The cardiac sarcolemmal ATP-sensitive potassium channel as a novel target for anti-arrhythmic therapy
Tài liệu tham khảo
Abildstrom, 1999, Epidemiology of arrhythmic and sudden death in the chronic phase of ischemic heart disease, Cardiac Electrophysiol Rev, 3, 177, 10.1023/A:1009971104937
Aguilar-Bryan, 1995, Cloning of the beta cell high affinity sulfonylurea receptor: a regulator of insulin secretion, Science, 268, 423, 10.1126/science.7716547
1997, Effects of prophylactic amiodarone on mortality after acute myocardial infarction and in congestive heart failure: meta-analysis of individual data from 6500 patients in randomized trials, Lancet, 350, 1417, 10.1016/S0140-6736(97)05281-1
Aronson, 2003, Effects of sulfonylurea agents and adenosine triphosphate dependent potassium channel antagonists on ventricular arrhythmias in patients with decompensated heart failure, PACE, 26, 1254, 10.1046/j.1460-9592.2003.t01-1-00177.x
Baczko, 1997, KATP channel modulators increase survival rate during coronary occlusion-reperfusion in anaesthetized rats, Eur J Pharmacol, 324, 77, 10.1016/S0014-2999(97)00064-2
Barrett, 1998, Glibenclamide does not prevent action potential shortening induced by ischemia in anesthetized rabbits but reduces ischemia-induced arrhythmias, J Mol Cell Cardiol, 30, 999, 10.1006/jmcc.1998.0664
Bayes de Luna, 1989, Ambulatory sudden cardiac death: mechanisms of production of fatal arrhythmia on the basis of data from 157 cases, Am Heart J, 117, 151, 10.1016/0002-8703(89)90670-4
Behrens, 2001, Influence of a new ATP-sensitive potassium-channel antagonist (HMR 1098) on ventricular fibrillation inducibility during myocardial ischemia, Eur Heart J, 22, 546
Bekheit, 1990, Effects of glyburide on ischemia-induced changes in extracellular potassium and local myocardial activation: a potential new approach to the management of ischemia-induced malignant ventricular arrhythmias, Am Heart J, 119, 1025, 10.1016/S0002-8703(05)80231-5
Bellemin-Baurreau, 1994, Effects of ATP-dependent K+ channel modulators on an ischemia–reperfusion rabbit isolated heart model with programmed electrical stimulation, Eur J Pharmacol, 256, 115, 10.1016/0014-2999(94)90235-6
Benndorf, 1991, Anoxia opens ATP regulated K channels in isolated heart cells of the guinea pig, Pflugers Arch, 419, 108, 10.1007/BF00373754
Billman, 1991, The antiarrhythmic and antifibrillatory effects of calcium antagonists, J Cardiovasc Pharmacol, 18, S107, 10.1097/00005344-199118101-00019
Billman, 1992, Ro 40-5967, a novel calcium channel antagonist protects against ventricular fibrillation, Eur J Pharmacol, 229, 179, 10.1016/0014-2999(92)90553-G
Billman, 1995, The effect of a novel calcium channel antagonist, mibefradil, on refractory period and arrhythmias induced by programmed electrical stimulation and myocardial ischemia: a comparison with diltiazem and verapmil, J Pharmacol Exp Therap, 277, 1517
Billman, 1993, The effects of the ATP-dependent potassium channel antagonist glyburide on coronary blood flow and susceptibility to ventricular fibrillation, J Cardiovasc Pharmacol, 21, 197, 10.1097/00005344-199302000-00003
Billman, 1994, The role of the ATP-sensitive K+ channel in K+ accumulation and cardiac arrhythmias during myocardial ischemia, Cardiovasc Res, 28, 762, 10.1093/cvr/28.6.762
Billman, 1998, HMR 1883, a novel cardioselective inhibitor of the ATP- sensitive potassium channel; Part II: effects on susceptibility to ventricular fibrillation induced by myocardial ischemia in conscious dogs, J Pharmacol Exp Therap, 286, 1465
Billman, 1999, Ischemically-induced changes in the T-wave and susceptibility to sudden death: evidence that activation of the ATP-sensitive potassium channel may contribute to ventricular fibrillation, Circulation, 100, I
