Mechanisms of oxidative stress in methylmercury-induced neurodevelopmental toxicity
Tài liệu tham khảo
Al Osman, 2019, Exposure routes and health effects of heavy metals on children, Biometals, 32, 563, 10.1007/s10534-019-00193-5
Alexandrov, 2018, Synergism in aluminum and mercury neurotoxicity, Integr. Food Nutr. Metab., 5
Ali, 2018, Natural dietary supplementation of anthocyanins via pi3k/akt/nrf2/ho-1 pathways mitigate oxidative stress, neurodegeneration, and memory impairment in a mouse model of alzheimer’s disease, Mol. Neurobiol., 55, 6076, 10.1007/s12035-017-0798-6
Al-Osaimi, 2018, Therapeutic and protective potency of bee pollen against neurotoxic effects induced by prenatal exposure of rats to methyl mercury, J. Mol. Neurosci., 65, 327, 10.1007/s12031-018-1107-1
Al-Saleh, 2016, Alterations in biochemical markers due to mercury (hg) exposure and its influence on infant’s neurodevelopment, Int. J. Hyg. Environ. Health, 219, 898, 10.1016/j.ijheh.2016.07.002
Antunes Dos Santos, 2018, Oxidative stress in methylmercury-induced cell toxicity, Toxics, 6
Aschner, 2007, Involvement of glutamate and reactive oxygen species in methylmercury neurotoxicity, Braz. J. Med. Biol. Res., 40, 285, 10.1590/S0100-879X2007000300001
Bakir, 1973, Methylmercury poisoning in iraq, Science, 181, 230, 10.1126/science.181.4096.230
Baraldi, 2002, Cognitive deficits and changes in gene expression of nmda receptors after prenatal methylmercury exposure, Environ. Health Perspect., 110, 855, 10.1289/ehp.02110s5855
Ben Bacha, 2020, The therapeutic and protective effects of bee pollen against prenatal methylmercury induced neurotoxicity in rat pups, Metab. Brain Dis., 35, 215, 10.1007/s11011-019-00496-z
Berezovska, 1999, Notch1 inhibits neurite outgrowth in postmitotic primary neurons, Neuroscience, 93, 433, 10.1016/S0306-4522(99)00157-8
Bjørklund, 2017, The toxicology of mercury: current research and emerging trends, Environ. Res., 159, 545, 10.1016/j.envres.2017.08.051
Björklund, 2007, The effects of methylmercury on motor activity are sex- and age-dependent, and modulated by genetic deletion of adenosine receptors and caffeine administration, Toxicology, 241, 119, 10.1016/j.tox.2007.08.092
Black, 2011, Modulation of the effects of methylmercury on rat neurodevelopment by co-exposure with labrador tea (rhododendron tomentosum ssp. Subarcticum), Food Chem. Toxicol., 49, 2336, 10.1016/j.fct.2011.06.035
Bland, 2006, Methylmercury induces activation of notch signaling, Neurotoxicology, 27, 982, 10.1016/j.neuro.2006.04.005
Bose, 2012, Inherited effects of low-dose exposure to methylmercury in neural stem cells, Toxicol. Sci., 130, 383, 10.1093/toxsci/kfs257
Boucher, 2012, Prenatal methylmercury, postnatal lead exposure, and evidence of attention deficit/hyperactivity disorder among inuit children in arctic quebec, Environ. Health Perspect., 120, 1456, 10.1289/ehp.1204976
Branco, 2017, Biomarkers of mercury toxicity: past, present, and future trends, J. Toxicol. Environ. Health B Crit. Rev., 20, 119, 10.1080/10937404.2017.1289834
Bridges, 2017, Mechanisms involved in the transport of mercuric ions in target tissues, Arch. Toxicol., 91, 63, 10.1007/s00204-016-1803-y
Caballero, 2017, Methylmercury-induced developmental toxicity is associated with oxidative stress and cofilin phosphorylation. Cellular and human studies, Neurotoxicology, 59, 197, 10.1016/j.neuro.2016.05.018
Cambier, 2018, A likely placental barrier against methylmercury in pregnant rats exposed to fish-containing diets, Food Chem. Toxicol., 122, 11, 10.1016/j.fct.2018.09.066
Carratù, 2006, Acute exposure to methylmercury at two developmental windows: focus on neurobehavioral and neurochemical effects in rat offspring, Neuroscience, 141, 1619, 10.1016/j.neuroscience.2006.05.017
Ceccatelli, 2010, Methylmercury-induced neurotoxicity and apoptosis, Chem. Biol. Interact., 188, 301, 10.1016/j.cbi.2010.04.007
Chang, 2013, Methylmercury induces caspase-dependent apoptosis and autophagy in human neural stem cells, J. Toxicol. Sci., 38, 823, 10.2131/jts.38.823
Chang, 2015, Activation of sonic hedgehog signaling enhances cell migration and invasion by induction of matrix metalloproteinase-2 and -9 via the phosphoinositide-3 kinase/akt signaling pathway in glioblastoma, Mol. Med. Rep., 12, 6702, 10.3892/mmr.2015.4229
