Aβ-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Aβ pathology

Neuroscience Research - Tập 43 - Trang 39-56 - 2002
Shinjiro Fukami1,2, Kaori Watanabe1, Nobuhisa Iwata1, Jo Haraoka2, Bao Lu3, Norma P. Gerard3, Craig Gerard3, Paul Fraser4,5, David Westaway4,6, Peter St. George-Hyslop4,7,8, Takaomi C. Saido1
1Laboratory for Proteolytic Neuroscience, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan
2Department of Neurosurgery, Tokyo Medical University, Shinjuku, Tokyo 160-0023, Japan
3Department of Pediatrics and Medicine, Harvard Medical School, Boston, MA 02115, USA
4Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ont., Canada M5S 1A1
5Department of Medical Biophysics, University of Toronto, Toronto, Ont., Canada M5S 1A1
6Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ont., Canada M5S 1A1
7Department of Medicine, University of Toronto, Toronto, Ont., Canada M5S 1A1
8Division of Neurology, Department of Medicine, University Health Network, Toronto, Ont., Canada

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Neuroscience Research

Tập 43

39-56

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