A case of unexpected regeneration of small intestinal mucosal necrosis
Tóm tắt
If full-thickness mucosa, including the mucosal crypt, has been almost denuded, mucosa cannot regenerate as has been shown by animal models. The authors experienced an unusual mucosal regeneration exceed denuded bowel that occur in midgut volvulus of duration 2 days in a 6-day-old infant. Santulli’s jejunostomy was performed using seriously denuded small bowel to prevent short bowel syndrome, despite the risks of leakage or stricture. Subsequently, stomal mucosa was fully regenerated when grossly identified 19 days after the second operation without any surgical complications.
Tài liệu tham khảo
Stewart DR, Colodny AL, Daggett WC (1976) Malrotation of the bowel in infants and children: a 15 year review. Surgery 79:716–720
Park PO, Haglund U (1992) Regeneration of small bowel mucosa after intestinal ischemia. Crit Care Med 20:135–139
Critchlow J, Magee D, Ito S, Takeuchi K, Silen W (1985) Requirements for restitution of the surface epithelium of frog stomach after mucosal injury. Gastroenterology 88:237–249
Argenzio RA, Henrikson CK, Liacos JA (1988) Restitution of barrier and transport function of porcine colon after acute mucosal injury. Am J Physiol 255:G62–G71
Podolsky DK (1993) Regulation of intestinal epithelial proliferation: a few answers, many questions. Am J Physiol 264:G179–G186
Taylor RG, Verity K, Fuller PJ (1990) Ileal glucagon gene expression: ontogeny and response to massive small bowel resection. Gastroenterology 99:724–729
Touloukian RJ, Smith GJ (1983) Normal intestinal length in preterm infants. J Pediatr Surg 18:720–723
Barker N, van Es JH, Kuipers J, Kujala P, van den Born M, Cozijnsen M, Haegebarth A, Korving J, Begthel H, Peters PJ, Clevers H (2007) Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 449:1003–1007
May R, Riehl TE, Hunt C, Sureban SM, Anant S, Houchen CW (2008) Identification of a novel putative gastrointestinal stem cell and adenoma stem cell marker, doublecortin and CaM kinase-like-1, following radiation injury and in adenomatous polyposis coli/multiple intestinal neoplasia mice. Stem Cells 26:630–637