A case with life-threatening interstitial pneumonia associated with bucillamine treatment

Oxford University Press (OUP) - Tập 18 - Trang 522-525 - 2008
Yuiko Ogiwara1, Hideaki Mochizuki1, Takehiko Morioka2, Takahiko Sugihara3, Fumihiko Makino1, Hideki Takahashi1
1Division of Respiratory Medicine, Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan
2Division of Hematology, Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan
3Division of Medicine and Rheumatology, Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan

Tóm tắt

We report a case of bucillamine-induced interstitial pneumonia accompanied by severe hypoxemia in an 83-year-old woman who had rheumatoid arthritis. Respiratory failure worsened even after withdrawal of bucillamine and administration of high-dose corticosteroids, and mechanical ventilation was required. A review of 15 cases with bucillamine-induced pulmonary injury suggests that advanced age may be associated with the development of severe interstitial pneumonia. Bucillamine can cause corticosteroid-resistant and life-threatening lung injury, especially in the elderly.

Tài liệu tham khảo

Sekiguchi N, Kameda H, Amano K, Takeuchi T. Efficacy and safety of bucillamine, a D-penicillamine analogue, in patients with rheumatoid arthritis. Mod Rheumatol. 2006;16:85–91. Hara A, Sakamoto O, Matsumoto M, et al. A case of bucillamine-induced interstitial pneumonia. Nihon Kyobu Shikkan Gakkai Zasshi. 1992;30:1743–8 (in Japanese). Tanaka H, Nakahara K, Goto K. A case of bucillamine-induced pneumonitis. Nihon Kyobu Shikkan Gakkai Zasshi. 1992;30:695–701 (in Japanese). Inokuma S, Sakata M, Yoshida A, Shiratori K, Kiyosawa H. Bucillamine induced pulmonary injury occurs with immunoglobulin decrease. J Rheumatol. 1996;23:1282–5. Fukino K, Shiota T, Nakaya Y, et al. A case of drug-induced interstitial pneumonitis in rheumatoid arthritis treated with bucillamone. Bronchology. 1997;19:232–6 (in Japanese). Lee YH, Kim YR, Ji JD, et al. A case of BOOP developed during bucillamine treatment for rheumatoid. Korean J Intern Med. 2001;16:36–9. Matsushima H, Takayanagi N, Sakamoto T, et al. A case of drug-induced interstitial pneumonitis in rheumatoid arthritis treated with bucillamine. Nihon Kokyuki Gakkai Zasshi. 2001;39(1):55–9 (in Japanese). Miwa Y, Kaga S, Hanaoka R, et al. A case of rheumatoid arthritis complicated with a pneumonitis during concomitant treatment with methotrexate and bucillamine. Ryumachi. 2002;42:70–5 (in Japanese). Kishimoto N, Fujii K. A case of pulmonary infiltration with eosinophilia (PIE) syndrome induced by bucillamine treatment of rheumatoid arthritis. Nihon Kokyuki Gakkai Zasshi. 2002;40:321–5 (in Japanese). Tanimura K, Shimizu M, Matsuhashi M, Shinohara M, Sagawa A. A case of interstitial pneumonia caused by bucillamine: a study using serological markers. Mod Rheumatol. 2006;16:39–43. Nanke Y, Yamada T, Kamatani N. Asymptomatic interstitial pneumonitis induced by bucillamine in a patient with rheumatoid arthritis. Mod Rheumatol. 2005;15:381–2. Kajiya T, Kuroda A, Hokonohara D, Tei C. Radiographic appearance of bronchiolitis obliterans organizing pneumonia (BOOP) developing during Bucillamine treatment for rheumatoid arthritis. Am J Med Sci. 2006;332:39–42. Saito Y, Nei T, Abe S, et al. A case of bucillamine-induced interstitial pneumonia with positive lymphocyte stimulation test for bucillamine using bronchoalveolar lavage lymphocytes. Intern Med. 2007;46:1739–43. Arnett FC, Edworthy SM, Bloch DA, et al. The American rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 1988;31:315–24. Brown KK. Rheumatoid lung disease. Proc Am Thorac Soc. 2007;4:443–8. Negishi M, Kaga S, Kasama T, et al. Lung injury associated with bucillamine therapy. Ryumachi. 1992;32:135–9 (in Japanese). Kurashima K, Nakao S, Fujimura M, Matsuda T. Bucillamine-induced hypersensitivity pneumonitis. Chest. 1992;101:1479–80. Battaglia S, Sandrini MC, Catalano F, et al. Effects of aging on sensation of dyspnea and health-related quality of life in elderly asthmatics. Aging Clin Exp Res. 2005;17:287–92.