Billman, 2001, Selective sarcolemmal, but not selective mitochondrial, ATP-sensitive potassium channel antagonists prevent ventricular fibrillation induced by ischaemia, Eur Heart J, 22, 246
Billman, 2004, Effects of a novel cardioselective ATP-sensitive potassium channel antagonist 1-[[5-[2(5-chloro-o-anisamido)ethyl]-β-methoxyethoxyphenyl]sulfonyl]-3-methylthioura, sodium salt (HMR 1402), on susceptibility to ventricular fibrillation induced by myocardial ischemia: in vitro and in vivo studies, J Pharmacol Exp Therap, 309, 182, 10.1124/jpet.103.061416
Bohn, 1998, The KATP channel blocker HMR 1883 attenuates the effects of ischemia on MAP duration and improves survival during LAD occlusion in anaesthetized pig, Br J Pharmacol, 124, 23P
Bril, 1992, Effects of glibenclamide on ventricular arrhythmias and cardiac function in ischaemia and reperfusion in isolated rat heart, Cardiovasc Res, 26, 1069, 10.1093/cvr/26.11.1069
Buxton, 1999, A randomized study of the prevention of sudden death in patients with coronary artery disease, N Engl J Med, 341, 1882, 10.1056/NEJM199912163412503
Cacciapuoti, 1991, Effectiveness of glibenclamide on myocardial ischemic ventricular arrhythmias in non-insulin dependent diabetes mellitus, Am J Cardiol, 67, 843, 10.1016/0002-9149(91)90617-T
Chi, 1993, Actions of pinacidil at a reduced potassium concentration — a direct cardiac effect possibly involving the ATP-sensitive potassium channel, J Cardiovasc Pharmacol, 21, 179, 10.1097/00005344-199302000-00001
Chi, 1990, Profibrillatory actions of pinacidil in a conscious canine model of sudden coronary death, J Cardiovasc Pharmacol, 15, 452, 10.1097/00005344-199003000-00016
Chutkow, 2001, Disruption of Sur2-containg KATP channels enhances insulin-stimulated glucose uptake in skeletal muscle, Proc Natl Acad Sci (USA), 98, 11760, 10.1073/pnas.201390398
Colatsky, 1990, Channel specificity in antiarrhythmic drug action. Mechanism of potassium channel block and its role in suppressing and aggravating cardiac arrhythmias, Circulation, 82, 2235, 10.1161/01.CIR.82.6.2235
Coromilas, 2002, Effects of pinacidil on electrophysiological properties of epicardial border zone of healing canine infarcts: possible effects of KATP channel activation, Circulation, 105, 2309, 10.1161/01.CIR.0000016292.14390.16
Coronel, 1988, Distribution of extracellular potassium and its relation to electrophysiologic changes during acute myocardial ischemia in the isolated perfused porcine heart, Circulation, 77, 1125, 10.1161/01.CIR.77.5.1125
Coronel, 1995, Heterogeneities in [K+]o and TQ potential and the inducibility of ventricular fibrillation during acute regional ischemia in the isolated perfused porcine heart, Circulation, 92, 120, 10.1161/01.CIR.92.1.120
Coronel, 1991, Injury current and gradients of diastolic stimulation threshold, TQ potential, and extracellular potassium concentration during acute regional ischemia in the isolated perfused pig heart, Circ Res, 68, 1241, 10.1161/01.RES.68.5.1241
Curtis, 1991, The rabbit dual coronary perfusion model: a new method for assessing pathological relevance of individual products of the ischaemeic milieu: role of potassium in arrhythmogenesis, Cardiovasc Res, 25, 1010, 10.1093/cvr/25.12.1010
Curtis, 1993, Endogenous chemical mediators of ventricular arrythmias in ischaemic heart disease, Cardiovasc Res, 27, 703, 10.1093/cvr/27.5.703
D'Alonzo, 1998, Proarrhythmic effects of pinacidil are partially meditated through enhancement of catecholamine release in isolated perfused guinea-pig hearts, J Mol Cell Cardiol, 30, 415, 10.1006/jmcc.1997.0605
Das, 2005, Is the sarcolemmal or mitochondrial KATP channel activation important in the antiarrhythmic and cardioprotective effects during acute ischemia/reperfusion in the intact anesthetized rabbit model?, Life Science, 77, 1226, 10.1016/j.lfs.2004.12.042
