A comparison of mutational specificity of mutations induced by S9-activated B[a]P and benzo[a]pyrene-7,8-diol-9,10-epoxide at the endogenous aprt gene in CHO cells

Haiyan Yang1, Mary Mazur-Melnyk2, Johan G. de Boer1, Barry W. Glickman1
1Centre for Environmental Health, University of Victoria, Victoria, British Columbia, Canada V8W 3N5
2Connaught Laboratories, 1755 Steeles Avenue West, Willowdale, Ontario, Canada M2R 3T4

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Adams, 1987, Statistical test for the comparison of samples from mutational spectra, J. Mol. Biol., 194, 391, 10.1016/0022-2836(87)90669-3

Andersson, 1992, Strand specificity for mutations induced by (+)-anti BPDE in the hprt gene in human T-lymphocytes, Mutat. Res., 269, 129, 10.1016/0027-5107(92)90168-2

Baer-Dubowska, 1981, The binding of benzo[a]pyrene to mouse and rat skin DNA, Cancer Letters, 13, 47, 10.1016/0304-3835(81)90085-9

Bradley, 1982, High-frequency nonrandom mutational event at the adenine phosphoribosyl transferase (aprt) locus of sib-selected CHO variants heterozygous for aprt, Somatic Cell Genet., 8, 51, 10.1007/BF01538650

Brown, 1986, Structural characterization of the bromouracil.guanine base pair mismatch in a Z-DNA fragment, Nucleic. Acids. Res., 14, 1801, 10.1093/nar/14.4.1801

Brown, 1989, Crystal structure and stability of a DNA duplex containing A(anti). G(syn) base-pairs, J. Mol. Biol., 207, 455, 10.1016/0022-2836(89)90268-4

Buening, 1978, Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene-7,8-diol-9,10-epoxides in newborn mice, exceptional activity of (+)-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene, Proc. Natl. Acad. Sci., 75, 5358, 10.1073/pnas.75.11.5358

Chary, 1995, In vivo and in vitro replication consequences of stereoisomeric benzo[a]pyrene-7,8-dihydrodiol 9,10-epoxide adducts on adenine N6 at the second position of N-ras codon 61, J. Biol. Chem., 270, 4990, 10.1074/jbc.270.10.4990

Chen, 1990, Effect of excision repair by diploid human fibroblasts on the kinds and locations of mutations induced by (±)-7-beta,8-alpha-dihydroxy-9-alpha,10-alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in the coding region of the HPRT gene, Proc. Natl. Acad. Sci. USA, 87, 8680, 10.1073/pnas.87.21.8680

Chouroulinkov, 1976, Tumour-initiating activities on mouse skin of dihydrodiols derived from benzo[a]pyrene Br, J. Cancer, 34, 523, 10.1038/bjc.1976.207

Denissenko, 1997, Cytosine methylation determines hot spots of DNA damage in the human P53 gene, Proc. Natl. Acad. Sci. USA, 94, 3893, 10.1073/pnas.94.8.3893

Denissenko, 1996, Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53, Science, 274, 430, 10.1126/science.274.5286.430

Eisenstadt, 1982, Carcinogenic epoxides of benzo[a]pyrene and cyclopenta[cd]pyrene induced base substitution via specific transversions, Proc. Natl. Acad. Sci., 79, 1945, 10.1073/pnas.79.6.1945

Feldman, 1980, Formation and excision of covalent deoxyribonucleic acid adducts of benzo[a]pyrene-4,5-epoxide and benzo[a]pyrene diol-epoxide I in human lung cells A549, Biochemistry, 19, 1095, 10.1021/bi00547a008

Grosovsky, 1986, Base substitution, frameshifts, and small deletions constitute ionizing radiation induced point mutations in mammalian cells, Proc. Natl. Acad. Sci., 85, 185, 10.1073/pnas.85.1.185

Kunkel, 1984, Mutational specificity of depurination, Proc. Natl. Acad. Sci., 81, 1494, 10.1073/pnas.81.5.1494

Lowy, 1980, Isolation of transforming DNA. Cloning the hamster aprt gene, Cell, 22, 817, 10.1016/0092-8674(80)90558-9

Machanoff, 1981, Quantitative analysis of cytotoxicity and mutagenicity of benzo[a]pyrene in mammalian cells (CHO/Haprt system), Chem.-Biol. Interact., 34, 1, 10.1016/0009-2797(81)90084-3

Maniatis, 1975, Nucleotide sequence of the rightward operator of phage lambda, Proc. Natl. Acad. Sci., 72, 1184, 10.1073/pnas.72.3.1184

