A 3D co-culture intestinal organoid system for exploring glucose metabolism

Current Research in Food Science - Tập 6 - Trang 100402 - 2023
Jianping Nie1, Wei Liao1, Zijie Zhang1, Minjiao Zhang1, Yuxi Wen2, Esra Capanoglu3, Md Moklesur Rahman Sarker4, Ruiyu Zhu5, Chao Zhao2,1,6
1College of Food Science, Fujian Agriculture and Forestry University, Fuzhou, China
2College of Marine Sciences, Fujian Agriculture and Forestry University, Fuzhou, China
3Department of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Istanbul Technical University, Maslak, 34469 Istanbul, Turkey
4Department of Pharmacy, State University of Bangladesh, Dhaka, Bangladesh
5School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, China
6Key Laboratory of Marine Biotechnology of Fujian Province, Institute of Oceanology, Fujian Agriculture and Forestry University, Fuzhou, China

Tài liệu tham khảo

Agunloye, 2022, Blood glucose lowering and effect of oyster (Pleurotus ostreatus)- and shiitake (Lentinus subnudus)-supplemented diet on key enzymes linked diabetes and hypertension in streptozotocin-induced diabetic in rats, Food Frontiers, 3, 161, 10.1002/fft2.111 Artegiani, 2018, Use and application of 3d-organoid technology, Hum. Mol. Genet., 27, R99, 10.1093/hmg/ddy187 Balboa, 2018, Insulin mutations impair beta-cell development in a patient-derived iPSC model of neonatal diabetes, Elife, 7, 10.7554/eLife.38519 Bar-Ephraim, 2020, Organoids in immunological research, Nat. Rev. Immunol., 20, 279, 10.1038/s41577-019-0248-y Bartfeld, 2015, In vitro expansion of human gastric epithelial stem cells and their responses to bacterial infection, Gastroenterology, 148, 126, 10.1053/j.gastro.2014.09.042 Bewick, 2021, The way to the heart of diabetes is through your gut, Biochemist, 43, 10, 10.1042/bio_2021_111 Bielka, 2022, The role of the gut microbiota in the pathogenesis of diabetes, Int. J. Mol. Sci., 23, 480, 10.3390/ijms23010480 Biton, 2018, T helper cell cytokines modulate intestinal stem cell renewal and differentiation, Cell, 175, 1307, 10.1016/j.cell.2018.10.008 Bouchi, 2014, FOXO1 inhibition yields functional insulin-producing cells in human gut organoid cultures, Nat. Commun., 5, 4242, 10.1038/ncomms5242 Brafman, 2013, Constructing stem cell microenvironments using bioengineering approaches, Physiol. Genom., 45, 1123, 10.1152/physiolgenomics.00099.2013 Broda, 2018, Generation of human antral and fundic gastric organoids from pluripotent stem cells, Nat. Protoc., 14, 28, 10.1038/s41596-018-0080-z Brooks, 2016, Fermentable carbohydrate stimulates FFAR2-dependent colonic PYY cell expansion to increase satiety, Mol. Metabol., 6, 48, 10.1016/j.molmet.2016.10.011 Burkitt, 2017, Helicobacter pylori-induced gastric pathology: insights from in vivo and ex vivo models, Dis. Model. Mech., 10, 89, 10.1242/dmm.027649 Capeling, 2019, Nonadhesive alginate hydrogels support growth of pluripotent stem cell-derived intestinal organoids, Stem Cell Rep., 12, 381, 10.1016/j.stemcr.2018.12.001 Chen, 2014, De novo formation of insulin-producing "neo-β cell islets" from intestinal crypts, Cell Rep., 6, 1046, 10.1016/j.celrep.2014.02.013 Chusilp, 2020, Intestinal organoids in infants and children, Pediatr. Surg. Int., 36, 1, 10.1007/s00383-019-04581-3 Clevers, 2016, Modeling development and disease with