Davis, 1998, Arrhythmias and mortality after myocardial infarction in diabetic patients. Relationship to diabetes treatment, Diabetes Care, 21, 637, 10.2337/diacare.21.4.637
del Valle, 2001, Glibenclamide effects reperfusion-induced malignant arrhythmias and left ventricular mechanical recovery from stunning in conscious sheep, Cardiovasc Res, 50, 474, 10.1016/S0008-6363(01)00209-7
Deutsch, 1991, Activation of cardiac ATP-sensitive K+ current during hypoxia: correlation with tissue ATP levels, Am J Physiol Heart Circ Physiol, 261, H671, 10.1152/ajpheart.1991.261.3.H671
Dhein, 2000, Effects of the IK.ATP blockers glibenclamide and HMR1883 on cardiac electrophysiology during ischemia and reperfusion, Eur J Pharmacol, 398, 273, 10.1016/S0014-2999(00)00322-8
Di Diego, 1993, Pinacidil-induced electrical heterogeneity and extrasystolic activity in canine ventricular tissues. Does activation of ATP-regulated potassium current promote phase 2 reentry, Circulation, 88, 1177, 10.1161/01.CIR.88.3.1177
Dunne, 1986, Intracellular ADP activates K+ channels that are inhibited by ATP in an insulin secreting cell line, FEBS Lett, 208, 59, 10.1016/0014-5793(86)81532-0
Echt, 1991, Mortality and morbidity in patients receiving encainide, flecainide, or placebo, N Engl J Med, 324, 782, 10.1056/NEJM199103213241201
Edwards, 1993, The pharmacology of ATP-sensitive potassium channels, Ann Rev Pharmacol Toxicol, 33, 597, 10.1146/annurev.pa.33.040193.003121
El Reyani, 1999, Comparison of the efficacy of glibenclamide and glimepiride in reperfusion-induced arrhythmias in rats, Eur J Pharmacol, 365, 187, 10.1016/S0014-2999(98)00866-8
Englert, 2001, Cardioselective K(ATP) channel blockers derived from a new series of m-anisamidoethylbenzenesulfonylthioureas, J Med Chem, 44, 1085, 10.1021/jm000985v
Englert, 2003, Blockers of the ATP-sensitive potassium channel SURA/Kir6.2: a new approach to prevent sudden cardiac death, Curr Med Chem, 1, 253
Faivre, 1990, Action potential duration and activation of ATP-sensitive potassium current in isolated guinea-pig ventricular myocytes, Biochim Biophys Acta, 1029, 167, 10.1016/0005-2736(90)90450-3
Findlay, 1988, ATP4- and ATP.Mg inhibit the ATP-sensitive K+ channel of rat ventricular myocytes, Pflugers Arch, 412, 37, 10.1007/BF00583729
Fischbach, 2004, Risk of ventricular proarrhythmia with the selective opening of the myocardial sarcolemmal versus mitochondrial ATP-gated potassium channel, J Pharmacol Exp Ther, 309, 554, 10.1124/jpet.103.060780
Flagg, 2005, Sarcolemmal KATP channels: what do we really know?, J Mol Cell Cardiol, 39, 61, 10.1016/j.yjmcc.2005.01.005
Flagg, 2007, Arrhythmia susceptibility and premature death in transgenic mice overexpressing both SUR1 and Kir6.2[DN30,K185Q] in the heart, Am J Physiol Heart Circ Physiol, 293, H836, 10.1152/ajpheart.00011.2007
Fosset, 1988, Antidiabetic sulfonylureas control action potential properties in heart cells via high affinity receptors that are linked to ATP- dependent K+ channels, J Biol Chem, 263, 7933, 10.1016/S0021-9258(18)68422-4
Foster, 2008, Is Kir6.1 a subunit of mitoKATP?, Biochem Biophys Res Comm, 266, 649, 10.1016/j.bbrc.2007.11.154
Friedel, 1990, Pinacidil — a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the treatment of hypertension, Drugs, 39, 929, 10.2165/00003495-199039060-00008
Fryer, 2000, Ischemic preconditioning in rats: role of mitochondrial KATP channel in preservation of mitochondrial function, Am J Physiol Heart Circ Physiol, 278, H305, 10.1152/ajpheart.2000.278.1.H305
Furukawa, 1991, Role of cardiac ATP-regulated potassium channels in differential responses of endocardial and epicardial cells to ischemia, Circ Res, 68, 1693, 10.1161/01.RES.68.6.1693
Gilmour, 1980, Different electrophysiological responses of canine endocardium and epicardium to combined hyperkalemia, hypoxia, and acidosis, Circ Res, 46, 814, 10.1161/01.RES.46.6.814