Marsch, 1994, Sequence dependence of benzo[a]pyrene diol expoxide-DNA adduct conformer distribution: a study by laser-induced fluorescence/polyacrylamide gel electrophoresis, Chem. Res. Toxicol., 7, 98, 10.1021/tx00037a015

Mazur, 1988, Sequence specificity of mutations induced by benzo[a]pyrene-7,8-diol-9,10-epoxide at the endogenous aprt gene in CHO cells, Somatic Cell Mol. Biol., 14, 393, 10.1007/BF01534647

M. Mazur, A.J.E. Gordon, C. Bernelot-Moens, B.W. Glickman. Comparison of the mutational specificities exhibited by BPDE in E. coli and CHO cells, in: M.W. Lambert, J. Laval (Eds.), DNA Repair Mechanisms and Their Biological Implications in Mammalian Cells, Plenum Press, New York, 1989.

Moriya, 1996, Fidelity of translesional synthesis past benzo[a]pyrene diol epoxide-2′-deoxyguanosine DNA adducts, marked effects of host cell, sequence context, and chirality, Biochemistry, 35, 16646, 10.1021/bi9608875

Nalbontoglu, 1983, Structure of mutant alleles at the aprt locus of Chinese hamster ovary cells, J. Mol. Biol., 167, 575, 10.1016/S0022-2836(83)80099-0

Newbold, 1976, Exceptional mutagenicity of benzo[a]pyrene diol-epoxide in cultured mammalian cells, Nature, 260, 52, 10.1038/261052a0

F. Oesch, Enzymatic control of metabolically produced epoxides, in: A.R. Boobis, J. Caldwell, F., DeMatteis, C.R. Elcombe (Eds.), Microsomes and Drug Oxidations, Taylor Francis, London, 1985, pp. 178–189.

Pitts, 1980, Atmospheric epoxidation of benzo[a]pyrene by ozone, formation of the metabolite benzo[a]pyrene-4,5-oxide, Science, 210, 1340, 10.1126/science.210.4476.1347

Roilides, 1988, Mutational specificity of benzo[a]pyrene diol-epoxide in monkey cells, Mutat. Res., 198, 199, 10.1016/0027-5107(88)90055-3

Saiki, 1985, Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia, Science, 230, 1350, 10.1126/science.2999980

Schaaper, 1983, Infidelity of DNA synthesis associated with bypass of apurinic sites, Proc. Natl. Acad. Sci., 80, 487, 10.1073/pnas.80.2.487

B.S. Shane, J.G. de Boer, K.R. Tindall, B.W. Glickman Mutational Spectra in Big Blue® transgenic mice treated with benzo[a]pyrene followed by a partial hepatectomy, submitted.

Suh, 1995, Formation and persistence of benzo[a]pyrene-DNA adducts in mouse epidermis in vivo, importance of adduct conformation, Carcinogenesis, 16, 2561, 10.1093/carcin/16.10.2561

Vousden, 1986, Mutations activating human c-Ha-ras proto-oncogene induced by chemical carcinogens and depurination, Proc. Natl. Acad. Sci., 83, 1222, 10.1073/pnas.83.5.1222

Wei, 1993, Dose-dependent differences in the profile of mutations induced by (+)-7R,8S-dihydroxy-9S,10R-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene in Chinese hamster V-79 cells, Cancer. Res., 53, 3294

Wislocki, 1976, High mutagenicity and toxicity of a diol-epoxide derived from benzo[a]pyrene, Biochem. Biophys. Res. Commun., 68, 1006, 10.1016/0006-291X(76)91246-8

Wood, 1976, Mutagenicity and cytotoxicity of benzo[a]pyrene benzo-ring epoxides, Cancer Res., 36, 3358

Wood, 1977, Differences in mutagenicity of the optical enantiomers of diastereomeric benzo[a]pyrene-7,8-diol-9,10-epoxides, Biochem. Biophys. Res. Commun., 17, 1389, 10.1016/S0006-291X(77)80133-2

Yang, 1987, Kinds of mutations formed when a shuttle vector containing adducts of benzo[a]pyrene-7,8-diol-9,10-epoxide replicates in COS7 cells, Mol. Cell Biol., 7, 1267, 10.1128/MCB.7.3.1267

Yang, 1988, Kinds of spectrum of mutations induced by 1-nitrosopyrene adducts during plasmid replication in human cells, Mol. Cell Biol., 8, 3363, 10.1128/MCB.8.8.3364

de Boer, 1992, Mutations recovered in the Chinese hamster aprt gene after exposure to carboplatin: a comparison with cisplatin, Carcinogenesis, 13, 15, 10.1093/carcin/13.1.15