organoids, Cell, 165, 1586, 10.1016/j.cell.2016.05.082 Costa, 2016, 3D tumor spheroids: an overview on the tools and techniques used for their analysis, Biotechnol. Adv., 34, 1427, 10.1016/j.biotechadv.2016.11.002 Cukierman, 2001, Taking cell-matrix adhesions to the third dimension, Science, 294, 1708, 10.1126/science.1064829 Cunningham, 2021, Intestinal microbiota and their metabolic contribution to type 2 diabetes and obesity, J. Diabetes Metab. Disord., 20, 1855, 10.1007/s40200-021-00858-4 Dekkers, 2013, A functional CFTR assay using primary cystic fibrosis intestinal organoids, Nat. Med., 19, 939, 10.1038/nm.3201 Drost, 2017, Translational applications of adult stem cell-derived organoids, Development, 144, 968, 10.1242/dev.140566 Dunne, 2014, Human decellularized adipose tissue scaffold as a model for breast cancer cell growth and drug treatments, Biomaterials, 35, 4940, 10.1016/j.biomaterials.2014.03.003 Dutta, 2017, Disease modeling in stem cell-derived 3D organoid systems, Trends Mol. Med., 23, 393, 10.1016/j.molmed.2017.02.007 Dye, 2015, In vitro generation of human pluripotent stem cell derived lung organoids, Elife, 4, 10.7554/eLife.05098 Farin, 2016, Visualization of a short-range Wnt gradient in the intestinal stem-cell niche, Nature, 530, 340, 10.1038/nature16937 Fatehullah, 2016, Organoids as an in vitro model of human development and disease, Nat. Cell Biol., 18, 246, 10.1038/ncb3312 Filippello, 2021, High glucose exposure impairs L-cell differentiation in intestinal organoids: molecular mechanisms and clinical implications, Int. J. Mol. Sci., 22, 6660, 10.3390/ijms22136660 Filippello, 2022, Molecular effects of chronic exposure to palmitate in intestinal organoids: a new model to study obesity and diabetes, Int. J. Mol. Sci., 23, 7751, 10.3390/ijms23147751 Fligor, 2020, Differentiation of retinal organoids from human pluripotent stem cells, Methods Cell Biol., 159, 279, 10.1016/bs.mcb.2020.02.005 Fujii, 2016, A colorectal tumor organoid library demonstrates progressive loss of niche factor requirements during tumorigenesis, Cell Stem Cell, 18, 827, 10.1016/j.stem.2016.04.003 Gattazzo, 2014, Extracellular matrix: a dynamic microenvironment for stem cell niche, Biochim. Biophys. Acta, 1840, 2506, 10.1016/j.bbagen.2014.01.010 Gilbert, 2020, GLP-1 analogs and DPP-4 inhibitors in type 2 diabetes therapy: review of head-to-head clinical trials, Front. Endocrinol., 11, 178, 10.3389/fendo.2020.00178 Giobbe, 2019, Extracellular matrix hydrogel derived from decellularized tissues enables endodermal organoid culture, Nat. Commun., 10, 5658, 10.1038/s41467-019-13605-4 Goldspink, 2020, Labeling and characterization of human GLP-1-secreting L-cells in primary ileal organoid culture, Cell Rep., 31, 10.1016/j.celrep.2020.107833 Gómez, 2021, Organoids and their use in modeling gut epithelial cell lineage differentiation and barrier properties during intestinal diseases, Front. Cell Dev. Biol., 9, 10.3389/fcell.2021.732137 Haisler, 2013, Three-dimensional cell culturing by magnetic levitation, Nat. Protoc., 8, 1940, 10.1038/nprot.2013.125 Holmes, 2011, A human NK cell activation/inhibition threshold allows small changes in the target cell surface phenotype to dramatically alter susceptibility to NK cells, J. Immunol., 186, 1538, 10.4049/jimmunol.1000951 Homan, 