Gillum, 1989, Sudden coronary death in the United States 1980–1985, Circulation, 79, 756, 10.1161/01.CIR.79.4.756
Gögelein, 2001, Inhibition of cardiac ATP-dependent potassium channels by sulfonylurea drugs, Curr Opin Invest Drugs, 2, 71
Gögelein, 1999, Molecular basis, pharmacology and physiological role of cardiac KATP channels, Cell Physiol Biochem, 9, 227, 10.1159/000016319
Gögelein, 1998, HMR 1883, a novel cardioselective inhibitor of the ATP-sensitive potassium channel. Part I: effects on cardiomyocytes, coronary flow and pancreatic beta-cells, J Pharmacol Exp Ther, 286, 1453
Gok, 2006, Effects of the blockade of cardiac sarcolemmal ATP-sensitive potassium channels on arrhythmias and coronary flow in ischemia–reperfusion model in isolated rat hearts, Vasc Pharmacol, 44, 197, 10.1016/j.vph.2005.11.006
Goldberg, 1988, Clinical pharmacology of pinacidil, a prototype for drugs that affect potassium channels, J Cardiovasc Pharmacol, 12, S41, 10.1097/00005344-198812002-00008
Gong, 2000, A KATP channel deficiency affects resting tension, not contractile force, during fatigue in skeletal muscle, Am J Physiol, 279, C1351, 10.1152/ajpcell.2000.279.5.C1351
Gopalakrishnan, 1999, Characterization of the ATP-sensitive potassium channels (K-ATP) expressed in guinea pig bladder smooth muscle cells, J Pharmacol Exp Ther, 289, 551
Greene, 1990, Sudden arrhythmic cardiac death: mechanisms, resuscitation and classification: the Seattle perspective, Am J Cardiol, 65, 4B, 10.1016/0002-9149(90)91285-E
Gribble, 2003, Sulphonylurea action revisited: the post-cloning era, Diabetologia, 46, 875, 10.1007/s00125-003-1143-3
Gribble, 1997, The essential role of Walker A motifs of SUR1 in K-ATP channel activation by MgADP and diazoxide, EMBO J, 16, 1145, 10.1093/emboj/16.6.1145
Gribble, 1998, Tissue specificity of sulfonylureas: studies on cloned cardiac and beta-cell KATP channels, Diabetes, 47, 1412, 10.2337/diabetes.47.9.1412
Gross, 1999, Sarcolemmal versus mitochondrial ATP-sensitive K+ channels and myocardial preconditioning, Circ Res, 84, 973, 10.1161/01.RES.84.9.973
Grover, 2000, ATP-sensitive potassium channels: a review of their cardioprotective pharmacology, J Mol Cell Cardiol, 32, 677, 10.1006/jmcc.2000.1111
Grover, 2001, Pharmacologic characterization of BMS-191095, a mitochondrial KATP opener with no peripheral vosaodilator or cardiac action potential shortening activity, J Phamacol Exp Ther, 297, 1184
Grover, 2002, In vivo characterization of the mitochondrial selective KATP opener (3R)-trans-4-((4-chlorophenyl)-N-(1H-imidazol-2-ylmethyl)dimethyl-2H-1-benzopyran-6-carbonitril monohydrochloride (BMS-191095): cardioprotective, hemodynamic, and electrophysiological effects, J Pharmacol Exp Ther, 303, 132, 10.1124/jpet.102.036988
Gwilt, 1992, Effects of drugs on ventricular fibrillation and ischaemic K+ loss in a model of ischaemia in perfused guinea-pig hearts in vitro, Eur J Pharmacol, 220, 231, 10.1016/0014-2999(92)90752-P
Hamada, 1998, Shortening of monophasic action potential duration during hyperkalemia and myocardial ischemia in anesthetized dogs, Jpn J Pharmacol, 76, 149, 10.1254/jjp.76.149
Harris, 1966, Potassium and experimental coronary occlusion, Am Heart J, 71, 797, 10.1016/0002-8703(66)90601-6
Harris, 1954, Excitory factors in ventricular tachycardia resulting from myocardial ischemia: potassium a major excitant, Science, 119, 200, 10.1126/science.119.3085.200
Haworth, 1989, Inhibition of ATP-sensitive potassium channels of adult rat heart cells by antiarrhythmic drugs, Circ Res, 65, 1157, 10.1161/01.RES.65.4.1157
Held, 1989, Early intravenous beta-blockade in acute myocardial infarction, Cardiology, 76, 132, 10.1159/000174484
Held, 1993, Effects of beta-blockers and Ca2+ channel blockers in acute myocardial infarction, Eur Heart J, 14, 18, 10.1093/eurheartj/14.suppl_F.18
