A complementary diffusion tensor imaging (DTI)-histological study in a model of Huntington's disease

Acosta-Cabronero, 2010, Absolute diffusivities define the landscape of white matter degeneration in Alzheimer's disease, Brain, 133, 529, 10.1093/brain/awp257 Aguilera, 2007, Time-related changes in constitutive and inducible nitric oxide synthases in the rat striatum in a model of Huntington's disease, Neurotoxicology, 28, 1200, 10.1016/j.neuro.2007.07.010 Alexander, 2007, Diffusion tensor imaging of the brain, Neurotherapeutics, 4, 316, 10.1016/j.nurt.2007.05.011 Araujo, 2000, Deficits in striatal dopamine D(2) receptors and energy metabolism detected by in vivo microPET imaging in a rat model of Huntington's disease, Exp. Neurol., 166, 287, 10.1006/exnr.2000.7514 Basser, 1994, Estimation of the effective self-diffusion tensor from the NMR spin echo, J. Magn. Reson. B, 103, 247, 10.1006/jmrb.1994.1037 Beal, 1991, Chronic quinolinic acid lesions in rats closely resemble Huntington disease, J. Neurosci., 11, 1649, 10.1523/JNEUROSCI.11-06-01649.1991 Bohanna, 2008, Magnetic resonance imaging as an approach towards identifying neuropathological biomarkers for Huntington disease, Brain Res. Rev., 58, 209, 10.1016/j.brainresrev.2008.04.001 Brouillet, 1999, Replicating Huntington disease phenotype in experimental animals, Prog. Neurobiol., 59, 427, 10.1016/S0301-0082(99)00005-2 Budde, 2009, Axial diffusivity is the primary correlate of axonal injury in the experimental autoimmune encephalomyelitis spinal cord: a quantitative pixelwise analysis, J. Neurosci., 29, 2805, 10.1523/JNEUROSCI.4605-08.2009 D'Agostino, 2003, A viscous fluid model for multimodal non-rigid image registration using mutual information, Med. Image Anal., 7, 565, 10.1016/S1361-8415(03)00039-2 Douaud, 2009, In vivo evidence for the selective subcortical degeneration in Huntington's disease, Neuroimage, 46, 958, 10.1016/j.neuroimage.2009.03.044 Estrada Sanchez, 2008, Excitotoxic neuronal death and the pathogenesis of Huntington's disease, Arch. Med. Res., 39, 265, 10.1016/j.arcmed.2007.11.011 Fennema-Notestine, 2004, In vivo evidence of cerebellar atrophy and cerebral white matter loss in Huntington disease, Neurology, 63, 989, 10.1212/01.WNL.0000138434.68093.67 Ferrante, 1993, Excitotoxin lesions in primates as a model for Huntington disease: histopathologic and neurochemical characterization, Exp. Neurol., 119, 46, 10.1006/exnr.1993.1006 Gimenez-Llort, 1998, Analysis of chemically induced alterations of the motor activity in rats, Neurotoxicology, 19, 371 Gimenez-Llort, 1995, Effects of the systemic administration of kainic acid and NMDA on exploratory activity in rats, Pharmacol. Biochem. Behav., 51, 205, 10.1016/0091-3057(94)00420-N Kim, 2006, Detecting axon damage in spinal cord from a mouse model of multiple sclerosis, Neurobiol. Dis., 21, 626, 10.1016/j.nbd.2005.09.009 Kloppel, 2008, White matter connections reflect changes in voluntary-guided saccades in pre-symptomatic Huntington disease, Brain, 131, 196, 10.1093/brain/awm275 Maes, 1997, Multimodality image registration by maximization of mutual information, IEEE Trans. Med. Imaging, 16, 187, 10.1109/42.563664 Marrannes, 1988, Episodic barrel rotations induced by intrastriatal injection of quinolinic acid in rats, Pharmacol. Biochem. Behav., 31, 153, 10.1016/0091-3057(88)90327-9 Moresco, 2008, Quinolinic acid induced neurodegeneration in the striatum: a combined in vivo and in vitro analysis of receptor changes and microglia activation, Eur. J. Nucl. Med. Mol. Imaging, 35, 704, 10.1007/s00259-007-0651-7 Nicholson, 1995, GABA and GABAA receptor changes in the substantia nigra of the rat following quinolinic acid lesions in the striatum closely resemble Huntington disease, Neuroscience, 66, 507, 10.1016/0306-4522(94)00607-7 Paxinos, 2006 Roberts, 1993, Intrastriatal Injections of Quinolinic Acid or Kainic Acid: Differential Patterns of Cell Survival and the Effects of Data Analysis on Outcome, Exp. Neurol., 124, 274, 10.1006/exnr.1993.1197 Rosas, 2006, Diffusion tensor imaging in presymptomatic and early Huntington disease: Selective