Chang, 2019, Plant components can reduce methylmercury toxication: a mini-review, Biochim. Biophys. Acta Gen. Subj., 1863, 10.1016/j.bbagen.2019.01.012
Charton, 1999, Cellular and subcellular localization of the 2b-subunit of the nmda receptor in the adult rat telencephalon, Brain Res., 816, 609, 10.1016/S0006-8993(98)01243-8
Chen, 2014, Curcumin increased the differentiation rate of neurons in neural stem cells via wnt signaling in vitro study, J. Surg. Res., 192, 298, 10.1016/j.jss.2014.06.026
Cheng, 2001, Rat glutathione s-transferase m4-4: an isoenzyme with unique structural features including a redox-reactive cysteine-115 residue that forms mixed disulphides with glutathione, Biochem. J., 356, 403, 10.1042/bj3560403
Cheng, 2013, Neurobehavioral effects, c-fos/jun expression and tissue distribution in rat offspring prenatally co-exposed to mehg and pfoa: pfoa impairs hg retention, Chemosphere, 91, 758, 10.1016/j.chemosphere.2013.02.016
Cheng, 2015, Assessing pre/post-weaning neurobehavioral development for perinatal exposure to low doses of methylmercury, J. Environ. Sci. (China), 38, 36, 10.1016/j.jes.2015.05.027
Choi, 1978, Abnormal neuronal migration, deranged cerebral cortical organization, and diffuse white matter astrocytosis of human fetal brain: a major effect of methylmercury poisoning in utero, J. Neuropathol. Exp. Neurol., 37, 719, 10.1097/00005072-197811000-00001
Cialfi, 2014, Loss of notch1-dependent p21(waf1/cip1) expression influences the notch1 outcome in tumorigenesis, Cell Cycle, 13, 2046, 10.4161/cc.29079
Clarkson, 2002, The three modern faces of mercury, Environ. Health Perspect., 110, 11, 10.1289/ehp.02110s111
Cohen, 2005, A quantitative analysis of prenatal intake of n-3 polyunsaturated fatty acids and cognitive development, Am. J. Prev. Med., 29, 366, 10.1016/j.amepre.2005.06.008
Cosentino-Gomes, 2012, Cell signaling through protein kinase c oxidation and activation, Int. J. Mol. Sci., 13, 10697, 10.3390/ijms130910697
Costa, 2004, Developmental neuropathology of environmental agents, Annu. Rev. Pharmacol. Toxicol., 44
Dansen, 2009, Redox-sensitive cysteines bridge p300/cbp-mediated acetylation and foxo4 activity, Nat. Chem. Biol., 5, 664, 10.1038/nchembio.194
Daré, 2001, Methylmercury and h(2)o(2) provoke lysosomal damage in human astrocytoma d384 cells followed by apoptosis, Free Radic. Biol. Med., 30, 1347, 10.1016/S0891-5849(01)00526-3
Daré, 2003, Effects of prenatal exposure to methylmercury on dopamine-mediated locomotor activity and dopamine d2 receptor binding, Naunyn Schmiedebergs Arch. Pharmacol., 367, 500, 10.1007/s00210-003-0716-5
Debes, 2006, Impact of prenatal methylmercury exposure on neurobehavioral function at age 14 years, Neurotoxicol. Teratol., 28, 363, 10.1016/j.ntt.2006.02.004
Denu, 2016, Effects of oxidative stress on mesenchymal stem cell biology, Oxid. Med. Cell. Longev., 2016, 10.1155/2016/2989076
Deroma, 2013, Neuropsychological assessment at school-age and prenatal low-level exposure to mercury through fish consumption in an italian birth cohort living near a contaminated site, Int. J. Hyg. Environ. Health, 216, 486, 10.1016/j.ijheh.2013.02.004
Eliasson, 2010, The hematopoietic stem cell niche: low in oxygen but a nice place to be, J. Cell. Physiol., 222, 17, 10.1002/jcp.21908
Engel, 2014, The notch target e(spl)mδ is a muscle-specific gene involved in methylmercury toxicity in motor neuron development, Neurotoxicol. Teratol., 43, 11, 10.1016/j.ntt.2014.03.001
Erdogan, 2018, Midkine downregulation increases the efficacy of quercetin on prostate cancer stem cell survival and migration through pi3k/akt and mapk/erk pathway, Biomed. Pharmacother., 107, 793, 10.1016/j.biopha.2018.08.061
Espitia-Pérez, 2018, Neurobehavioral and oxidative stress alterations following methylmercury and retinyl palmitate co-administration in pregnant and lactating rats and their offspring, Neurotoxicology, 69, 164, 10.1016/j.neuro.2018.10.004
Falluel-Morel, 2012, N-acetyl cysteine treatment reduces mercury-induced neurotoxicity in the developing rat hippocampus, J. Neurosci. Res., 90, 743, 10.1002/jnr.22819
Fang, 2005, The mapk signalling pathways and colorectal cancer, Lancet Oncol., 6, 322, 10.1016/S1470-2045(05)70168-6
