of Plant Molecular Biology and Bioinformatics, Centre for Plant Molecular Biology and Biotechnology, Tamil Nadu Agricultural University, Coimbatore 641003, India

Tài liệu tham khảo

Watson, 2015, Biological membranes, Essays Biochem., 59, 43, 10.1042/bse0590043 Pelley, 2012, 39 Boes, 2021, Peripheral membrane proteins: promising therapeutic targets across domains of life, Membranes, 11, 10.3390/membranes11050346 Klontzas, 2016, Hydroxyapatite deposition disease around the hip: outcomes of CT-guided treatment, Diagn. Interv. Radiol. (Ankara, Turkey), 22, 466, 10.5152/dir.2016.15616 Colović, 2013, Acetylcholinesterase inhibitors: pharmacology and toxicology, Curr. Neuropharmacol., 11, 315, 10.2174/1570159X11311030006 Zhu, 2015, Cisplatin-mediated c-myc overexpression and cytochrome c (cyt c) release result in the up-regulation of the death receptors DR4 and DR5 and the activation of caspase 3 and caspase 9, likely responsible for the TRAIL-sensitizing effect of cisplatin, Med. Oncol. (Northwood, London, England), 32, 133, 10.1007/s12032-015-0588-9 de Planque, 2003, Interfacial anchor properties of tryptophan residues in transmembrane peptides can dominate over hydrophobic matching effects in peptide-lipid interactions, Biochemistry, 42, 5341, 10.1021/bi027000r von Heijne, 1988, Topogenic signals in integral membrane proteins, Eur. J. Biochem., 174, 671, 10.1111/j.1432-1033.1988.tb14150.x Bogdanov, 1843, Lipids and topological rules governing membrane protein assembly, Biochim. Biophys. Acta, 2014, 1475 Lee, 2004, How lipids affect the activities of integral membrane proteins, Biochim. Biophys. Acta, 1666, 62, 10.1016/j.bbamem.2004.05.012 Mancia, 2011, High throughput platforms for structural genomics of integral membrane proteins, Curr. Opin. Struct. Biol., 21, 517, 10.1016/j.sbi.2011.07.001 Love, 2010, The New York consortium on membrane protein structure (NYCOMPS): a high-throughput platform for structural genomics of integral membrane proteins, J. Struct. Funct. Genom., 11, 191, 10.1007/s10969-010-9094-7 Deisenhofer, 1985, Structure of the protein subunits in the photosynthetic reaction centre of Rhodopseudomonas viridis at 3Å resolution, Nature, 318, 618, 10.1038/318618a0 Gallenito, 2022, Studying membrane proteins with MicroED, Biochem. Soc. Trans., 50, 231, 10.1042/BST20210911 Henderson, 1975, Three-dimensional model of purple membrane obtained by electron microscopy, Nature, 257, 28, 10.1038/257028a0 Weiss, 1960, The enzymatic synthesis of triglycerides, J. Biol. Chem., 235, 40, 10.1016/S0021-9258(18)69581-X Lock, 2009, Antisense suppression of type 1 diacylglycerol acyltransferase adversely affects plant development in Brassica napus, Physiol. Plant., 137, 61, 10.1111/j.1399-3054.2009.01258.x Sørensen, 2005, Storage lipid accumulation and acyltransferase action in developing flaxseed, Lipids, 40, 1043, 10.1007/s11745-005-1467-0 Turchetto-Zolet, 2016, Diversity and evolution of plant diacylglycerol acyltransferase (DGATs) unveiled by phylogenetic, gene structure and expression analyses, Genet. Mol. Biol., 39, 524, 10.1590/1678-4685-gmb-2016-0024 Lager, 2020, Acyltransferases regulate oil quality in Camelina sativa through both acyl donor and acyl