A 28-day oral toxicity evaluation of small interfering RNAs and a long double-stranded RNA targeting vacuolar ATPase in mice
Tài liệu tham khảo
Altschul, 1990, Basic local alignment search tool, J. Mol. Biol., 215, 403, 10.1016/S0022-2836(05)80360-2
Aulbach, A., 2013. Assessing toxicity of the hematologic system in preclinical safety studies. MPI Laboratories Presentation, March 6, 2013. Adam Aulbach, DVM, DACVP, Director of Clinical Pathology.
Baum, 2007, Control of coleopteran insect pests through RNA interference, Nat. Biotechnol., 25, 1322, 10.1038/nbt1359
Behlke, 2006, Progress towards in vivo use of siRNAs, Mol. Ther., 13, 644, 10.1016/j.ymthe.2006.01.001
Christensen, 2013, Metabolism studies of unformulated internally [3H]-labeled short interfering RNAs in mice, Drug Metab. Dispos., 41, 1211, 10.1124/dmd.112.050666
Cottrill, 2014, Diet-derived MicroRNAs: separating the dream from reality, microRNA Diagn. Ther., 1, 46
Della Vedova, 2005, The dominant inhibitory chalcone synthase allele C2-Idf (inhibitor diffuse) from Zea mays (L.) acts via an endogenous RNA silencing mechanism, Genetics, 170, 1989, 10.1534/genetics.105.043406
Dickinson, 2013, Lack of detectable oral bioavailability of plant microRNAs after feeding in mice, Nat. Biotechnol., 31, 965, 10.1038/nbt.2737
Dunnett, 1955, A multiple comparison procedure for comparing several treatments with a control, J. Am. Statist. Assoc., 50, 1096, 10.1080/01621459.1955.10501294
Dunnett, 1964, New tables for multiple comparisons with a control, Biometrics, 20, 482, 10.2307/2528490
Elliott, G., 2011. Hematology. Global Preclinical Training Institute, Clinical Pathology Course for Toxicologists, June 2011, South Lake Tahoe, Nevada. Glenn Elliott, DVM, DACVP, Charles River Laboratories.
Forbes, 2012, Oral delivery of small RNA and DNA, J. Control Release., 162, 438, 10.1016/j.jconrel.2012.06.037
Frizzi, 2010, Tapping RNA silencing pathways for plant biotechnology, Plant Biotechnol. J., 8, 655, 10.1111/j.1467-7652.2010.00505.x
Fukuhara, 2006, The wide distribution of endornaviruses, large double-stranded RNA replicons with plasmid-like properties, Arch. Virol., 151, 995, 10.1007/s00705-005-0688-5
Gantier, 2007, The response of mammalian cells to double-stranded RNA, Cytokine Growth Factor Rev., 18, 363, 10.1016/j.cytogfr.2007.06.016
Gilmore, 2004, The design and exogenous delivery of siRNA for post-transcriptional gene silencing, J. Drug Target., 12, 315, 10.1080/10611860400006257
Gish, 1993, Identification of protein coding regions by database similarity search, Nat. Genet., 3, 266, 10.1038/ng0393-266
Gould, 1981, Immunochemical detection of ds-RNA in healthy and virus-infected plants and specific detection of viral ds-RNA by hybridization to labelled complementary DNA, J. Virol. Methods, 2, 277, 10.1016/0166-0934(81)90026-4
Hammond, 2005, Dicing and slicing: the core machinery of the RNA interference pathway, FEBS Lett., 579, 5822, 10.1016/j.febslet.2005.08.079
Hannus, 2014, SiPools: highly complex but accurately defined siRNA pools eliminate off-target effects, Nucleic Acids Res., 10.1093/nar/gku480
Heisel, 2008, Characterization of unique small RNA populations from rice grain, PLoS One, 3, e2871, 10.1371/journal.pone.0002871
Hollander, 1973
Houck, 1958, The microdetermination of ribonuclease, Arch. Biochem. Biophys., 73, 384, 10.1016/0003-9861(58)90283-2
Huvenne, 2010, Mechanisms of dsRNA uptake in insects and potential of RNAi for pest control: a review, J. Insect Physiol., 56, 227, 10.1016/j.jinsphys.2009.10.004
Ivashuta, 2009, Endogenous small RNAs in grain: semi-quantification and sequence homology to human and animal genes, Food Chem. Toxicol., 47, 353, 10.1016/j.fct.2008.11.025
Jackson, 2003, Expression profiling reveals off-target gene regulation by RNAi, Nat. Biotechnol., 21, 635, 10.1038/nbt831