Farina, 2017, Methylmercury-induced neurotoxicity: focus on pro-oxidative events and related consequences, Adv. Neurobiol., 18, 267, 10.1007/978-3-319-60189-2_13
Farina, 2019, Glutathione antioxidant system and methylmercury-induced neurotoxicity: an intriguing interplay, Biochim. Biophys. Acta Gen. Subj., 1863, 10.1016/j.bbagen.2019.01.007
Farina, 2011, Oxidative stress in mehg-induced neurotoxicity, Toxicol. Appl. Pharmacol., 256, 405, 10.1016/j.taap.2011.05.001
Faustman, 2002, Investigations of methylmercury-induced alterations in neurogenesis, Environ. Health Perspect., 110, 859, 10.1289/ehp.02110s5859
Forsyth, 2006, Physiologic oxygen enhances human embryonic stem cell clonal recovery and reduces chromosomal abnormalities, Cloning Stem Cells, 8, 16, 10.1089/clo.2006.8.16
Franco, 2006, Cerebellar thiol status and motor deficit after lactational exposure to methylmercury, Environ. Res., 102, 22, 10.1016/j.envres.2006.02.003
Franco, 2007, Mercurial-induced hydrogen peroxide generation in mouse brain mitochondria: protective effects of quercetin, Chem. Res. Toxicol., 20, 1919, 10.1021/tx7002323
Franco, 2009, Methylmercury neurotoxicity is associated with inhibition of the antioxidant enzyme glutathione peroxidase, Free Radic. Biol. Med., 47, 449, 10.1016/j.freeradbiomed.2009.05.013
Fujimura, 2018, Methylmercury induces oxidative stress and subsequent neural hyperactivity leading to cell death through the p38 mapk-creb pathway in differentiated sh-sy5y cells, Neurotoxicology, 67, 226, 10.1016/j.neuro.2018.06.008
Fujimura, 2020, Methylmercury-mediated oxidative stress and activation of the cellular protective system, Antioxidants (Basel), 9
Fujimura, 2009, Methylmercury exposure downregulates the expression of racl and leads to neuritic degeneration and ultimately apoptosis in cerebrocortical neurons, Neurotoxicology, 30, 16, 10.1016/j.neuro.2008.10.002
Fujimura, 2009, Methylmercury induces neuropathological changes with tau hyperphosphorylation mainly through the activation of the c-jun-n-terminal kinase pathway in the cerebral cortex, but not in the hippocampus of the mouse brain, Neurotoxicology, 30, 1000, 10.1016/j.neuro.2009.08.001
Gao, 2008, Effects of methylmercury on postnatal neurobehavioral development in mice, Neurotoxicol. Teratol., 30, 462, 10.1016/j.ntt.2008.07.004
Grandjean, 2011, Methylmercury and brain development: imprecision and underestimation of developmental neurotoxicity in humans, Mt. Sinai J. Med., 78, 107, 10.1002/msj.20228
Grandjean, 1997, Cognitive deficit in 7-year-old children with prenatal exposure to methylmercury, Neurotoxicol. Teratol., 19, 417, 10.1016/S0892-0362(97)00097-4
Granitzer, 2021, Amino acid transporter lat1 (slc7a5) mediates mehg-induced oxidative stress defense in the human placental cell line htr-8/svneo, Int. J. Mol. Sci., 22
Gray, 1995, A physiologically based pharmacokinetic model for methyl mercury in the pregnant rat and fetus, Toxicol. Appl. Pharmacol., 132, 91, 10.1006/taap.1995.1090
Gribble, 2005, The magnitude of methylmercury-induced cytotoxicity and cell cycle arrest is p53-dependent, Birth Defects Res. Part A Clin. Mol. Teratol., 73, 29, 10.1002/bdra.20104
Hahn, 2015, Nrf2 and nrf2-related proteins in development and developmental toxicity: insights from studies in zebrafish (danio rerio), Free Radic. Biol. Med., 88, 275, 10.1016/j.freeradbiomed.2015.06.022
Han, 2008, Sirt1 regulates apoptosis and nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization, Cell Stem Cell, 2, 241, 10.1016/j.stem.2008.01.002
Hashemi, 2016, Synthesis and cyto-genotoxicity evaluation of graphene on mice spermatogonial stem cells, Colloids Surf. B Biointerfaces, 146, 770, 10.1016/j.colsurfb.2016.07.019
Hassan, 2012, The effect of methylmercury exposure on early central nervous system development in the zebrafish (danio rerio) embryo, J. Appl. Toxicol., 32, 707, 10.1002/jat.1675
Heimfarth, 2018, Developmental neurotoxicity of the hippocampus following in utero exposure to methylmercury: impairment in cell signaling, Arch. Toxicol., 92, 513, 10.1007/s00204-017-2042-6
Holben, 1999, The diverse role of selenium within selenoproteins: a review, J. Am. Diet. Assoc., 99, 836, 10.1016/S0002-8223(99)00198-4
