A gel microparticle-based self-thickening strategy for 3D printing high-modulus hydrogels skeleton cushioned with PNAGA hydrogel mimicking anisotropic mechanics of meniscus

Wolf, 2020, Degenerative meniscus tear in older athletes, Clin. Sports Med., 39, 197, 10.1016/j.csm.2019.08.005 Mcclain, 2021, Meniscus repair techniques, Sports Med. Arthrosc., 29, 34, 10.1097/JSA.0000000000000320 Messner, 1993, The concept of a permanent synthetic meniscus prothesis: a critical discussion after 5 years of experimental investigation using Decron and Teflon implants, Biomaterials, 15, 243, 10.1016/0142-9612(94)90046-9 Sommerlath, 1992, Biomechanical characteristics of different artificial substitutes for rabbit medial meniscus and effect of prosthesis size on knee cartilage, Clin. Biomech., 7, 97, 10.1016/0268-0033(92)90022-V Tienen, 2006, Replacement of the knee meniscus by a porour polymer implant: a study in dogs, Am. J. Sports Med., 34, 64, 10.1177/0363546505280905 Klompmaker, 1993, Porous implants for knee joint meniscus reconstruction: a preliminary study on the role of pore sizes in ingrowth and differentiation of fibrocartilage, Clin. Mater., 14, 1, 10.1016/0267-6605(93)90041-5 Tienen, 2006, Meniscal replacement in dogs. Tissue regeneration in two different materials with similar properties, J. Biomed. Mater. Res. B Appl. Biomater., 76B, 389, 10.1002/jbm.b.30406 Welsing, 2008, Effect on tissue differentiation and articular cartilage degradation of a polymer meniscus implant: a 2-year follow-up study in dogs, Am. J. Sports Med., 36, 1978, 10.1177/0363546508319900 Kobayashi, 2003, Development of an artificial meniscus using polyvinyl alcohol-hydrogel for early return to, and continuance of, athletic life in sportspersons with severe meniscus injury. I: mechanical evaluation, Knee, 10, 47, 10.1016/S0968-0160(02)00152-7 Kobayashi, 2003, Preliminary study of polyvinyl alcohol-hydrogel (PVA-H) artificial meniscus, Biomaterials, 24, 639, 10.1016/S0142-9612(02)00378-2 Kobayashi, 2005, A two year in vivo study of polyvinyl alcohol-hydrogel (PVA-H) artificial meniscus, Biomaterials, 26, 3243, 10.1016/j.biomaterials.2004.08.028 Kelly, 2007, Hydrogel meniscal replacement in the sheep knee: preliminary evaluation of chondroprotective effects, Am. J. Sports Med., 35, 43, 10.1177/0363546506292848 Elsner, 2010, Design of a free-floating polycarbonate-urethane meniscal implant using finite element modeling and experimental validation, J. Biomech. Eng., 132, 10.1115/1.4001892 Zur, 2011, Chondroprotective effects of a polycarbonate-urethane meniscal implant: histopathological results in a sheep model, Knee Surg. Sports Traumatol. Arthrosc., 19, 255, 10.1007/s00167-010-1210-5 Holloway, 2010, Mechanical evaluation of poly(vinyl alcohol)-based fibrous composites as biomaterials for meniscal tissue replacement, Acta Biomater., 6, 4716, 10.1016/j.actbio.2010.06.025 Li, 2017, Micromechanical anisotropy and heterogeneity of the meniscus extracellular matrix, Acta Biomater., 54, 356, 10.1016/j.actbio.2017.02.043 Danso, 2017, Structure-function relationships of human meniscus, J. Mech. Behav. Biomed. Mater., 67, 51, 10.1016/j.jmbbm.2016.12.002 Yanagishita, 1993, Function of proteoglycans in the extracellular matrix, Acta Pathol. Jpn., 43, 283 Dai, 2015, A mechanically strong, highly stable, thermoplastic, and self-healable supramolecular polymer hydrogel, Adv. Mater., 27, 3566, 10.1002/adma.201500534 Fan, 2020, Polymerization of N-acryloylsemicarbazide: a facile and versatile strategy to tailor-make highly stiff and