Jefferies, 2008, Function, structure and regulation of the vacuolar (H+)-ATPases, Arch. Biochem. Biophys., 476, 33, 10.1016/j.abb.2008.03.025
Jensen, 2013, Computational sequence analysis of predicted long dsRNA transcriptomes of major crops reveals sequence complementarity with human genes, GM Crops Food., 4, 90, 10.4161/gmcr.25285
Juliano, 2009, Biological barriers to therapy with antisense and siRNA oligonucleotides, Mol. Pharm., 6, 686, 10.1021/mp900093r
Li, 2005, Methylation protects miRNAs and siRNAs from a 3′-end uridylation activity in Arabidopsis, Curr. Biol., 15, 1501, 10.1016/j.cub.2005.07.029
Liu, 2013, The effect of regions flanking target site on siRNA potency, Genomics, 102, 215, 10.1016/j.ygeno.2013.07.009
Liu, 2009, Dicer-like (DCL) proteins in plants, Funct. Integr. Genomics, 9, 277, 10.1007/s10142-009-0111-5
Molitoris, 2009, siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury, J. Am. Soc. Nephrol., 20, 1754, 10.1681/ASN.2008111204
Nguyen, 2008, RNAi therapeutics: an update on delivery, Curr. Opin. Mol. Ther., 10, 158
Nicklin, 1998, Pulmonary bioavailability of a phosphorothioate oligonucleotide (CGP 64128A): comparison with other delivery routes, Pharm. Res., 15, 583, 10.1023/A:1011934011690
O’Neill, 2011, Intestinal delivery of non-viral gene therapeutics: physiological barriers and preclinical models, Drug Discov. Today, 16, 203, 10.1016/j.drudis.2011.01.003
Parrott, 2010, Application of food and feed safety assessment principles to evaluate transgenic approaches to gene modulation in crops, Food Chem. Toxicol., 48, 1773, 10.1016/j.fct.2010.04.017
Petrick, 2013, Safety assessment of food and feed from biotechnology-derived crops employing RNA-mediated gene regulation to achieve desired traits: a scientific review, Regul. Toxicol. Pharmacol., 66, 167, 10.1016/j.yrtph.2013.03.008
Raoof, 2004, Oral bioavailability and multiple dose tolerability of an antisense oligonucleotide tablet formulated with sodium caprate, J. Pharm. Sci., 93, 1431, 10.1002/jps.20051
Ryu, 2005, Differential regulation of hepatic gene expression by starvation versus refeeding following a high-sucrose or high-fat diet, Nutrition, 21, 543, 10.1016/j.nut.2005.01.001
Siomi, 2009, On the road to reading the RNA-interference code, Nature, 457, 396, 10.1038/nature07754
Snedecor, 1967
Snow, 2013, Ineffective delivery of diet-derived microRNAs to recipient animal organisms, RNA Biol., 10, 1107, 10.4161/rna.24909
Thompson, 2012, Toxicological and pharmacokinetic properties of chemically modified siRNAs targeting p53 RNA following intravenous administration, Nucleic Acid Therapeut., 22, 255, 10.1089/nat.2012.0371
Tillman, 2008, Oral delivery of antisense oligonucleotides in man, J. Pharm Sci., 97, 225, 10.1002/jps.21084
Tosar, 2014, Mining of public sequencing databases supports a non-dietary origin for putative foreign miRNAs: underestimated effects of contamination in NGS, RNA, 20, 1, 10.1261/rna.044263.114
Tuteja, 2004, Tissue-specific gene silencing mediated by a naturally occurring chalcone synthase gene cluster in Glycine max, Plant Cell., 16, 819, 10.1105/tpc.021352
Vaishnaw, 2010, A status report on RNAi therapeutics, Silence, 1, 14, 10.1186/1758-907X-1-14
Witwer, 2013, Real-time quantitative PCR and droplet digital PCR for plant miRNAs in mammalian blood provide little evidence for general uptake of dietary miRNAs: limited evidence for general uptake of dietary plant xenomiRs, RNA Biol., 10, 1080, 10.4161/rna.25246
Yates, 2013, The long and short of microRNA, Cell, 153, 516, 10.1016/j.cell.2013.04.003
Zamore, 2000, RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals, Cell, 101, 25, 10.1016/S0092-8674(00)80620-0
Zhang, 2012, Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA, Cell Res., 22, 107, 10.1038/cr.2011.158
Zhang, 2012, Analysis of plant-derived miRNAs in animal small RNA datasets, BMC Genomics, 13, 381, 10.1186/1471-2164-13-381