Huang, 2011, Neurotoxicological effects of low-dose methylmercury and mercuric chloride in developing offspring mice, Toxicol. Lett., 201, 196, 10.1016/j.toxlet.2010.12.016
Imayoshi, 2011, The role of notch signaling in adult neurogenesis, Mol. Neurobiol., 44, 7, 10.1007/s12035-011-8186-0
Inaba, 2009, Porphyromonas gingivalis invades human trophoblasts and inhibits proliferation by inducing g1 arrest and apoptosis, Cell. Microbiol., 11, 1517, 10.1111/j.1462-5822.2009.01344.x
Inaba, 2018, Cell cycle arrest and apoptosis induced by porphyromonas gingivalis require jun n-terminal protein kinase- and p53-mediated p38 activation in human trophoblasts, Infect. Immun., 86
Itoh, 1999, Regulatory mechanisms of cellular response to oxidative stress, Free Radic. Res., 31, 319, 10.1080/10715769900300881
Jacob, 2019, Extenuation of in utero toxic effects of mehg in the developing neurons by fisetin via modulating the expression of synaptic transmission and plasticity regulators in hippocampus of the rat offspring, Chem. Biol. Interact., 305
Jacob, 2017, Effect of gestational intake of fisetin (3,3’,4’,7-tetrahydroxyflavone) on developmental methyl mercury neurotoxicity in f generation rats, Biol. Trace Elem. Res., 177, 297, 10.1007/s12011-016-0886-x
Jacob, 2018, Fisetin impedes developmental methylmercury neurotoxicity via downregulating apoptotic signalling pathway and upregulating rho gtpase signalling pathway in hippocampus of f generation rats, Int. J. Dev. Neurosci., 69, 88, 10.1016/j.ijdevneu.2018.07.002
Janssen-Heininger, 2008, Redox-based regulation of signal transduction: principles, pitfalls, and promises, Free Radic. Biol. Med., 45
Jomova, 2010, Metals, oxidative stress and neurodegenerative disorders, Mol. Cell. Biochem., 345
Joshi, 2014, Reversal of methylmercury-induced oxidative stress, lipid peroxidation, and DNA damage by the treatment of n-acetyl cysteine: a protective approach, J. Environ. Pathol. Toxicol. Oncol., 33, 167, 10.1615/JEnvironPatholToxicolOncol.2014010291
Karri, 2018, An in vitro cytotoxic approach to assess the toxicity of heavy metals and their binary mixtures on hippocampal ht-22 cell line, Toxicol. Lett., 282, 25, 10.1016/j.toxlet.2017.10.002
Kaur, 2006, Glutathione modulation influences methyl mercury induced neurotoxicity in primary cell cultures of neurons and astrocytes, Neurotoxicology, 27, 492, 10.1016/j.neuro.2006.01.010
Ke, 2019, Post-translational modifications in mehg-induced neurotoxicity, Biochim. Biophys. Acta Mol. Basis Dis., 1865, 2068, 10.1016/j.bbadis.2018.10.024
Khan, 2003, Developmental changes in murine brain antioxidant enzymes, Pediatr. Res., 54, 77, 10.1203/01.PDR.0000065736.69214.20
Kim, 2007, The inhibitory mechanism of methylmercury on differentiation of human neuroblastoma cells, Toxicology, 234, 1, 10.1016/j.tox.2007.01.003
Kim, 2016, Hypoxia suppresses spontaneous mineralization and osteogenic differentiation of mesenchymal stem cells via igfbp3 up-regulation, Int. J. Mol. Sci., 17, 10.3390/ijms17091389
Kingham, 2009, Distinct roles for isoforms of the catalytic subunit of class-ia pi3k in the regulation of behaviour of murine embryonic stem cells, J. Cell. Sci., 122, 2311, 10.1242/jcs.046557
Kishi, 2017, The hokkaido birth cohort study on environment and children’s health: cohort profile-updated 2017, Environ. Health Prev. Med., 22, 46, 10.1186/s12199-017-0654-3
Kondo, 2005, Pkc/mapk signaling suppression by retinal pericyte conditioned medium prevents retinal endothelial cell proliferation, J. Cell. Physiol., 203, 378, 10.1002/jcp.20237
Kumagai, 2013, The role of the keap1/nrf2 pathway in the cellular response to methylmercury, Oxid. Med. Cell. Longev., 2013, 10.1155/2013/848279
Laplante, 2012, Mtor signaling in growth control and disease, Cell, 149, 274, 10.1016/j.cell.2012.03.017
Laugeray, 2018, Perinatal exposure to the cyanotoxin beta-n-methylamino-l-alanine (bmaa) results in long-lasting behavioral changes in offspring-potential involvement of DNA damage and oxidative stress, Neurotox. Res., 33, 87, 10.1007/s12640-017-9802-1
Lee, 2017, Adverse effects of methylmercury (mehg) on life parameters, antioxidant systems, and mapk signaling pathways in the rotifer brachionus koreanus and the copepod paracyclopina nana, Aquat. Toxicol., 190, 181, 10.1016/j.aquatox.2017.07.006