Hicks, 1991, Effect of glibenclamide on extracellular potassium accumulation and the electrophysiological changes during myocardial ischaemia in the arterially perfused interventricular septum of rabbit, Cardiovasc Res, 25, 407, 10.1093/cvr/25.5.407
Hill, 1980, Effect of acute coronary artery occlusion on local myocardial extracellular K+ activity in swine, Circulation, 61, 768, 10.1161/01.CIR.61.4.768
Hinkle, 1982, Clinical classification of cardiac deaths, Circulation, 65, 457, 10.1161/01.CIR.65.3.457
Holmes, 2000, Amiodarone inhibits cardiac ATP-sensitive potassium channels, J Cardiovasc Electrophysiol, 11, 1152, 10.1111/j.1540-8167.2000.tb01762.x
Hondeghem, 1987, Antiarrhythmic agents: modulated receptor applications, Circulation, 75, 514, 10.1161/01.CIR.75.3.514
Hondeghem, 1978, Reproducible and uniform cardiac ischemia: effects of antiarrhythmic drugs, Am J Physiol Heart Circ Physiol, 235, H574, 10.1152/ajpheart.1978.235.5.H574
Huizar, 2003, Sulfonylureas attenuate electrocardiographic ST-segment elevations during acute myocardial infarction in diabetics, J Am Coll Cardiol, 42, 1017, 10.1016/S0735-1097(03)00916-1
Inagaki, 1995, Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor, Science, 270, 1166, 10.1126/science.270.5239.1166
Johnson, 1991, Magnitude and time course of extracellular potassium inhomogeneities during acute ischemia in pigs. Effect of verapamil, Circulation, 83, 622, 10.1161/01.CIR.83.2.622
Jung, 2000, The KATP channel blocker HMR 1883 does not abolish the benefit of ischemic preconditioning on myocardial infarct mass in anesthetized rabbits, Naunyn Schmiedebergs Arch Pharmacol, 361, 445, 10.1007/s002109900212
Kaab, 2003, Selective block of sarcolemmal IKATP in human cardiomycytes using HMR 1098, Cardiovasc Drug Therap, 17, 435, 10.1023/B:CARD.0000015858.34009.0c
Kakei, 1986, The ATP-sensitivity of K+ channels in rat pancreatic β-cells is modulated by ADP, FEBS Lett, 208, 63, 10.1016/0014-5793(86)81533-2
Kanda, 1997, Unanticipated lessening of the rise in extracellular potassium during ischemia by pinacidil, Circulation, 95, 1937, 10.1161/01.CIR.95.7.1937
Kantor, 1990, Reduction of ischemic K+ loss and arrhythmias in rat hearts: effect of glibenclamide, a sulfonylurea, Circ Res, 66, 478, 10.1161/01.RES.66.2.478
Kempsford, 1989, Assessment of the antiarrhythmic activity of nicorandil during myocardial ischemia and reperfusion, Eur J Pharmacol, 163, 61, 10.1016/0014-2999(89)90395-6
Kendall, 1995, β-Blockers and sudden cardiac death, Ann Intern Med, 123, 353, 10.7326/0003-4819-123-5-199509010-00007
Kimura, 1986, Simultaneous recording of action potentials from endocardium and epicardium during ischemia in the isolated cat ventricle: relation of temporal electrophysiologic heterogeneities to arrhythmias, Circulation, 74, 401, 10.1161/01.CIR.74.2.401
Kleber, 1983, Resting membrane potential, extracellular potassium activity, and intracellular sodium activity during acute global ischemia in isolated perfused guinea pig hearts, Circ Res, 52, 442, 10.1161/01.RES.52.4.442
Kleber, 1984, Extracellular potassium accumulation in acute myocardial ischemia, J Mol Cell Cardiol, 16, 389, 10.1016/S0022-2828(84)80610-0
Kondo, 1996, Glibenclamide attenuates peaked T wave in early phase of myocardial ischemia, Cardiovasc Res, 31, 683, 10.1016/S0008-6363(96)00016-8
Koster, 2005, Diabetes and insulin secretion the ATP-sensitive K+ Channel (KATP) connection, Diabetes, 54, 3065, 10.2337/diabetes.54.11.3065
Koumi, 1997, Alterations in ATP-sensitive potassium channel sensitivity to ATP in failing human hearts, Am J Physiol Heart Cric Physiol, 272, H1656, 10.1152/ajpheart.1997.272.4.H1656
Krause, 1995, Adenosine triphosphate-dependent K+ currents activated by metabolic inhibition in rat ventricular myocytes differ from those elicited by the channel opener rilmakalim, Pflugers Arch, 429, 625, 10.1007/BF00373983