white matter pathology and its relationship to clinical measures, Mov. Disord., 21, 1317, 10.1002/mds.20979 Rosas, 2010, Altered white matter microstructure in the corpus callosum in Huntington's disease: Implications for cortical “disconnection”, Neuroimage, 49, 2995, 10.1016/j.neuroimage.2009.10.015 Salat, 2010, White matter pathology isolates the hippocampal formation in Alzheimer's disease, Neurobiol. Aging, 31, 244, 10.1016/j.neurobiolaging.2008.03.013 Sapp, 2001, Early and progressive accumulation of reactive microglia in the Huntington disease brain, J. Neuropathol. Exp. Neurol., 60, 161, 10.1093/jnen/60.2.161 Scattoni, 2004, Progressive behavioural changes in the spatial open-field in the quinolinic acid rat model of Huntington's disease, Behav. Brain Res., 152, 375, 10.1016/j.bbr.2003.10.021 Schwarcz, 1984, Excitotoxic models for neurodegenerative disorders, Life Sci., 35, 19, 10.1016/0024-3205(84)90148-6 Schwarcz, 2009, Of mice, rats and men: Revisiting the quinolinic acid hypothesis of Huntington's disease, Prog. Neurobiol., 90, 230, 10.1016/j.pneurobio.2009.04.005 Shear, 1998, Comparison of intrastriatal injections of quinolinic acid and 3-nitropropionic acid for use in animal models of Huntington's disease, Prog. Neuropsychopharmacol. Biol. Psychiatry, 22, 1217, 10.1016/S0278-5846(98)00070-0 Song, 2004, Diffusion tensor imaging detects age-dependent white matter changes in a transgenic mouse model with amyloid deposition, Neurobiol. Dis., 15, 640, 10.1016/j.nbd.2003.12.003 Song, 2003, Diffusion tensor imaging detects and differentiates axon and myelin degeneration in mouse optic nerve after retinal ischemia, Neuroimage, 20, 1714, 10.1016/j.neuroimage.2003.07.005 Stoffers, 2010, Contrasting gray and white matter changes in preclinical Huntington disease: an MRI study, Neurology, 74, 1208, 10.1212/WNL.0b013e3181d8c20a Sun, 2006, Noninvasive detection of cuprizone induced axonal damage and demyelination in the mouse corpus callosum, Magn. Reson. Med., 55, 302, 10.1002/mrm.20774 Sun, 2005, Detection of age-dependent brain injury in a mouse model of brain amyloidosis associated with Alzheimer's disease using magnetic resonance diffusion tensor imaging, Exp. Neurol., 191, 77, 10.1016/j.expneurol.2004.09.006 Tai, 2007, Imaging microglial activation in Huntington's disease, Brain Res. Bull., 72, 148, 10.1016/j.brainresbull.2006.10.029 Tai, 2007, Microglial activation in presymptomatic Huntington disease gene carriers, Brain, 130, 1759, 10.1093/brain/awm044 1993, A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington disease chromosomes, Cell, 72, 971, 10.1016/0092-8674(93)90585-E Thieben, 2002, The distribution of structural neuropathology in pre-clinical Huntington disease, Brain, 125, 1815, 10.1093/brain/awf179 Underwood, 2006, Huntington disease patients and transgenic mice have similar pro-catabolic serum metabolite profiles, Brain, 129, 877, 10.1093/brain/awl027 Van Camp, 2009, Diffusion Tensor Imaging in a Rat Model of Parkinson's Disease After Lesioning of the Nigrostriatal Tract, NMR Biomed., 22, 697, 10.1002/nbm.1381 Van Hecke, 2007, Nonrigid coregistration of diffusion tensor images using a viscous fluid model and mutual information, IEEE Trans. Med. Imaging, 26, 1598, 10.1109/TMI.2007.906786 Van Hecke, 2009, On the construction of a ground truth framework for evaluating voxel-based diffusion tensor MRI analysis methods, Neuroimage, 46, 692, 10.1016/j.neuroimage.2009.02.032 Vivo, 2002, Lesion of substantia nigra pars compacta by the GluR5 agonist ATPA, Brain Res., 955, 104, 10.1016/S0006-8993(02)03373-5 Vonsattel, 1998, Huntington disease, J. Neuropathol. Exp. Neurol., 57, 369, 10.1097/00005072-199805000-00001 Vymazal, 2007, MR relaxometry in Huntington's disease: correlation between imaging, genetic and clinical parameters, J. Neurol. Sci., 263, 20, 10.1016/j.jns.2007.05.018 Weaver, 2009, Longitudinal diffusion tensor imaging in Huntington's Disease, Exp. Neurol., 216, 525, 10.1016/j.expneurol.2008.12.026 Xu, 2008, Assessing optic nerve pathology with diffusion MRI: from mouse to human, NMR Biomed., 21, 928, 10.1002/nbm.1307