A combined oral contraceptive containing drospirenone changes neither endothelial function nor hemodynamic parameters in healthy young women: a prospective clinical trial

Stadel, 1981, Oral contraceptives and cardiovascular disease (second of two parts), N Engl J Med, 305, 672, 10.1056/NEJM198109173051205 Burkman, 2001, Current perspectives on oral contraceptive use, Am J Obstet Gynecol, 185, S4, 10.1067/mob.2001.117416 Mishell, 1992, Oral contraception: past, present, and future perspectives, Int J Fertil, 37, 7 Kemmeren, 2001, Third generation oral contraceptives and risk of venous thrombosis: meta-analysis, BMJ, 323, 131, 10.1136/bmj.323.7305.131 Baillargeon, 2005, Association between the current use of low-dose oral contraceptives and cardiovascular arterial disease: a meta-analysis, J Clin Endocrinol Metab, 90, 3863, 10.1210/jc.2004-1958 Chasan-Taber, 1996, Prospective study of oral contraceptives and hypertension among women in the United States, Circulation, 94, 483, 10.1161/01.CIR.94.3.483 Oelkers, 1974, Effects of progesterone and four synthetic progestogens on sodium balance and the renin–aldosterone system in man, J Clin Endocrinol Metab, 39, 882, 10.1210/jcem-39-5-882 Oelkers, 1996, Effects of estrogens and progestogens on the renin–aldosterone system and blood pressure, Steroids, 61, 166, 10.1016/0039-128X(96)00007-4 Buchner, 2003, Oral contraceptives and endothelial function: harm or benefit?, J Hypertens, 21, 2227, 10.1097/00004872-200312000-00005 John, 2000, Effects of oral contraceptives on vascular endothelium in premenopausal women, Am J Obstet Gynecol, 183, 28, 10.1016/S0002-9378(00)37848-6 Virdis, 2003, Effect of oral contraceptives on endothelial function in the peripheral microcirculation of healthy women, J Hypertens, 21, 2275, 10.1097/00004872-200312000-00015 Torgrimson, 2007, Endothelial function across an oral contraceptive cycle in women using levonorgestrel and ethinyl estradiol, Am J Physiol Heart Circ Physiol, 288, H103 Lizarelli, 2009, Both a combined oral contraceptive and depot medroxyprogesterone acetate impair endothelial function in young women, Contraception, 79, 35, 10.1016/j.contraception.2008.07.024 Meendering, 2009, Ethinyl estradiol-to-desogestrel ratio impacts endothelial function in young women, Contraception, 79, 41, 10.1016/j.contraception.2008.07.025 Meendering, 2010, A combined oral contraceptive containing 30 μg ethinyl estradiol and 3.0 mg drospirenone does not impair endothelium-dependent vasodilation, Contraception, 82, 366, 10.1016/j.contraception.2010.03.009 Oelkers, 1991, Dihydrospirorenone, a new progestogen with antimineralocorticoid activity: effects on ovulation, electrolyte excretion and the renin–aldosterone system in normal women, J Clin Endocrinol Metab, 73, 837, 10.1210/jcem-73-4-837 Oelkers, 1995, Effects of a new oral contraceptive containing an antimineralocorticoid progestogen, drospirenone, on the renin–aldosterone system, body weight, blood pressure, glucose tolerance, and lipid metabolism, J Clin Endocrinol Metab, 80, 1816, 10.1210/jc.80.6.1816 Oelkers, 2002, Antimineralocorticoid activity of a novel oral contraceptive containing drospirenone, a unique progestogen resembling natural progesterone, Eur J Contracept Reprod Health Care, 7, 19 Oelkers, 2000, Effect of an oral contraceptive containing drospirenone on the renin–angiotensin–aldosterone system in healthy female volunteers, Gynecol Endocrinol, 14, 476, 10.3109/09513590009167683 Preston, 2002, Additive effect of drospirenone/17-beta estradiol in hypertensive postmenopausal women receiving enalapril, Am J Hypertens, 15, 816, 10.1016/S0895-7061(02)02980-1 Preston, 2005, Effects of drospirenone/17-beta estradiol on blood pressure and potassium balance in hypertensive postmenopausal women, Am J Hypertens, 18, 797, 10.1016/j.amjhyper.2004.12.003 White, 2005, Antihypertensive effects of drospirenone with 17-beta-estradiol, a novel hormone treatment in post-menopausal women with stage 1 hypertension, Circulation, 112, 1979, 10.1161/CIRCULATIONAHA.104.501502 White, 2006, Effects of a new hormone therapy, drospirenone and 17-β-estradiol, in post-menopausal women with hypertension, Hypertension, 48, 246, 10.1161/01.HYP.0000232179.60442.84 Sica, 2006, Drospirenone: an antihypertensive in waiting, Hypertension, 48, 205, 10.1161/01.HYP.0000232180.72752.f8 Simoncini, 2007, Drospirenone increases endothelial nitric oxide synthesis via a combined action on progesterone and mineralocorticoid receptors, Hum Reprod, 22, 2325, 10.1093/humrep/dem109 World Health Organization, 2009 Pickering, 2005, Hypertension, 45, 142, 10.1161/01.HYP.0000150859.47929.8e O'Brien, 1990, Inaccuracy of the random zero sphygmomanometer, Lancet, 336, 1465, 10.1016/0140-6736(90)93177-Q Bos, 1996, Reconstruction of brachial artery pressure from noninvasive finger pressure measurement, Circulation, 94, 1870, 10.1161/01.CIR.94.8.1870 Imholz, 1998, Fifteen years experience with finger arterial pressure monitoring: assessment of the technology, Cardiovasc Res, 38, 605, 10.1016/S0008-6363(98)00067-4 AAMI, 1993 Finometer™ user's guide. Anhem (The Netherlands): FMS, Finapres Medical System. Copyright 2003 FMS. Corretti, 2002, International Brachial Artery Reactivity Task Force. Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: a report of the International Brachial Artery Reactivity Task Force, J Am Coll Cardiol, 39, 257, 10.1016/S0735-1097(01)01746-6 Diggle, 2002 Bussab, 2002 McCullagh, 1989 Gibbons, 2003 Hardin, 2003 Fuhrmann, 1996, The novel progestin drospirenone and its natural counterpart progesterone: biochemical profile and anti-androgenic potential, Contraception, 54, 243, 10.1016/S0010-7824(96)00195-3 Suthipongse, 2004, An open-label randomized comparative study of oral contraceptives between medications containing 3 mg drospirenone/30 μg ethinylestradiol and 150 μg levonogestrel/30 μg ethinylestradiol, Thai Women Contracept, 69, 23, 10.1016/j.contraception.2003.08.014 Hannaford, 2000, Cardiovascular events associated with different combined oral contraceptives: a review of current data, Drug Saf, 22, 361, 10.2165/00002018-200022050-00004