2019, Flow-enhanced vascularization and maturation of kidney organoids in vitro, Nat. Methods, 16, 255, 10.1038/s41592-019-0325-y Home, 2014, Insulin therapy in people with type 2 diabetes: opportunities and challenges?, Diabetes Care, 37, 1499, 10.2337/dc13-2743 Huang, 2021, Recent advance of in vitro models in natural phytochemicals absorption and metabolism, eFood, 2, 307, 10.53365/efood.k/146945 Idris, 2021, Intestinal multicellular organoids to study colorectal cancer, Biochim. Biophys. Acta, Rev. Cancer, 1876, 10.1016/j.bbcan.2021.188586 Imamura, 2015, Comparison of 2D- and 3D-culture models as drug-testing platforms in breast cancer, Oncol. Rep., 33, 1837, 10.3892/or.2015.3767 Jensen, 2020, Is it time to start transitioning from 2d to 3d cell culture?, Front. Mol. Biosci., 7, 33, 10.3389/fmolb.2020.00033 Kazeem, 2021, Functional foods with dipeptidyl peptidase-4 inhibitory potential and management of type 2 diabetes: a review, Food Frontiers, 2, 153, 10.1002/fft2.71 Kim, 2005, Mitogenic influence of human R-spondin1 on the intestinal epithelium, Science, 309, 1256, 10.1126/science.1112521 Kim, 2022, Intestinal extracellular matrix hydrogels to generate intestinal organoids for translational applications, J. Ind. Eng. Chem., 25, 155, 10.1016/j.jiec.2021.11.044 Kleinman, 2005, Matrigel: basement membrane matrix with biological activity, Semin. Cancer Biol., 15, 378, 10.1016/j.semcancer.2005.05.004 Koch, 2020, Laparoscopic vertical sleeve gastrectomy as a treatment option for adults with diabetes mellitus, Adv. Exp. Med. Biol., 1307, 299, 10.1007/5584_2020_487 Kwon, 2021, Serum glucose excretion after Roux-en-Y gastric bypass: a potential target for diabetes treatment, Gut, 70, 1847, 10.1136/gutjnl-2020-321402 Lancaster, 2014, Organogenesis in a dish: modeling development and disease using organoid technologies, Science, 345, 10.1126/science.1247125 Langhans, 2018, Three-dimensional in vitro cell culture models in drug discovery and drug repositioning, Front. Pharmacol., 9, 6, 10.3389/fphar.2018.00006 Lanik, 2018, Stem cell-derived models of viral infections in the gastrointestinal tract, Viruses, 10, 124, 10.3390/v10030124 Le, 2014, A collagen-based multicellular tumor spheroid model for evaluation of the efficiency of nanoparticle drug delivery, Artif. Cell Nanomed. Biotechnol., 44, 540, 10.3109/21691401.2014.968820 Leslie, 2015, Persistence and toxin production by clostridium difficile within human intestinal organoids result in disruption of epithelial paracellular barrier function, Infect. Immun., 83, 138, 10.1128/IAI.02561-14 Li, 2021, Volumetric compression induces intracellular crowding to control intestinal organoid growth via Wnt/β-catenin signaling, Cell Stem Cell, 28, 63, 10.1016/j.stem.2020.09.012 Lin, 2021, Polysaccharides isolated from Laminaria japonica attenuates gestational diabetes mellitus by regulating the gut microbiota in mice, Food Frontiers, 2, 208, 10.1002/fft2.79 Liu, 2018, Modeling human diseases with induced pluripotent stem cells: from 2D to 3D and beyond, Development, 145, 10.1242/dev.156166 Loomans, 2018, Expansion of adult human pancreatic tissue yields organoids harboring progenitor cells with endocrine differentiation potential, Stem Cell Rep., 10, 712, 10.1016/j.stemcr.2018.02.005 Ma, 2018, β Cell replacement after gene