A Novel Mechanism of EML4-ALK Rearrangement Mediated by Chromothripsis in a Patient-Derived Cell Line

Journal of Thoracic Oncology - Tập 9 - Trang 1638-1646 - 2014
Tatsushi Kodama1, Noriko Motoi2,3, Hironori Ninomiya2,3, Hiroshi Sakamoto1, Kunio Kitada1, Toshiyuki Tsukaguchi1, Yasuko Satoh1, Kimie Nomura2, Hiroko Nagano2, Nobuya Ishii1, Yasuhito Terui4, Kiyohiko Hatake4, Yuichi Ishikawa2,3
1Research Division, Chugai Pharmaceutical Co., Ltd., Kamakura, Japan
2Division of Pathology, The Cancer Institute, Tokyo, Japan
3Department of Pathology, The Cancer Institute Hospital, Tokyo, Japan
4Division of Clinical Chemotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo, Japan

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