acceptor specificities, Front. Plant Sci., 11, 1144, 10.3389/fpls.2020.01144 Liu, 2019, Functional characterization of three novel genes encoding diacylglycerol acyltransferase (DGAT) from oil-rich tubers of Cyperus esculentus, Plant Cell Physiol., 61, 118, 10.1093/pcp/pcz184 Caldo, 2017, Diacylglycerol acyltransferase 1 is regulated by its N-terminal domain in response to allosteric effectors, Plant Physiol., 175, 667, 10.1104/pp.17.00934 Aymé, 2018, Arabidopsis thaliana DGAT3 is a [2Fe-2S] protein involved in TAG biosynthesis, Sci. Rep., 8, 17254, 10.1038/s41598-018-35545-7 Jeppson, 2020, A predicted transmembrane region in plant diacylglycerol acyltransferase 2 regulates specificity toward very-long-chain acyl-CoAs, J. Biol. Chem., 295, 15398, 10.1074/jbc.RA120.013755 Yen, 2015, Intestinal triacylglycerol synthesis in fat absorption and systemic energy metabolism, J. Lipid Res., 56, 489, 10.1194/jlr.R052902 Bhatt-Wessel, 2018, Role of DGAT enzymes in triacylglycerol metabolism, Arch. Biochem. Biophys., 655, 1, 10.1016/j.abb.2018.08.001 Kühn, 2004, Evidence for multiple alleles at the DGAT1 locus better explains a quantitative trait locus with major effect on milk fat content in cattle, Genetics, 167, 1873, 10.1534/genetics.103.022749 Chang, 2011, Membrane-bound O-acyltransferases (MBOATs), Front. Biol., 6, 177, 10.1007/s11515-011-1149-z Yang, 2008, Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone, Cell, 132, 387, 10.1016/j.cell.2008.01.017 Masumoto, 2015, Membrane bound O-acyltransferases and their inhibitors, Biochem. Soc. Trans., 43, 246, 10.1042/BST20150018 Panigrahi, 2018, Intrinsic disorder in the regulatory N-terminal domain of diacylglycerol acyltransferase 1 from Brassica napus, Sci. Rep., 8, 16665, 10.1038/s41598-018-34339-1 Sui, 2020, Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme, Nature, 581, 323, 10.1038/s41586-020-2289-6 Wang, 2020, Structure and mechanism of human diacylglycerol O-acyltransferase 1, Nature, 581, 329, 10.1038/s41586-020-2280-2 Caldo, 2015, Purification and properties of recombinant Brassica napus diacylglycerol acyltransferase 1, FEBS Lett., 589, 773, 10.1016/j.febslet.2015.02.008 Torabi, 2021, Effects of type I diacylglycerol O-acyltransferase (DGAT1) genes on soybean (Glycine max L.) seed composition, Sci. Rep., 11, 2556, 10.1038/s41598-021-82131-5 Cheng, 2020, Targeting DGAT1 ameliorates glioblastoma by increasing fat catabolism and oxidative stress, Cell Metab., 32, 229, 10.1016/j.cmet.2020.06.002 Nardi, 2019, DGAT1 inhibitor suppresses prostate tumor growth and migration by regulating intracellular lipids and non-centrosomal MTOC protein GM130, Sci. Rep., 9, 3035, 10.1038/s41598-019-39537-z Huang, 2021, DGAT1 inhibitors protect pancreatic β-cells from palmitic acid-induced apoptosis, Acta Pharmacol. Sin., 42, 264, 10.1038/s41401-020-0482-7 Vujić, 2020, Intestine-specific DGAT1 deficiency improves atherosclerosis in apolipoprotein E knockout mice by reducing systemic cholesterol burden, Atherosclerosis, 310, 26, 10.1016/j.atherosclerosis.2020.07.030 Caldo, 2018, Diacylglycerol acyltransferase 1 is activated by phosphatidate and inhibited by SnRK1-catalyzed phosphorylation, Plant J., 96, 287, 10.1111/tpj.14029