Li, 2019, Curcumin promotes proliferation of adult neural stem cells and the birth of neurons in alzheimer’s disease mice via notch signaling pathway, Cell. Reprogram., 21, 152, 10.1089/cell.2018.0027
Li, 2020, High cholesterol induces apoptosis and autophagy through the ros-activated akt/foxo1 pathway in tendon-derived stem cells, Stem Cell Res. Ther., 11, 131, 10.1186/s13287-020-01643-5
Liang, 2014, Stem cells, redox signaling, and stem cell aging, Antioxid. Redox Signal., 20, 1902, 10.1089/ars.2013.5300
Liu, 2017, Memantine, a low-affinity nmda receptor antagonist, protects against methylmercury-induced cytotoxicity of rat primary cultured cortical neurons, involvement of ca dyshomeostasis antagonism, and indirect antioxidation effects, Mol. Neurobiol., 54, 5034, 10.1007/s12035-016-0020-2
Liu, 2017, Memantine, a low-affinity nmda receptor antagonist, protects against methylmercury-induced cytotoxicity of rat primary cultured cortical neurons, involvement of ca(2+) dyshomeostasis antagonism, and indirect antioxidation effects, Mol. Neurobiol., 54, 5034, 10.1007/s12035-016-0020-2
Liu, 2019, Methyl-mercury induces apoptosis through ros-mediated endoplasmic reticulum stress and mitochondrial apoptosis pathways activation in rat cortical neurons, Free Radic. Res., 53, 26, 10.1080/10715762.2018.1546852
Lohren, 2016, Effects on and transfer across the blood-brain barrier in vitro-comparison of organic and inorganic mercury species, BMC Pharmacol. Toxicol., 17, 63, 10.1186/s40360-016-0106-5
Lu, 2009, Selenoproteins, J. Biol. Chem., 284, 723, 10.1074/jbc.R800045200
Lu, 2011, Involvement of oxidative stress-mediated erk1/2 and p38 activation regulated mitochondria-dependent apoptotic signals in methylmercury-induced neuronal cell injury, Toxicol. Lett., 204, 71, 10.1016/j.toxlet.2011.04.013
Lucena, 2010, Cipura paludosa attenuates long-term behavioral deficits in rats exposed to methylmercury during early development, Ecotoxicol. Environ. Saf., 73, 1150, 10.1016/j.ecoenv.2010.04.008
Lucena, 2013, Ethanolic extract from bulbs of cipura paludosa reduced long-lasting learning and memory deficits induced by prenatal methylmercury exposure in rats, Dev. Cogn. Neurosci., 3
Maia, 2009, Interference of ethanol and methylmercury in the developing central nervous system, Neurotoxicology, 30, 23, 10.1016/j.neuro.2008.11.008
Manfroi, 2004, Maternal milk as methylmercury source for suckling mice: neurotoxic effects involved with the cerebellar glutamatergic system, Toxicol. Sci., 81, 172, 10.1093/toxsci/kfh201
Marchiani, 2014, Curcumin and curcumin-like molecules: from spice to drugs, Curr. Med. Chem., 21, 204, 10.2174/092986732102131206115810
Marty, 1997, Pathways mediating ca2+ entry in rat cerebellar granule cells following in vitro exposure to methyl mercury, Toxicol. Appl. Pharmacol., 147, 319, 10.1006/taap.1997.8262
McCubrey, 2007, Roles of the raf/mek/erk pathway in cell growth, malignant transformation and drug resistance, Biochim. Biophys. Acta, 1773, 1263, 10.1016/j.bbamcr.2006.10.001
Melov, 1999, Mitochondrial disease in superoxide dismutase 2 mutant mice, Proc. Natl. Acad. Sci. U. S. A., 96, 846, 10.1073/pnas.96.3.846
Mendoza, 2002, P21(waf1/cip1) inhibits cell cycle progression but not g2/m-phase transition following methylmercury exposure, Toxicol. Appl. Pharmacol., 178, 117, 10.1006/taap.2001.9267
Merchant, 2011, The redox-sensitive transcription factor nrf2 regulates murine hematopoietic stem cell survival independently of ros levels, Blood, 118, 6572, 10.1182/blood-2011-05-355362
Miyamoto, 2001, Involvement of enhanced sensitivity of n-methyl-d-aspartate receptors in vulnerability of developing cortical neurons to methylmercury neurotoxicity, Brain Res., 901, 252, 10.1016/S0006-8993(01)02281-8
Miyashita, 2015, Effects of in utero exposure to polychlorinated biphenyls, methylmercury, and polyunsaturated fatty acids on birth size, Sci. Total Environ., 533, 256, 10.1016/j.scitotenv.2015.06.108
Myers, 2003, Prenatal methylmercury exposure from ocean fish consumption in the seychelles child development study, Lancet, 361, 1686, 10.1016/S0140-6736(03)13371-5