editing of a neonatal diabetes-causing mutation at the insulin locus, Stem Cell Rep., 11, 1407, 10.1016/j.stemcr.2018.11.006 Manzar, 2017, Demethylation of induced pluripotent stem cells from type 1 diabetic patients enhances differentiation into functional pancreatic β cells, J. Biol. Chem., 292, 14066, 10.1074/jbc.M117.784280 Matano, 2015, Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids, Nat. Med., 21, 256, 10.1038/nm.3802 McCauley, 2017, Pluripotent stem cell-derived organoids: using principles of developmental biology to grow human tissues in a dish, Development, 144, 958, 10.1242/dev.140731 McCracken, 2011, Generating human intestinal tissue from pluripotent stem cells in vitro, Nat. Protoc., 6, 1920, 10.1038/nprot.2011.410 Meran, 2017, Intestinal stem cell niche: the extracellular matrix and cellular components, Stem Cells Int. 2017, 10.1155/2017/7970385 Miller, 2019, Generation of lung organoids from human pluripotent stem cells in vitro, Nat. Protoc., 14, 518, 10.1038/s41596-018-0104-8 Millman, 2016, Generation of stem cell-derived β-cells from patients with type 1 diabetes, Nat. Commun., 7 Neal, 2018, Organoid modeling of the tumor immune microenvironment, Cell, 175, 1972, 10.1016/j.cell.2018.11.021 Nusse, 2017, Wnt/β-Catenin signaling, disease, and emerging therapeutic modalities, Cell, 169, 985, 10.1016/j.cell.2017.05.016 Pak, 2021, Organoids: expanding applications enabled by emerging technologies: organoids: emerging technologies and applications, J. Mol. Biol., 434, 10.1016/j.jmb.2021.167411 Park, 2019, Organoids-on-a-chip, Science, 364, 960, 10.1126/science.aaw7894 Pellegrinelli, 2014, Endothelial cells from visceral adipose tissue disrupt adipocyte functions in a three-dimensional setting: partial rescue by angiopoietin-1, Diabetes, 63, 535, 10.2337/db13-0537 Pellegrini, 2017, Duodenal mucosa of patients with type 1 diabetes shows distinctive inflammatory profile and microbiota, J. Clin. Endocrinol. Metabol., 102, 1468, 10.1210/jc.2016-3222 Ravi, 2015, 3D cell culture systems: advantages and applications, J. Cell. Physiol., 230, 16, 10.1002/jcp.24683 Rhee, 2015, Effect of Roux-en-Y gastric bypass on the distribution and hormone expression of small-intestinal enteroendocrine cells in obese patients with type 2 diabetes, Diabetologia, 58, 2254, 10.1007/s00125-015-3696-3 Saarimäki-Vire, 2017, An activating STAT3 mutation causes neonatal diabetes through premature induction of pancreatic differentiation, Cell Rep., 19, 281, 10.1016/j.celrep.2017.03.055 Sato, 2011, Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and barrette's epithelium, Gastroenterology, 141, 1762, 10.1053/j.gastro.2011.07.050 Sato, 2009, Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche, Nature, 459, 262, 10.1038/nature07935 Siljander, 2019, Microbiome and type 1 diabetes, EBioMedicine, 46, 512, 10.1016/j.ebiom.2019.06.031 Sinagoga, 2015, Generating human intestinal tissues from pluripotent stem cells to study development and disease, EMBO J., 34, 1149, 10.15252/embj.201490686 Smits, 2020, Midbrain organoids: a new tool to investigate Parkinson's disease, Front. Cell Dev. Biol., 8, 359, 10.3389/fcell.2020.00359 Spence, 2011, Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro, Nature, 470, 105, 10.1038/nature09691 Spit, 2018, Tales from the crypt: intestinal