A Gradient of 2-Arachidonoylglycerol Regulates Mouse Epididymal Sperm Cell Start-Up1

Biology of Reproduction - Tập 82 Số 2 - Trang 451-458 - 2010
Gilda Cobellis1,2, Giulia Ricci3,1, Giovanna Cacciola1, Pierangelo Orlando4, Stefania Petrosino5, Maria Grazia Cascio5, Tiziana Bisogno5, Luciano De Petrocellis6, Teresa Chioccarelli7, Lucia Altucci1,2, Silvia Fasano1,2, Rosaria Meccariello8, Riccardo Pierantoni1,2, Catherine Ledent9, Vincenzo Di Marzo5,3
1Dipartimento di Medicina Sperimentale, Sez. “F. Bottazzi,” Seconda Università degli Studi di Napoli, Napoli, Italy
2Istituto Nazionale Biostrutture e Biosistemi (INBB), Consorzio Interuniversitario, Sezione di Napoli, Napoli, Italy
3Dipartimento di Medicina Sperimentale, Laboratorio di Istologia ed Embriologia, Seconda Università degli Studi di Napoli, Napoli, Italy
4Institutes of Protein Biochemistry, Endocannabinoid Research Group, Consiglio Nazionale delle Ricerche, Pozzuoli, Italy
5Biomolecular Chemistry, Endocannabinoid Research Group, Consiglio Nazionale delle Ricerche, Pozzuoli, Italy
6Cybernetics, Endocannabinoid Research Group, Consiglio Nazionale delle Ricerche, Pozzuoli, Italy
7Dipartimento di Patologia Generale, Seconda Università degli Studi di Napoli, Napoli, Italy
8Dipartimento di Studi delle Istituzioni e dei Sistemi Territoriali, Università degli Studi di Napoli Parthenope, Napoli, Italy
9IRIBHM, Université Libre de Bruxelles, Brussels, Belgium

Tóm tắt

Từ khóa


Tài liệu tham khảo

1992, Isolation and structure of a brain constituent that binds to the cannabinoid receptor., Science, 258, 1946, 10.1126/science.1470919

2002, Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance., Prost Leuk Essent Fatty Acids, 66, 101

2002, N-Acylethanolamines in human reproductive fluids., Chem Phys Lipids, 121, 211, 10.1016/S0009-3084(02)00158-5

2002, Cannabinoid receptors and their ligands., Prost Leuk Essent Fatty Acids, 66, 101, 10.1054/plef.2001.0341

1990, Structure of a cannabinoid receptor and functional expression of the cloned cDNA., Nature, 346, 561, 10.1038/346561a0

1993, Molecular characterization of a peripheral receptor for cannabinoids., Nature, 365, 61, 10.1038/365061a0

2002, International Union of Pharmacology. XXVII. Classification of cannabinoid receptors., Pharmacol Rev, 54, 161, 10.1124/pr.54.2.161

1995, Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors., Biochem Pharmacol, 50, 83, 10.1016/0006-2952(95)00109-D

1996, Enzymatic synthesis of anandamide, an endogenous cannabinoid receptor ligand, through N-acylphosphatidylethanolamine pathway in testis: involvement of Ca(2+)-dependent transacylase and phosphodiesterase activities., Biochem Biophys Res Commun, 218, 113, 10.1006/bbrc.1996.0020

2007, Endocannabinoids and related compounds: walking back and forth between plant natural products and animal physiology., Chem Biol, 14, 741, 10.1016/j.chembiol.2007.05.014

2005, Anandamide acts as an intracellular messenger amplifying Ca2+ influx via TRPV1 channels., EMBO J, 24, 3026, 10.1038/sj.emboj.7600784

2004, Molecular characterization of a phospholipase D generating anandamide and its congeners., J Biol Chem, 279, 5298, 10.1074/jbc.M306642200

2003, Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain., J Cell Biol, 163, 463, 10.1083/jcb.200305129

1994, Formation and inactivation of endogenous cannabinoid anandamide in central neurons., Nature, 372, 686, 10.1038/372686a0

1996, Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides., Nature, 384, 83, 10.1038/384083a0

2002, Brain monoglyceride lipase participating in endocannabinoid inactivation., Proc Natl Acad Sci, 99, 10819, 10.1073/pnas.152334899

2005, Characterization of the endocannabinoid system in boar spermatozoa and implications for sperm capacitation and acrosome reaction., J Cell Sci, 118, 4393, 10.1242/jcs.02536