Krumenacker, 1992, Clinical profile of nicorandil — an overview of its hemodynamic properties and therapeutic efficacy, J Cardiovasc Pharmacol, 20, S93
Kubota, 1993, Role of ATP-sensitive K+ channel on ECG ST segment elevation during a bout of myocardial ischemia. A study on epicardial mapping in dogs, Circulation, 88, 1845, 10.1161/01.CIR.88.4.1845
Lepran, 1996, ATP-sensitive potassium channel modulators: both pinacidil and glibenclamide produce antiarrhythmic activity during acute myocardial infarction in conscious rats, J Pharmacol ExpTher, 277, 1215
Li, 2000, Molecular basis of electrocardiographic ST-segment elevation, Circ Res, 87, 837, 10.1161/01.RES.87.10.837
Link, 1999, Selective activation of the K+ATP channel is a mechanism by which sudden death is produced by low-energy chest-wall impact (Commotio cordis), Circulation, 100, 413, 10.1161/01.CIR.100.4.413
Liss, 2001, Molecular physiology of neuronal K-ATP channels, Mol Membr Biol, 18, 117, 10.1080/09687680110047373
Liu, 1998, Mitochondrial ATP-dependent potassium channels: novel effectors of cardioprotection?, Circulation, 97, 2463, 10.1161/01.CIR.97.24.2463
Liu, 2001, Pharmacological comparison of native mitochondrial KATP channels with molecularly defined surface KATP channels, Mol Pharmacol, 59, 225, 10.1124/mol.59.2.225
Lomuscio, 1996, Influence of oral antidiabetic treatment on electrocardiac alterations induced by myocardial infarction, Diabetes Res Clin Pract, 31, S21, 10.1016/0168-8227(96)01226-0
Lomuscio, 1994, Effects of glibenclamide on ventricular fibrillation in non-insulin-dependent diabetics with acute myocardial infarction, Coron Artery Dis, 5, 767
MacKenzie, 1993, Differential class III and glibenclamide effects on action potential duration in guinea-pig papillary muscle during normoxia and hypoxia/ischaemia, Br J Pharmacol, 110, 531, 10.1111/j.1476-5381.1993.tb13843.x
Manning-Fox, 2002, Cardioselectivity of the sulphonylurea HMR 1098: studies on native and recombinant cardiac and pancreatic K-ATP channels, Br J Pharmacol, 135, 480, 10.1038/sj.bjp.0704455
Mitani, 1992, Role of Na-activated K channel, Na–K–Cl cotransport, Na–K pump and [K]e changes during ischemia in the rat heart, Am J Physiol Heart Cric Physiol, 263, H333, 10.1152/ajpheart.1992.263.2.H333
Mitani, 1991, Effects of glibenclamide and nicorandil on cardiac function during ischemia and reperfusion in isolated perfused rat hearts, Am J Physiol Heart Circ Physiol, 261, H1864, 10.1152/ajpheart.1991.261.6.H1864
Nakaya, 1991, Effects of ATP-sensitive K+ channel blockers on the action potential shortening in hypoxic and ischaemic myocardium, Br J Pharmacol, 103, 1019, 10.1111/j.1476-5381.1991.tb12294.x
Nattel, 2000, Class III drugs: amiodarone, bertylium, ibutilide, and sotalol, 921
Nichols, 2006, KATP channels as molecular sensors of cellular metabolism, Nature, 440, 470, 10.1038/nature04711
Nichols, 1990, The regulation of ATP-sensitive K+ channel activity in intact and permeabilized rat ventricular myocytes, J Physiol (Lond), 423, 91, 10.1113/jphysiol.1990.sp018013
Nichols, 1991, Adenosine triphosphate-sensitive potassium channels in the cardiovascular system, Am J Physiol Heart Circ Physiol, 261, H1675, 10.1152/ajpheart.1991.261.6.H1675
Nichols, 1991, ATP-sensitive potassium channel modulation of the guinea pig ventricular action potential and contraction, Circ Res, 68, 280, 10.1161/01.RES.68.1.280
Nichols, 1996, Adenosine diphosphate as intracellular regulator of insulin section, Science, 272, 1785, 10.1126/science.272.5269.1785
Noma, 1983, ATP-regulated K+ channels in cardiac muscle, Nature, 305, 147, 10.1038/305147a0
Olschewski, 1996, ATP-dependent potassium channel in rat cardiomyocytes is blocked by lidocaine. Possible impact on the antiarrhythmic action of lidocaine, Circulation, 93, 656, 10.1161/01.CIR.93.4.656
