A <i>Candida albicans</i> CRISPR system permits genetic engineering of essential genes and gene families

Science advances - Tập 1 Số 3 - 2015
Valmik K. Vyas1, M. Inmaculada Barrasa1, Gerald R. Fink2,1
1Whitehead Institute for Biomedical Research, Cambridge, MA 02142 USA
2Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA

Tóm tắt

CRISPR simplifies genetic engineering of the human fungal pathogen Candida albicans .

Từ khóa


Tài liệu tham khảo

10.1128/CMR.00029-06

10.1086/421946

10.1016/j.ijantimicag.2013.09.005

10.1371/journal.pgen.0010001

10.1186/1471-2164-9-579

10.1146/annurev-micro-092611-150111

10.1371/journal.pgen.1000705

10.1128/EC.00060-10

10.1126/science.1128242

10.1111/j.1365-2958.2005.04492.x

10.1038/nature11865

10.1126/science.1258096

10.1016/j.tig.2014.01.003

10.1128/JB.181.20.6339-6346.1999

10.1128/AAC.00926-08

L. E. Cowen, D. Sanglard, S. J. Howard, P. D. Rogers, D. S. Perlin, Mechanisms of antifungal drug resistance. Cold Spring Harb. Perspect. Med. 10.1101/cshperspect.a019752 (2014).

10.1073/pnas.1118859109

10.1128/iai.65.12.4909-4917.1997

10.1128/JB.182.20.5730-5736.2000

J. L. Celenza, M. Carlson, Mutational analysis of the Saccharomyces cerevisiae SNF1 protein kinase and evidence for functional interaction with the SNF4 protein. Mol. Cell. Biol. 9, 5034–5044 (1989).

10.1074/jbc.273.20.12443

10.1093/genetics/98.1.25

10.1128/MCB.22.12.3994-4000.2002

10.1042/bst0310175

10.1128/MCB.23.4.1341-1348.2003

10.1093/nar/gkr945

10.1007/s00294-002-0349-0