Nava, 2000, Melatonin attenuates acute renal failure and oxidative stress induced by mercuric chloride in rats, Am. J. Physiol. Renal Physiol., 279, F910, 10.1152/ajprenal.2000.279.5.F910
Ng, 2015, Mercury, apoe, and child behavior, Chemosphere, 120, 123, 10.1016/j.chemosphere.2014.06.003
Ni, 2011, Comparative study on the response of rat primary astrocytes and microglia to methylmercury toxicity, Glia, 59, 810, 10.1002/glia.21153
Nishigaki, 1975, Methylmercury and selenium in umbilical cords of inhabitants of the minamata area, Nature, 258, 324, 10.1038/258324a0
Nishioku, 2000, Involvement of caspase 3-like protease in methylmercury-induced apoptosis of primary cultured rat cerebral microglia, Brain Res., 871, 160, 10.1016/S0006-8993(00)02436-7
Nogara, 2019, Methylmercury’s chemistry: from the environment to the mammalian brain, Biochim. Biophys. Acta Gen. Subj., 1863, 10.1016/j.bbagen.2019.01.006
Olguín, 2018, Neurotransmitter amines and antioxidant agents in neuronal protection against methylmercury-induced cytotoxicity in primary cultures of mice cortical neurons, Neurotoxicology, 69, 278, 10.1016/j.neuro.2018.07.020
Orrenius, 2011, Cell death mechanisms and their implications in toxicology, Toxicol. Sci., 119
Ou, 1999, Induction of the cell cycle regulatory gene p21 (waf1, cip1) following methylmercury exposure in vitro and in vivo, Toxicol. Appl. Pharmacol., 157, 203, 10.1006/taap.1999.8685
Ou, 2018, Physiologically based pharmacokinetic (pbpk) modeling of human lactational transfer of methylmercury in china, Environ. Int., 115, 180, 10.1016/j.envint.2018.03.018
Paithankar, 2021, Heavy metal associated health hazards: an interplay of oxidative stress and signal transduction, Chemosphere, 262, 10.1016/j.chemosphere.2020.128350
Paletz, 2006, Gestational exposure to methylmercury and n-3 fatty acids: effects on high- and low-rate operant behavior in adulthood, Neurotoxicol. Teratol., 28, 59, 10.1016/j.ntt.2005.11.003
Paling, 2004, Regulation of embryonic stem cell self-renewal by phosphoinositide 3-kinase-dependent signaling, J. Biol. Chem., 279, 48063, 10.1074/jbc.M406467200
Papp, 2007, From selenium to selenoproteins: synthesis, identity, and their role in human health, Antioxid. Redox Signal., 9, 775, 10.1089/ars.2007.1528
Patel, 2013, Methylmercury impairs motor function in early development and induces oxidative stress in cerebellar granule cells, Toxicol. Lett., 222, 265, 10.1016/j.toxlet.2013.08.002
Peyvandi, 2018, Deferoxamine promotes mesenchymal stem cell homing in noise-induced injured cochlea through pi3k/akt pathway, Cell Prolif., 51, 10.1111/cpr.12434
Pierozan, 2017, Neurotoxicity of methylmercury in isolated astrocytes and neurons: the cytoskeleton as a main target, Mol. Neurobiol., 54, 5752, 10.1007/s12035-016-0101-2
Pinho, 2017, Antioxidant and mercury chelating activity of psidium guajava var. Pomifera l. Leaves hydroalcoholic extract, J. Toxicol. Environ. Health A, 80, 1301, 10.1080/15287394.2017.1382408
Prince, 2017, Notch target gene e(spl)mδ is a mediator of methylmercury-induced myotoxicity in drosophila, Front. Genet., 8, 233, 10.3389/fgene.2017.00233
Raciti, 2019, Nrxn1 deletion and exposure to methylmercury increase astrocyte differentiation by different notch-dependent transcriptional mechanisms, Front. Genet., 10, 593, 10.3389/fgene.2019.00593
Ramkissoon, 2013, Developmental role of nuclear factor e2-related factor 2 in mitigating methamphetamine fetal toxicity and postnatal neurodevelopmental deficits, Free Radic. Biol. Med., 65, 620, 10.1016/j.freeradbiomed.2013.07.043
Ray, 2012, Reactive oxygen species (ros) homeostasis and redox regulation in cellular signaling, Cell. Signal., 24, 981, 10.1016/j.cellsig.2012.01.008
Rodrigues, 2019, Aqueous coriandrum sativum l. Extract promotes neuroprotection against motor changes and oxidative damage in rat progeny after maternal exposure to methylmercury, Food Chem. Toxicol., 133, 10.1016/j.fct.2019.110755
Rothenberg, 2011, Low-level maternal methylmercury exposure through rice ingestion and potential implications for offspring health, Environ. Pollut., 159, 1017, 10.1016/j.envpol.2010.12.024
Ryu, 2015, Regulation of stem cell fate by ros-mediated alteration of metabolism, Int. J. Stem Cells, 8, 24, 10.15283/ijsc.2015.8.1.24
