A defined glycosaminoglycan-binding substratum for human pluripotent stem cells

Thomson, J.A. et al. Embryonic stem cell lines derived from human blastocysts. Science 282, 1145–1147 (1998).

Takahashi, K. et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861–872 (2007).

Yu, J. et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 318, 1917–1920 (2007).

Ludwig, T.E. et al. Derivation of human embryonic stem cells in defined conditions. Nat. Biotechnol. 24, 185–187 (2006).

Yao, S. et al. Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions. Proc. Natl. Acad. Sci. USA 103, 6907–6912 (2006).

Wang, L. et al. Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling. Blood 110, 4111–4119 (2007).

Xu, C. et al. Feeder-free growth of undifferentiated human embryonic stem cells. Nat. Biotechnol. 19, 971–974 (2001).

Martin, M.J., Muotri, A., Gage, F. & Varki, A. Human embryonic stem cells express an immunogenic nonhuman sialic acid. Nat. Med. 11, 228–232 (2005).

Amit, M., Shariki, C., Margulets, V. & Itskovitz-Eldor, J. Feeder layer- and serum-free culture of human embryonic stem cells. Biol. Reprod. 70, 837–845 (2004).

Braam, S.R. et al. Recombinant vitronectin is a functionally defined substrate that supports human embryonic stem cell self renewal via alphavbeta5 integrin. Stem Cells 26, 2257–2265 (2008).

Vuoristo, S. et al. Laminin isoforms in human embryonic stem cells: synthesis, receptor usage and growth support. J. Cell. Mol. Med. 13, 2622–2633 (2009).

Derda, R. et al. Defined substrates for human embryonic stem cell growth identified from surface arrays. ACS Chem. Biol. 2, 347–355 (2007).

Gerecht, S. et al. Hyaluronic acid hydrogel for controlled self-renewal and differentiation of human embryonic stem cells. Proc. Natl. Acad. Sci. USA 104, 11298–11303 (2007).

Li, Y.J., Chung, E.H., Rodriguez, R.T., Firpo, M.T. & Healy, K.E. Hydrogels as artificial matrices for human embryonic stem cell self-renewal. J. Biomed. Mater. Res. A 79, 1–5 (2006).

Harb, N., Archer, T.K. & Sato, N. The Rho-Rock-Myosin signaling axis determines cell-cell integrity of self-renewing pluripotent stem cells. PLoS ONE 3, e3001 (2008).

Melkoumian, Z. et al. Synthetic peptide-acrylate surfaces for long-term self-renewal and cardiomyocyte differentiation of human embryonic stem cells. Nat. Biotechnol. 28, 606–610 (2010).

Villa-Diaz, L.G. et al. Synthetic polymer coatings for long-term growth of human embryonic stem cells. Nat. Biotechnol. 28, 581–583 (2010).

Derda, R. et al. High-throughput discovery of synthetic surfaces that support proliferation of pluripotent cells. J. Am. Chem. Soc. 132, 1289–1295 (2010).

Meng, Y. et al. Characterization of integrin engagement during defined human embryonic stem cell culture. FASEB J. 24, 1056–1065 (2010).

Kolhar, P., Kotamraju, V.R., Hikita, S.T., Clegg, D.O. & Ruoslahti, E. Synthetic surfaces for human embryonic stem cell culture. J. Biotechnol. 146, 143–146 (2010).

Orner, B.P., Derda, R., Lewis, R.L., Thomson, J.A. & Kiessling, L.L. Arrays for the combinatorial exploration of cell adhesion. J. Am. Chem. Soc. 126, 10808–10809 (2004).

Whitesides, G.M., Ostuni, E., Takayama, S., Jiang, X. & Ingber, D.E. Soft lithography in biology and biochemistry. Annu. Rev. Biomed. Eng. 3, 335–373 (2001).

Mrksich, M. & Whitesides, G.M. Using self-assembled monolayers to understand the interactions of man-made surfaces with proteins and cells. Annu. Rev. Bioph. Biom. 25, 55–78 (1996).

Ruoslahti, E. & Pierschbacher, M.D. New perspectives in cell adhesion: RGD and integrins. Science 238, 491–497 (1987).

Lutolf, M.P., Gilbert, P.M. & Blau, H.M. Designing materials to direct stem-cell fate. Nature 462, 433–441 (2009).

Watanabe, K. et al. A ROCK inhibitor permits survival of dissociated human embryonic stem cells. Nat. Biotechnol. 25, 681–686 (2007).

Vogel, B.E. et al. A novel integrin specificity exemplified by binding of the alpha v beta 5 integrin to the basic domain of the HIV Tat protein and vitronectin. J. Cell Biol. 121, 461–468 (1993).

Bishop, J.R., Schuksz, M. & Esko, J.D. Heparan sulphate proteoglycans fine-tune mammalian physiology. Nature 446, 1030–1037 (2007).

Ying, Q.L. et al. The ground state of embryonic stem cell self-renewal. Nature 453, 519–523 (2008).

Engler, A.J., Sen, S., Sweeney, H.L. & Discher, D.E. Matrix elasticity directs stem cell lineage specification. Cell 126, 677–689 (2006).

Ludwig, T.E. et al. Feeder-independent culture of human embryonic stem cells. Nat. Methods 3, 637–646 (2006).

Prokhorova, T. et al. Teratoma formation by human embryonic stem cells is site-dependent and enhanced by the presence of Matrigel. Stem Cells Dev. 18, 47–54 (2008).

Laflamme, M.A. et al. Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat. Biotechnol. 25, 1015–1024 (2007).

D'Amour, K.A. et al. Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat. Biotechnol. 23, 1534–1541 (2005).

Chambers, S.M. et al. Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat. Biotechnol. 27, 275–280 (2009).

Luk, Y.Y., Kato, M. & Mrksich, M. Self-assembled monolayers of alkanethiolates presenting mannitol groups are inert to protein adsorption and cell attachment. Langmuir 16, 9604–9608 (2000).

Klein, E.A., Yung, Y., Castagnino, P., Kothapalli, D. & Assoian, R.K. Cell adhesion, cellular tension, and cell cycle control. Methods Enzymol. 426, 155–175 (2007).