A kinome-wide CRISPR screen identifies CK1α as a target to overcome enzalutamide resistance of prostate cancer

Cell Reports Medicine - Tập 4 - Trang 101015 - 2023
Jinghui Liu1, Yue Zhao2, Daheng He3, Katelyn M. Jones1, Shan Tang2, Derek B. Allison3,4, Yanquan Zhang1, Jing Chen5, Qiongsi Zhang1, Xinyi Wang1, Chaohao Li1, Chi Wang3, Lang Li2, Xiaoqi Liu1,3
1Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY 40536, USA
2Department of Biomedical Informatics, The Ohio State University, Columbus, OH 43210, USA
3Markey Cancer Center, University of Kentucky, Lexington, KY 40536, USA
4Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington, KY 40536, USA
5Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, KY, 40536, USA

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