2002, Evidence that anandamide-signaling regulates human sperm functions required for fertilization., Mol Reprod Develop, 63, 376, 10.1002/mrd.90021

2005, Human sperm express cannabinoid receptor CNR1, the activation of which inhibits motility, acrosome reaction, and mitochondrial function., J Clin Endocrinol Metab, 90, 984, 10.1210/jc.2004-1287

2006, Endocannabinoid system in frog and rodent testis: type-1 cannabinoid receptor and fatty acid amide hydrolase activity in male germ cells., Biol Reprod, 75, 82, 10.1095/biolreprod.106.051730

1994, Mammalian fertilization., The Physiology of Reproduction, 2nd ed, 189

1994, Development of sperm motility patterns in the murine epididymis., Int J Androl, 17, 271, 10.1111/j.1365-2605.1994.tb01253.x

1980, Relations between the fertilization ability, motility and metabolism of epididymal spermatozoa., Reprod Nutr Dev, 20, 1085, 10.1051/rnd:19800617

1999, Unresponsiveness to cannabinoids and reduced addictive effects of opiates in Cnr1 knockout mice., Science, 283, 401, 10.1126/science.283.5400.401

1990, The influence of chamber characteristics on the reliability of sperm concentration and movement measurements obtained by manual and videomicrographic analysis., Fertil Steril, 53, 882, 10.1016/S0015-0282(16)53526-2

2002, Functional role of hepatocyte growth factor receptor during sperm maturation., J Androl, 23, 911, 10.1002/j.1939-4640.2002.tb02349.x

1997, Cannabinoids inhibit N- and P/Q-type calcium channels in cultured rat hippocampal neurons., J Neurophysiol, 78, 43, 10.1152/jn.1997.78.1.43

1999, Internalization and recycling of the CB1 cannabinoid receptor., J Neurochem, 73, 493, 10.1046/j.1471-4159.1999.0730493.x

2000, Cannabinoids inhibit hippocampal GABAergic transmission and network oscillations., Eur J Neurosci, 12, 3239, 10.1046/j.1460-9568.2000.00217.x

2002, CB1 cannabinoid receptors in amphibian spinal cord: relationships with some nociception markers., J Chem Neuroanat, 24, 153, 10.1016/S0891-0618(02)00040-6

2001, Leptin-regulated endocannabinoids are involved in maintaining food intake., Nature, 410, 822, 10.1038/35071088

2001, The activity of anandamide at vanilloid VR1 receptors requires facilitated transport across the cell membrane and is limited by intracellular metabolism., J Biol Chem, 276, 12856, 10.1074/jbc.M008555200

2007, Endocannabinoid control of sperm motility: the role of epididymis., Gen Comp Endocrinol, 153, 320, 10.1016/j.ygcen.2007.02.003

2008, TRPV1 channels mediate long-term depression at synapses on hippocampal interneurons., Neuron, 57, 746, 10.1016/j.neuron.2007.12.027

2009, The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis., Proc Natl Acad Sci U S A, 106, 1131

2005, Identification of post-translational modifications that occur during sperm maturation using difference in two-dimensional gel electrophoresis., Proteomics, 5, 1003, 10.1002/pmic.200401100

2007, Cyclin-dependent kinase 5 modulates nociceptive signaling through direct phosphorylation of transient receptor potential vanilloid 1., Proc Natl Acad Sci U S A, 104, 660, 10.1073/pnas.0609916104

2006, Oleoylethanolamide protects human sperm cells from oxidation stress: studies on cases of idiopathic infertilità., Biol Reprod, 74, 659, 10.1095/biolreprod.105.046060

2009, Genetic loss of faah compromises male fertility in mice., Biol Reprod, 80, 235, 10.1095/biolreprod.108.072736

1997, Functional role of high-affinity anandamide transport, as revealed by selective inhibition., Science, 277, 1094, 10.1126/science.277.5329.1094

2003, Novel selective and metabolically stable inhibitors of anandamide cellular uptake., Biochem Pharmacol, 65, 1473, 10.1016/S0006-2952(03)00109-6

2004, Aberrant cannabinoid signaling impairs oviductal transport of embryos., Nat Med, 10, 1074, 10.1038/nm1104

2005, Effects of cannabinoids on hypothalamic and reproductive function., Handb Exp Pharmacol, 168, 555, 10.1007/3-540-26573-2_18

2006, Jekyll and Hyde: two faces of cannabinoid signaling in male and female fertility., Endocr Rev, 27, 427, 10.1210/er.2006-0006