Opie, 1979, Biochemical aspects of arrhythmogenesis, Am J Cardiol, 43, 131, 10.1016/0002-9149(79)90055-9
Opthof, 2007, Dispersion of repolarization in canine ventricle and electrocardiographic T wave: Tp–e interval does not reflect transmural dispersion, Heart Rhythm, 4, 341, 10.1016/j.hrthm.2006.11.022
O'Rourke, 2000, Myocardial KATP channels in preconditioning, Circ Res, 87, 845, 10.1161/01.RES.87.10.845
Pasnani, 1992, Differential effects of glyburide on premature beats and ventricular tachycardia in an isolated tissue model of ischemia and reperfusion, J Pharmacol Exp Ther, 262, 1076
Patel, 1999, Cardioprotection by opening of the KATP channel in unstable angina, Eur Heart J., 20, 51, 10.1053/euhj.1998.1354
Pogatsa, 1988, The effect of various hypoglycaemic sulphonylureas on the cardiotoxicity of glycosides and arrhythmogenic activity due to myocardial ischaemia, Acta Physiol Hung, 71, 243
Rau, 1977, Potassium exchange and mechanical performance in anoxic mammalian myocardium, Am J Physiol Heart Circ Physiol, 232, H85, 10.1152/ajpheart.1977.232.1.H85
Remme, 2000, KATP channel opener, myocardial ischemia and arrhythmias — should the electrophysiologist worry?, Cardiovasc Drug Ther, 14, 17, 10.1023/A:1007882819423
Rees, 1995, Pharmacological analysis in rat of the role of the ATP-sensitive potassium channels as a potential target fro antifibrillatory intervention in acute myocardial-ischemia, J Cardiovasc Pharmacol, 26, 280, 10.1097/00005344-199508000-00014
Rees, 1993, Combined administration of an Ik(ATP) activator and Ito blocker increases coronary blood flow independently of effects on heart rate, QT interval, and ischaemai-induced ventricular fibrillation in rats, J Cardiovasc Pharmacol, 22, 343, 10.1097/00005344-199309000-00001
Reimann, 2001, Effects of mitiglinide (S 21403) on Kir6.2/SUR1, Kir6.2/SUR2A and Kir6.2/SUR2B types of ATP-sensitive potassium channel, Br J Pharmacol, 132, 1542, 10.1038/sj.bjp.0703962
Rovetto, 1973, Comparison of the effects of anoxia and whole heart ischemia on carbohydrate utilization in isolated working rat hearts, Circ Res, 32, 699, 10.1161/01.RES.32.6.699
Rubart, 2005, Mechanism of sudden cardiac death, J Clin Invest, 115, 2305, 10.1172/JCI26381
Ruiz-Petrich, 1992, Effects of K+ channel blockers on the action potential of hypoxic rabbit myocardium, Br J Pharmacol, 106, 924, 10.1111/j.1476-5381.1992.tb14436.x
Sager, 1999, New advances in class III antiarrhythmic drug therapy, Curr Opin Cardiol, 14, 15, 10.1097/00001573-199901000-00004
Saito, 2005, Role of ATP-sesntive K+ cahnnels in electrophysiological alterations during myocardial ischemia: a study using Kir6.2-null mice, Am J Physiol Heart Circ Physiol, 288, H352, 10.1152/ajpheart.00695.2004
Sato, 1999, Signaling in late preconditioning: involvement of mitochondrial KATP channels, Circ Res, 85, 1113, 10.1161/01.RES.85.12.1113
Sato, 2000, The role of mitochondrial KATP channels in cardioprotection, Bas Res Cardiol, 95, 285, 10.1007/s003950070047
Sato, 2000, Selective pharmacological agents implicate mitochondrial but not sarcolemmal KATP channels in ischemic cardioprotection, Circulation, 101, 2418, 10.1161/01.CIR.101.20.2418
Sato, 2003, Amiodarone inhibits sarcolemmal but not mitchondrial K-ATP channels in guinea pig ventricular cells, J Pharmacol Exp Therap, 307, 955, 10.1124/jpet.103.055863
Sato, 2006, Bepridil, an antiarrhythmic drug, opens mitochondrial KATP channels, blocks sarcolemmal KATP channels, and confers cardioprotection, J Pharmacol Exp Therap, 316, 182, 10.1124/jpet.105.094029
Schnitzler, 2000, ATP-sensitive potassium channels in capillaries isolated from guinea-pig heart, J Physiol (Lond), 525, 307, 10.1111/j.1469-7793.2000.t01-1-00307.x
Shieh, R. C., Goldhaber, J. I., Stuart, J. S., & Weiss, J. N. (1994). Lactate transport in mammalian ventricle: general properties and relation to K+ efflux. Circ Res 74, 829–838.
