A dosimetric uncertainty analysis for photon‐emitting brachytherapy sources: Report of AAPM Task Group No. 138 and GEC‐ESTRO

Medical Physics - Tập 38 Số 2 - Trang 782-801 - 2011
Larry A. DeWerd1, Geoffrey S. Ibbott2, Ali S. Meigooni3, Michael G. Mitch4, Mark J. Rivard5,6, Kurt E. Stump7, Bruce Thomadsen8, Jack Venselaar9
1Department of Medical Physics and Accredited Dosimetry Calibration Laboratory, University of Wisconsin, Madison, Wisconsin 53706
2Department of Radiation Physics, M. D. Anderson Cancer Center, Houston, Texas 77030
3Department of Radiation Oncology, Comprehensive Cancer Center of Nevada, Las Vegas, Nevada 89169
4Ionizing Radiation Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899
5Department of Radiation Oncology, Tufts University School of Medicine, Boston, Massachusetts 02111
6Electronic mail: [email protected]
7Santa Maria Radiation Oncology Center, Santa Maria, California 93454
8Departments of Medical Physics and Human Oncology, University of Wisconsin, Madison, Wisconsin 53706
9Department of Medical Physics and Engineering, Instituut Verbeeten, 5042 SB Tilburg, The Netherlands

Tóm tắt

This report addresses uncertainties pertaining to brachytherapy single‐source dosimetry preceding clinical use. The International Organization for Standardization (ISO) Guide to the Expression of Uncertainty in Measurement (GUM) and the National Institute of Standards and Technology (NIST) Technical Note 1297 are taken as reference standards for uncertainty formalism. Uncertainties in using detectors to measure or utilizing Monte Carlo methods to estimate brachytherapy dose distributions are provided with discussion of the components intrinsic to the overall dosimetric assessment. Uncertainties provided are based on published observations and cited when available. The uncertainty propagation from the primary calibration standard through transfer to the clinic for air‐kerma strength is covered first. Uncertainties in each of the brachytherapy dosimetry parameters of the TG‐43 formalism are then explored, ending with transfer to the clinic and recommended approaches. Dosimetric uncertainties during treatment delivery are considered briefly but are not included in the detailed analysis. For low‐ and high‐energy brachytherapy sources of low dose rate and high dose rate, a combined dosimetric uncertainty is estimated, which is consistent with prior literature estimates. Recommendations are provided for clinical medical physicists, dosimetry investigators, and source and treatment planning system manufacturers. These recommendations include the use of the GUM and NIST reports, a requirement of constancy of manufacturer source design, dosimetry investigator guidelines, provision of the lowest uncertainty for patient treatment dosimetry, and the establishment of an action level based on dosimetric uncertainty. These recommendations reflect the guidance of the American Association of Physicists in Medicine (AAPM) and the Groupe Européen de Curiethérapie–European Society for Therapeutic Radiology and Oncology (GEC‐ESTRO) for their members and may also be used as guidance to manufacturers and regulatory agencies in developing good manufacturing practices for sources used in routine clinical treatments.

Từ khóa


Tài liệu tham khảo

10.1118/1.597316

10.1118/1.1646040

10.1118/1.597458

10.1118/1.2736790

Honsa J. D., 2003, ISO 17025: Practical benefits of implementing a quality system, J. AOAC Int., 86, 1038, 10.1093/jaoac/86.5.1038

10.1136/bmj.322.7280.226

10.1118/1.3125136

10.1088/0026‐1394/17/2/007

Evaluation of measurement data—Guide to the expression of uncertainty in measurement International Organization for Standardization(ISO) Joint Committee for Guides in Metrology (JCGM 100 2008) corrected version 2010 http://www.bipm.org/utils/common/documents/jcgm/JCGM_100_2008_E.pdf(last accessed December 5 2010).

B. N.TaylorandC. E.Kuyatt “Guidelines for evaluating and expressing the uncertainty of NIST measurement results ” NIST Technical Note 1297 (U.S. Government Printing Office Washington DC 1994) http://physics.nist.gov/Pubs/guidelines/contents.html(last accessed December 5 2010).

10.1118/1.1781552

10.13182/NSE05-A2480

10.1118/1.2760372

10.1118/1.2968097

10.1118/1.3020754

10.1016/S1538‐4721(02)00015‐6

10.1088/0031‐9155/44/10/406

DeWerd L. A., 2009, Clinical Dosimetry for Radiotherapy: AAPM Summer School, 815

10.1118/1.3429089

10.1118/1.596630

Saylor M. C., 1988, A thin film recording medium for use in food irradiation, Radiat. Phys. Chem., 31, 529

10.1118/1.597245

10.1120/jacmp.2023.25329

10.1118/1.3121488

10.1118/1.598407

Soares C. G., 2009, Clinical Dosimetry for Radiotherapy: AAPM Summer School, 759

10.1097/00004032‐200206000‐00017

10.1118/1.3291622

10.1118/1.3373523

10.1118/1.3378675

10.1118/1.2357019

10.1118/1.3253902

10.1088/0031‐9155/47/16/308

Williamson J. F., 2005, Brachytherapy Physics: Joint AAPM/ABS Summer School, 233

E.Yorkeet al. “Diode in vivo dosimetry for patients receiving external beam radiation therapy: Report of Task Group 62 of the Radiation Therapy Committee ” AAPM Report No. 87 (Medical Physics Publishing Madison WI 2005).

10.1118/1.2198168

10.1016/S0360‐3016(96)00600‐1

10.1016/j.radonc.2006.07.008

10.1016/j.ijrobp.2008.08.040

10.1118/1.1384460

R. A. Koona 2005 University of Kentucky

10.1118/1.1355306

10.1118/1.2432162

10.1118/1.597791

10.1118/1.2357021

10.1118/1.1809851

10.1118/1.3298008

10.1118/1.1395038

10.1118/1.1493780

10.1118/1.3194754

NUDAT 2.5 National Nuclear Data Center Brookhaven National Laboratory Upton NY USA http://www.nndc.bnl.gov/nudat2/index.jsp(last accessed December 5 2010).

10.1118/1.1759826

10.1118/1.2199987

10.1118/1.2965360

10.1118/1.2357018

10.1118/1.1388218

10.1118/1.2987676

10.1088/0031‐9155/47/8/307

Cullen D. E., 1997, EPDL97: The Evaluated Photon Data Library, '97 Version, Lawrence Livermore National Laboratory, 6

10.2307/3578607

10.1118/1.596069

10.1118/1.3121510

10.6028/jres.108.030

Mitch M. G., 2009, Clinical Dosimetry for Radiotherapy: AAPM Summer School, 549

10.1088/0026‐1394/46/2/S06

10.1088/0026‐1394/45/4/007

10.6028/jres.085.003

10.1118/1.2388155

10.6028/jres.074A.001

10.1118/1.597966

10.1118/1.596649

10.1118/1.2239198

10.1118/1.1791352

10.1118/1.1487860

10.1088/0031‐9155/55/11/011

10.1088/0031‐9155/50/9/003

10.1088/0031‐9155/53/6/N02

10.1118/1.1645681

10.1118/1.2959723

10.1118/1.1496099

10.1118/1.1496100

10.1118/1.3429131

10.1016/S1040‐8428(03)00026‐X

10.1118/1.3360441

Thông tin
Thông tin xuất bản

Medical Physics

Tập 38 Số 2

782-801

Thông tin tác giả