Sakamoto, 2002, Evaluation of changes in methylmercury accumulation in the developing rat brain and its effects: a study with consecutive and moderate dose exposure throughout gestation and lactation periods, Brain Res., 949, 51, 10.1016/S0006-8993(02)02964-5
Sanders, 2015, Perinatal and childhood exposure to cadmium, manganese, and metal mixtures and effects on cognition and behavior: a review of recent literature, Curr. Environ. Health Rep., 2, 284, 10.1007/s40572-015-0058-8
Sargis, 2006, Protection of membrane cholesterol by sphingomyelin against free radical-mediated oxidation, Free Radic. Biol. Med., 40, 2092, 10.1016/j.freeradbiomed.2006.02.005
Savickiene, 1999, Modulation of apoptosis of proliferating and differentiating hl-60 cells by protein kinase inhibitors: suppression of pkc or pka differently affects cell differentiation and apoptosis, Cell Death Differ., 6, 698, 10.1038/sj.cdd.4400541
Sethi, 2009, Curcumin attenuates aluminium-induced functional neurotoxicity in rats, Pharmacol. Biochem. Behav., 93, 31, 10.1016/j.pbb.2009.04.005
Sfakianakis, 2015, Effect of heavy metals on fish larvae deformities: a review, Environ. Res., 137, 246, 10.1016/j.envres.2014.12.014
Shimura, 2017, A comparison of radiation-induced mitochondrial damage between neural progenitor stem cells and differentiated cells, Cell Cycle, 16, 565, 10.1080/15384101.2017.1284716
Simon, 2008, The role of oxygen availability in embryonic development and stem cell function, Nat. Rev. Mol. Cell Biol., 9, 285, 10.1038/nrm2354
Sirois, 2000, Methylmercury affects multiple subtypes of calcium channels in rat cerebellar granule cells, Toxicol. Appl. Pharmacol., 167
Snoj Tratnik, 2017, Prenatal mercury exposure, neurodevelopment and apolipoprotein e genetic polymorphism, Environ. Res., 152, 375, 10.1016/j.envres.2016.08.035
Sobolewski, 2018, Endocrine active metals, prenatal stress and enhanced neurobehavioral disruption, Horm. Behav., 101, 36, 10.1016/j.yhbeh.2018.01.004
Steinbrenner, 2009, Protection against reactive oxygen species by selenoproteins, Biochim. Biophys. Acta, 1790, 1478, 10.1016/j.bbagen.2009.02.014
Steuerwald, 2000, Maternal seafood diet, methylmercury exposure, and neonatal neurologic function, J. Pediatr., 136, 599, 10.1067/mpd.2000.102774
Straka, 2016, Mercury toxicokinetics of the healthy human term placenta involve amino acid transporters and abc transporters, Toxicology, 340, 34, 10.1016/j.tox.2015.12.005
Stringari, 2008, Prenatal methylmercury exposure hampers glutathione antioxidant system ontogenesis and causes long-lasting oxidative stress in the mouse brain, Toxicol. Appl. Pharmacol., 227, 147, 10.1016/j.taap.2007.10.010
Su, 2019, Reactive oxygen species-induced lipid peroxidation in apoptosis, autophagy, and ferroptosis, Oxid. Med. Cell. Longev., 2019, 10.1155/2019/5080843
Suzuki, 2015, Molecular basis of the keap1-nrf2 system, Free Radic. Biol. Med., 88
Takahashi, 2017, Methylmercury causes blood-brain barrier damage in rats via upregulation of vascular endothelial growth factor expression, PLoS One, 12, 10.1371/journal.pone.0170623
Takahata, 2009, Functional expression of beta2 adrenergic receptors responsible for protection against oxidative stress through promotion of glutathione synthesis after nrf2 upregulation in undifferentiated mesenchymal c3h10t1/2 stem cells, J. Cell. Physiol., 218, 268, 10.1002/jcp.21594
Tamm, 2008, Methylmercury inhibits differentiation of rat neural stem cells via notch signalling, Neuroreport, 19, 339, 10.1097/WNR.0b013e3282f50ca4
Tatsuta, 2017, Psychomotor ability in children prenatally exposed to methylmercury: the 18-month follow-up of tohoku study of child development, Tohoku J. Exp. Med., 242, 1, 10.1620/tjem.242.1
Tofighi, 2011, Non-dioxin-like polychlorinated biphenyls interfere with neuronal differentiation of embryonic neural stem cells, Toxicol. Sci., 124, 192, 10.1093/toxsci/kfr221
Toyama, 2007, Cytoprotective role of nrf2/keap1 system in methylmercury toxicity, Biochem. Biophys. Res. Commun., 363, 645, 10.1016/j.bbrc.2007.09.017
Uchikawa, 2011, Chlorella suppresses methylmercury transfer to the fetus in pregnant mice, J. Toxicol. Sci., 36, 675, 10.2131/jts.36.675
Valko, 2005, Metals, toxicity and oxidative stress, Curr. Med. Chem., 12, 1161, 10.2174/0929867053764635