niche signals in tissue renewal, plasticity and cancer, Open Biol., 8, 10.1098/rsob.180120 Sugimoto, 2021, An organoid-based organ-repurposing approach to treat short bowel syndrome, Nature, 592, 99 Svendsen, 2016, Regulation of gut hormone secretion. Studies using isolated perfused intestines, Peptides, 77, 47, 10.1016/j.peptides.2015.08.001 Takebe, 2017, Synergistic engineering: organoids meet organs-on-a-chip, Cell Stem Cell, 21, 297, 10.1016/j.stem.2017.08.016 Takebe, 2014, Generation of a vascularized and functional human liver from an ipsc-derived organ bud transplant, Nat. Protoc., 9, 396, 10.1038/nprot.2014.020 Talchai, 2015, Legacy effect of Foxo1 in pancreatic endocrine progenitors on adult β-cell mass and function, Diabetes, 64, 2868, 10.2337/db14-1696 Thomson, 1998, Embryonic stem cell lines derived from human blastocysts, Science, 282, 1145, 10.1126/science.282.5391.1145 Tsakmaki, 2020, Diabetes through a 3D lens: organoid models, Diabetologia, 63, 1093, 10.1007/s00125-020-05126-3 Tsakmaki, 2017, 3D intestinal organoids in metabolic research: virtual reality in a dish, Curr. Opin. Pharmacol., 37, 51, 10.1016/j.coph.2017.09.003 Tsakmaki, 2020, Diabetes through a 3D lens: organoid models, Diabetologia, 63, 1093, 10.1007/s00125-020-05126-3 Wells, 2014, How to make an intestine, Development, 141, 752, 10.1242/dev.097386 Xu, 2020, Faecalibacterium prausnitzii-derived microbial anti-inflammatory molecule regulates intestinal integrity in diabetes mellitus mice via modulating tight junction protein expression, J. Diabetes, 12, 224, 10.1111/1753-0407.12986 Yang, 2021, Role of the gut microbiota in type 2 diabetes and related diseases, Metabolism, 117, 10.1016/j.metabol.2021.154712 Yang, 2020, A 3D culture platform enables development of zinc-binding prodrugs for targeted proliferation of β cells, Sci. Adv., 6, 10.1126/sciadv.abc3207 Yin, 2019, Mini-gut: a promising model for drug development, Drug Discov. Today, 24, 1784, 10.1016/j.drudis.2019.06.006 Yin, 2019, Enteroids for nutritional studies, Mol. Nutr. Food Res., 63, 10.1002/mnfr.201801143 Yin, 2019, Enteroids: promising in vitro models for studies of intestinal physiology and nutrition in farm animals, J. Agric. Food Chem., 67, 2421, 10.1021/acs.jafc.8b06908 Zhang, 2020, 3D organoids derived from the small intestine: an emerging tool for drug transport research, Acta Pharm. Sin. B, 11, 1697, 10.1016/j.apsb.2020.12.002 Zhao, 2020, miRNAs as regulators of antidiabetic effects of fucoidans, eFood, 1, 2, 10.2991/efood.k.190822.001 Zhao, 2020, Intestinal stem cells and intestinal organoids, J. Genet. Genom., 47, 289, 10.1016/j.jgg.2020.06.005 Zietek, 2015, Intestinal nutrient sensing and blood glucose control, Curr. Opin. Clin. Nutr. Metab. Care, 18, 381, 10.1097/MCO.0000000000000187 Zietek, 2020, Organoids to study intestinal nutrient transport, drug uptake and metabolism - update to the human model and expansion of applications, Front. Bioeng. Biotechnol., 8, 10.3389/fbioe.2020.577656 Zietek, 2015, Intestinal organoids for assessing nutrient transport, sensing and incretin secretion, Sci. Rep., 5, 10.1038/srep16831 Zizmare, 2022, Roux-En-Y Gastric Bypass (RYGB) surgery during high liquid sucrose diet leads to gut microbiota-related systematic alterations, Int. J. Mol. Sci., 23, 1126, 10.3390/ijms23031126