A Novel PD-L1-targeting Antagonistic DNA Aptamer With Antitumor Effects
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Sharma, 2015, Immune checkpoint targeting in cancer therapy: toward combination strategies with curative potential, Cell, 161, 205, 10.1016/j.cell.2015.03.030
Domling, 2014, Programmed death-1: therapeutic success after more than 100 years of cancer immunotherapy, Angew Chem Int Ed, 53, 2286, 10.1002/anie.201307906
Smyth, 2016, Combination cancer immunotherapies tailored to the tumour microenvironment, Nat Rev Clin Oncol, 13, 143, 10.1038/nrclinonc.2015.209
Okazaki, 2013, A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application, Nat Immunol, 14, 1212, 10.1038/ni.2762
Herbst, 2014, Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients, Nature, 515, 563, 10.1038/nature14011
Okazaki, 2007, PD-1 and PD-1 ligands: from discovery to clinical application, Int Immunol, 19, 813, 10.1093/intimm/dxm057
Callahan, 2013, At the bedside: CTLA-4- and PD-1-blocking antibodies in cancer immunotherapy, J Leukoc Biol, 94, 41, 10.1189/jlb.1212631
Intlekofer, 2013, At the bench: preclinical rationale for CTLA-4 and PD-1 blockade as cancer immunotherapy, J Leukoc Biol, 94, 25, 10.1189/jlb.1212621
Samaranayake, 2009, Challenges in monoclonal antibody-based therapies, Ann Med, 41, 322, 10.1080/07853890802698842
Prodeus, 2015, Targeting the PD-1/PD-L1 immune evasion axis with DNA aptamers as a novel therapeutic strategy for the treatment of disseminated cancers, Mol Ther Nucleic Acids, 4, e237, 10.1038/mtna.2015.11
Lao, 2015, Aptamer nanomedicine for cancer therapeutics: barriers and potential for translation, ACS Nano, 9, 2235, 10.1021/nn507494p
Sun, 2014, Oligonucleotide aptamers: new tools for targeted cancer therapy, Mol Ther Nucleic Acids, 3, e182, 10.1038/mtna.2014.32
Gilboa, 2013, Use of oligonucleotide aptamer ligands to modulate the function of immune receptors, Clin Cancer Res, 19, 1054, 10.1158/1078-0432.CCR-12-2067
Xiang, 2015, Nucleic acid aptamer-guided cancer therapeutics and diagnostics: the next generation of cancer medicine, Theranostics, 5, 23, 10.7150/thno.10202
Ng, 2006, Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease, Nat Rev Drug Discov, 5, 123, 10.1038/nrd1955
Kato, 2016, Structural basis for specific inhibition of Autotaxin by a DNA aptamer, Nat Struct Mol Biol, 23, 395, 10.1038/nsmb.3200
Chen, 2011, IL-17RA aptamer-mediated repression of IL-6 inhibits synovium inflammation in a murine model of osteoarthritis, Osteoarthritis Cartilage, 19, 711, 10.1016/j.joca.2011.01.018
Wheeler, 2011, Inhibition of HIV transmission in human cervicovaginal explants and humanized mice using CD4 aptamer-siRNA chimeras, J Clin Invest, 121, 2401, 10.1172/JCI45876
Ozer, 2014, New technologies provide quantum changes in the scale, speed, and success of SELEX methods and aptamer characterization, Mol Ther Nucleic Acids, 3, e183, 10.1038/mtna.2014.34
Blind, 2015, Aptamer selection technology and recent advances, Mol Ther Nucleic Acids, 4, e223, 10.1038/mtna.2014.74
Alam, 2015, FASTAptamer: a bioinformatic toolkit for high-throughput sequence analysis of combinatorial selections, Mol Ther Nucleic Acids, 4, e230, 10.1038/mtna.2015.4
Li, 2015, The EMBL-EBI bioinformatics web and programmatic tools framework, Nucleic Acids Res, 43, W580, 10.1093/nar/gkv279
Lin, 2008, The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors, Proc Natl Acad Sci USA, 105, 3011, 10.1073/pnas.0712278105
Singh, 2007, Chemokines in tumor angiogenesis and metastasis, Cancer Metastasis Rev, 26, 453, 10.1007/s10555-007-9068-9
Zuker, 2003, Mfold web server for nucleic acid folding and hybridization prediction, Nucleic Acids Res, 31, 3406, 10.1093/nar/gkg595
Popenda, 2012, Automated 3D structure composition for large RNAs, Nucleic Acids Res, 40, e112, 10.1093/nar/gks339
Duhovny, 2002, Efficient unbound docking of rigid molecules, Lect Notes Comput Sc, 2452, 185, 10.1007/3-540-45784-4_14
Schneidman-Duhovny, 2005, PatchDock and SymmDock: servers for rigid and symmetric docking, Nucleic Acids Res, 33, W363, 10.1093/nar/gki481
Schindelin, 2015, The ImageJ ecosystem: an open platform for biomedical image analysis, Mol Reprod Dev, 82, 518, 10.1002/mrd.22489
Schindelin, 2012, Fiji: an open-source platform for biological-image analysis, Nat Methods, 9, 676, 10.1038/nmeth.2019
Pachynski, 2015, Evaluation of tumor-infiltrating leukocyte subsets in a subcutaneous tumor model, J Vis Exp, 98, e52657