Vejrup, 2018, Prenatal mercury exposure, maternal seafood consumption and associations with child language at five years, Environ. Int., 110, 71, 10.1016/j.envint.2017.10.008
Villaseñor, 2017, Region-specific permeability of the blood-brain barrier upon pericyte loss, J. Cereb. Blood Flow Metab., 37, 3683, 10.1177/0271678X17697340
Wagner, 2010, In vivo and in vitro inhibition of mice thioredoxin reductase by methylmercury, Biometals, 23, 1171, 10.1007/s10534-010-9367-4
Wagner, 2010, Comparative study of quercetin and its two glycoside derivatives quercitrin and rutin against methylmercury (mehg)-induced ros production in rat brain slices, Arch. Toxicol., 84, 89, 10.1007/s00204-009-0482-3
Wakabayashi, 2010, Regulation of notch1 signaling by nrf2: implications for tissue regeneration, Sci. Signal., 3
Wakabayashi, 2015, Crosstalk between nrf2 and notch signaling, Free Radic. Biol. Med., 88, 158, 10.1016/j.freeradbiomed.2015.05.017
Wang, 2009, Trichosanthin suppresses hela cell proliferation through inhibition of the pkc/mapk signaling pathway, Cell Biol. Toxicol., 25, 479, 10.1007/s10565-008-9102-x
Wang, 2013, Redox homeostasis: the linchpin in stem cell self-renewal and differentiation, Cell Death Dis., 4, e537, 10.1038/cddis.2013.50
Wang, 2014, Postnatal exposure to methyl mercury and neuropsychological development in 7-year-old urban inner-city children exposed to lead in the united states, Child Neuropsychol., 20, 527, 10.1080/09297049.2013.824955
Wang, 2016, Low-dose methylmercury-induced apoptosis and mitochondrial DNA mutation in human embryonic neural progenitor cells, Oxid. Med. Cell. Longev., 2016, 10.1155/2016/5137042
Wang, 2016, Low-dose methylmercury-induced genes regulate mitochondrial biogenesis via mir-25 in immortalized human embryonic neural progenitor cells, Int. J. Mol. Sci., 17
Wang, 2018, Curcumin pretreatment prevents hydrogen peroxide-induced oxidative stress through enhanced mitochondrial function and deactivation of akt/erk signaling pathways in rat bone marrow mesenchymal stem cells, Mol. Cell. Biochem., 443, 37, 10.1007/s11010-017-3208-5
Wang, 2019, Curcumin pretreatment protects against hypoxia/reoxgenation injury via improvement of mitochondrial function, destabilization of hif-1α and activation of epac1-akt pathway in rat bone marrow mesenchymal stem cells, Biomed. Pharmacother., 109, 1268, 10.1016/j.biopha.2018.11.005
Yan, 1997, Oxidative damage during aging targets mitochondrial aconitase, Proc. Natl. Acad. Sci. U. S. A., 94, 11168, 10.1073/pnas.94.21.11168
Yang, 2016, Protective effects of alpha-lipoic acid on mehg-induced oxidative damage and intracellular ca(2+) dyshomeostasis in primary cultured neurons, Free Radic. Res., 50, 542, 10.3109/10715762.2016.1152362
Yang, 2019, Curcumin protects against methylmercury-induced cytotoxicity in primary rat astrocytes by activating the nrf2/are pathway independently of pkcδ, Toxicology, 425, 10.1016/j.tox.2019.152248
Yoshida, 2014, Neurobehavioral changes in response to alterations in gene expression profiles in the brains of mice exposed to low and high levels of mercury vapor during postnatal development, J. Toxicol. Sci., 39, 561, 10.2131/jts.39.561
Yu, 2016, Proliferation, survival and metabolism: the role of pi3k/akt/mtor signalling in pluripotency and cell fate determination, Development, 143, 3050, 10.1242/dev.137075
Zareba, 2007, Thimerosal distribution and metabolism in neonatal mice: comparison with methyl mercury, J. Appl. Toxicol., 27, 511, 10.1002/jat.1272
Zhang, 2016, Ros and ros-mediated cellular signaling, Oxid. Med. Cell. Longev., 2016, 10.1155/2016/4350965
Zhang, 2018, Hydrogen ameliorates oxidative stress via pi3k-akt signaling pathway in uvb-induced hacat cells, Int. J. Mol. Med., 41, 3653
Zhang, 2020, Neuroprotective effects of astaxanthin against oxygen and glucose deprivation damage via the pi3k/akt/gsk3β/nrf2 signalling pathway in vitro, J. Cell. Mol. Med.
Zhuang, 2019, Resveratrol attenuates oxidative stress-induced intestinal barrier injury through pi3k/akt-mediated nrf2 signaling pathway, Oxid. Med. Cell. Longev., 2019, 10.1155/2019/7591840
Zou, 2014, Nrf2 is involved in maintaining hepatocyte identity during liver regeneration, PLoS One, 9, 10.1371/journal.pone.0107423