A Case of Acute Pneumonitis Induced by Injection of Silicone for Colpoplasty

Respiration - Tập 70 Số 1 - Trang 104-106 - 2003
Cheol Hyeon Kim1, Doo Hyun Chung2, Chul‐Gyu Yoo1, Choon‐Taek Lee1, Sung Koo Han1, Young‐Soo Shim1, Young Whan Kim1
1Department of Internal Medicine, Seoul National University College of Medicine and Lung Institute, Medical Research Center, Seoul National University, and
2Department of Pathology, Seoul National University College of Medicine, Seoul, Korea

Tóm tắt

Silicone fluid (polymethylsiloxane) is a liquid polymer that had been widely used in breast augmentation and other cosmetic procedures. However, many adverse reactions after silicone injections into human beings have been reported including adverse pulmonary sequelae. We report a case of a 46-year-old woman who suffered from acute pneumonitis that was induced by illicit injection of silicone into the vaginal wall for colpoplasty. The pulmonary involvement was documented by transbronchial lung biopsy and bronchoalveolar lavage where examination with the electron microscope disclosed the presence of large quantities of pleomorphic cytoplasmic inclusions in alveolar macrophages. Clinicians should be aware of this unusual complication of injection of silicone.

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