A highly efficient site-specific integration strategy using combination of homologous recombination and the ΦC31 integrase

Journal of Biotechnology - Tập 167 - Trang 427-432 - 2013
Hailong Ou1, Ying Huang1,2, Qingwen Ma1,2, Zhaorui Ren1,2, Shuzhen Huang1,2, Fanyi Zeng1,2, Yitao Zeng1,2
1Shanghai Institute of Medical Genetics, Children's Hospital of Shanghai, Shanghai Jiao Tong University School of Medicine, 24/1400 West Beijing Road, Shanghai 200040, China
2Key Lab of Medical Embryo Molecular Biology, Ministry of Health, and Shanghai Lab of Embryo and Reproduction Engineering, Shanghai 200040, China

Tài liệu tham khảo

Beumer, 2008, Efficient gene targeting in Drosophila by direct embryo injection with zinc-finger nucleases, Proc. Natl. Acad. Sci. U.S.A., 105, 19821, 10.1073/pnas.0810475105 Cathomen, 2008, Zinc-finger nucleases: the next generation emerges, Mol. Ther., 16, 1200, 10.1038/mt.2008.114 Chavez, 2012, Long-term expression of human coagulation factor VIII in a tolerant mouse model using the C31 Φintegrase system, Hum. Gene Ther., 23, 390, 10.1089/hum.2011.110 Cristea, 2012, In vivo cleavage of transgene donors promotes nuclease-mediated targeted integration, Biotechnol. Bioeng. Gopalakrishnan, 2012, Targeted disruption of Adamts16 gene in a rat genetic model of hypertension, Proc. Natl. Acad. Sci. U.S.A., 109, 20555, 10.1073/pnas.1211290109 Gupta, 2011, Zinc finger protein dependent and independent contributions to the in vivo off-target activity of zinc finger nucleases, Nucleic Acids Res., 39, 381, 10.1093/nar/gkq787 Hu, 2011, ΦC31 integrase mediates efficient cassette exchange in the zebrafish germline, Dev. Dyn., 240, 2101, 10.1002/dvdy.22699 Kandavelou, 2009, Custom-designed molecular scissors for site-specific manipulation of the plant and mammalian genomes, Methods Mol. Biol., 544, 617, 10.1007/978-1-59745-483-4_40 Kempe, 2010, Transgene excision from wheat chromosomes by phage phiC31 integrase, Plant Mol. Biol., 72, 673, 10.1007/s11103-010-9606-7 Kim, 1996, Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain, Proc. Natl. Acad. Sci. U.S.A., 93, 1156, 10.1073/pnas.93.3.1156 Li, 2011, TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain, Nucleic Acids Res., 39, 359, 10.1093/nar/gkq704 Ma, 2006, Identification of pseudo attP sites for phage phiC31 integrase in bovine genome, Biochem. Biophys. Res. Commun., 345, 984, 10.1016/j.bbrc.2006.04.145 Ou, 2009, A phiC31 integrase-mediated integration hotspot in favor of transgene expression exists in the bovine genome, FASEB J., 276, 155 Pattanayak, 2011, Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection, Nat. Methods, 8, 765, 10.1038/nmeth.1670 Petek, 2010, Frequent endonuclease cleavage at off-target locations in vivo, Mol. Ther., 18, 983, 10.1038/mt.2010.35 Qu, 2012, A profile of native integration sites used by ΦC31 integrase in the bovine genome, J. Genet. Genomics, 39, 217, 10.1016/j.jgg.2012.03.004 Rouet, 1994, Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells, Proc. Natl. Acad. Sci. U.S.A., 91, 6064, 10.1073/pnas.91.13.6064 Tesson, 2011, Knockout rats generated by embryo microinjection of TALENs, Nat. Biotechnol., 29, 695, 10.1038/nbt.1940 Thyagarajan, 2001, Site-specific genomic integration in mammalian cells mediated by phage phiC31 integrase, Mol. Cell Biol., 21, 3926, 10.1128/MCB.21.12.3926-3934.2001 Townsend, 2009, High-frequency modification of plant genes using engineered zinc-finger nucleases, Nature, 459, 442, 10.1038/nature07845 Urnov, 2005, Highly efficient endogenous human gene correction using designed zinc-finger nucleases, Nature, 435, 646, 10.1038/nature03556 van der Weyden, 2002, Tools for targeted manipulation of the mouse genome, Physiol. Genomics, 11, 133, 10.1152/physiolgenomics.00074.2002 Vasquez, 2001, Manipulating the mammalian genome by homologous recombination, Proc. Natl. Acad. Sci. U.S.A., 98, 8403, 10.1073/pnas.111009698 Venken, 2011, MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes, Nat. Methods, 8, 737, 10.1038/nmeth.1662 Wood, 2011, Targeted genome editing across species using ZFNs and TALENs, Science, 33, 307, 10.1126/science.1207773 Zhang, 2011, Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription, Nat. Biotechnol., 29, 149, 10.1038/nbt.1775 Zhang, 2010, High frequency targeted mutagenesis in Arabidopsis thaliana using zinc finger nucleases, Proc. Natl. Acad. Sci. U.S.A., 107, 12028, 10.1073/pnas.0914991107