tough hydrogels, Mater. Horiz., 7, 1160, 10.1039/C9MH01844A Gao, 2016, Sea cucumber-inspired autolytic hydrogels exhibiting tunable high mechanical performances, repairability, and reusability, ACS Appl. Mater. Interfaces, 8, 8956, 10.1021/acsami.6b00912 Yu, 2021, An ultrasoft self-fused supramolecular polymer hydrogel for completely preventing postoperative tissue adhesion, Adv. Mater., 33, 10.1002/adma.202008395 Cui, 2018, An autolytic high strength instant adhesive hydrogel for emergency self-rescue, Adv. Funct. Mater., 28, 10.1002/adfm.201804925 Zhang, 2022, 3D printed high-strength supramolecular polymer hydrogel-cushioned radially and circumferentially oriented meniscus substitute, Adv. Funct. Mater., 32 Yang, 2021, 3D printing stiff antibacterial hydrogels for meniscus replacement, Appl. Mater. Today, 24 Fan, 2021, 3D printing of lubricative stiff supramolecular polymer hydrogels for meniscus replacement, Biomater. Sci., 9, 5116, 10.1039/D1BM00836F Xu, 2021, A self-thickening and self-strengthening strategy for 3D printing high-strength and antiswelling supramolecular polymer hydrogels as meniscus substitutes, Adv. Funct. Mater., 31 Li, 2022, An intermediate unit-mediated, continuous structural inheritance strategy for the dilemma between injectability and robustness of hydrogels, Adv. Funct. Mater., 32 Zhang, 2020, Direct 3D printed biomimetic scaffolds based on hydrogel microparticles for cell spheroid growth, Adv. Funct. Mater., 30 Song, 2020, Injectable gelatin microgel-based composite ink for bioprinting in air, ACS Appl. Mater. Interfaces, 12, 22453, 10.1021/acsami.0c01497 Pritzker, 2006, Osteoarthritis cartilage histopathology: grading and staging, Osteoarthritis Cartilage, 14, 13, 10.1016/j.joca.2005.07.014 Xu, 2018, Poly(N-acryloyl glycinamide): a fascinating polymer that exhibits a range of properties from UCST to high-strength hydrogels, Chem. Commun., 54, 10540, 10.1039/C8CC04614J Sinclair, 2018, Self-healing zwitterionic microgels as a versatile platform for malleable cell constructs and injectable therapies, Adv. Mater., 30 Hirsch, 2021, 3D printing of strong and tough double network granular hydrogel, Adv. Funct. Mater., 31, 10.1002/adfm.202005929 Zhao, 2021, 3D printing method for tough multifunctional particle-based double-network hydrogel, ACS Appl. Mater. Interfaces, 13, 13714, 10.1021/acsami.1c01413 Gao, 2018, Direct 3D printing of high strength biohybrid gradient hydrogel scaffolds for efficient repair of osteochondral defect, Adv. Funct. Mater., 28, 10.1002/adfm.201706644 Holloway, 2014, Interfacial optimization of fiber-reinforced hydrogel composites for soft fibrous tissue applications, Acta Biomater., 10, 3581, 10.1016/j.actbio.2014.05.004 Zhu, 2016, 3D printing of ultratough polyion complex hydrogels, ASC Appl. Mater. Interfaces, 8, 31304, 10.1021/acsami.6b09881 Bakarich, 2013, Extrusion printing of ionic-covalent entanglement hydrogels with high toughness, J. Mater. Chem. B, 38, 4939, 10.1039/c3tb21159b Lechner, 2000, Is the circumferential tensile modulus within a human medial meniscus affected by the test sample location and cross-sectional area?, J. Orthop. Res., 18, 945, 10.1002/jor.1100180614 Bahcecioglu, 2019, A 3D printed PCL/hydrogel construct with zone-specific biochemical composition mimicking that of the meniscus, Biofabrication, 11, 10.1088/1758-5090/aaf707 Li, 2020, Cell-free 3D wet-electrospun PCL/silk fibroin/Sr2+ scaffold promotes successful total meniscus regeneration in a rabbit model, Acta Biomater., 113, 196, 10.1016/j.actbio.2020.06.017