Shine, 1977, 42K exchange during myocardial ischemia, Am J Physiol Heart Circ Physiol, 232, H564, 10.1152/ajpheart.1977.232.6.H564
Smallwood, 1990, Modification by glibenclamide of the electrophysiological consequences of myocardial ischaemia in dogs and rabbits, Naunyn Schmiedebergs Arch Pharmacol, 342, 214, 10.1007/BF00166967
Suzuki, 2001, Functional roles of cardiac and vascular ATP-sensitive potassium channels clarified by Kir6.2-knockout mice, Circ Res, 88, 570, 10.1161/01.RES.88.6.570
Torp-Pedersen, 1997, Classification of sudden and arrhythmic death, PACE, 20, 2545, 10.1111/j.1540-8159.1997.tb06103.x
Tosaki, 1995, Diabetes and ATP-sensitive potassium channel openers and blockers in isolated ischemic/reperfused hearts, J Pharmacol Exp Ther, 275, 1115
Trube, 1984, Inward-rectifying channels in isolated patches of the heart cell membrane: ATP-dependence and comparison with cell-attached patches, Pfugers Arch, 401, 178, 10.1007/BF00583879
Tweedie, 1993, Glibenclamide, but not class III drugs, prevents ischaemic shortening of the refractory period in guinea-pig hearts, Eur J Pharmacol, 240, 251, 10.1016/0014-2999(93)90906-X
Uchida, 1999, Mechanism of acceleration of functional reentry in the ventricle: effects of ATP-sensitive potassium channel opener, Circulation, 99, 704, 10.1161/01.CIR.99.5.704
Vajda, 2007, Selective cardiac plasma-membrane KATP channel inhibition is defibrillatory and improves survival during acute myocardial ischemia and reperfusion, Eur J Pharmacol, 577, 115, 10.1016/j.ejphar.2007.08.016
Vanheel, 1992, Influence of KATP channel modulation on net potassium efflux from ischaemic mammalian cardiac tissue, Cardiovasc Res, 26, 1030, 10.1093/cvr/26.11.1030
Venkatesh, 1991, Sulfonylureas, ATP-sensitive K+ channels, and cellular K+ loss during hypoxia, ischemia, and metabolic inhibition in mammalian ventricle, Circ Res, 69, 623, 10.1161/01.RES.69.3.623
Venkatesh, 1992, Activation of ATP-sensitive K+ channels by cromakalim: effects on cellular K+ loss and cardiac function in ischemic and reperfused mammalian ventricle, Circ Res, 71, 1324, 10.1161/01.RES.71.6.1324
Waldo, 1996, Effect of d-sotalol on mortality in patients with left ventricular dysfunction after recent and remote myocardial infarction, Lancet, 348, 7, 10.1016/S0140-6736(96)02149-6
Wang, 2001, Phospholipid metabolite 1-palmitoyl-lysophosphatidylcholine enhances human ether-a-go-go-related gene (HERG) K+ channel function, Circulation, 104, 2645, 10.1161/hc4701.100513
Weiss, 1992, ATP-sensitive K+ channels and cellular K+ loss in hypoxic and ischaemic mammalian ventricle, J Physiol (Lond), 447, 649, 10.1113/jphysiol.1992.sp019022
Weyermann, 2004, Inhibitors of ATP-sensitive potassium channels in guinea pig isolated ischemic hearts, Naunyn Schmiedebergs Arch Pharmacol, 369, 374, 10.1007/s00210-004-0882-0
Wilde, 1993, Role of ATP-sensitive K+ channel current in ischemic arrhythmias, Cardiovasc Drugs Ther, 7, 521, 10.1007/BF00877617
Wilde, 1998, ATP and the role of IKATP during acute myocardial ischaemia: controversies revive, Cardiovasc Res, 35, 181
Wilde, 1995, Myocardial potassium loss and cell depolarization in ischaemia and hypoxia, Cardiovasc Res., 29, 1, 10.1016/0008-6363(96)88539-7
Wilde, 1990, Potassium accumulation in the globally ischemic mammalian heart. A role for the ATP-sensitive potassium channel, Circ Res, 67, 835, 10.1161/01.RES.67.4.835
Wirth, 1999, ATP-sensitive potassium channel blocker HMR 1883 reduces mortality and ischemia-associated electrocardiographic changes in pigs with coronary occlusion, J Pharmacol ExpTher, 291, 474
Wirth, 1999, HMR 1883, a cardioselective K(ATP) channel blocker, inhibits ischaemia- and reperfusion-induced ventricular fibrillation in rats, Naunyn Schmiedebergs Arch Pharmacol, 360, 295, 10.1007/s002109900084
Wirth, 2000, KATP channel blocker HMR 1883 reduces monophasic action potential shortening during coronary ischemia in anesthetised pigs, Naunyn Schmiedebergs Arch Pharmacol, 361, 155, 10.1007/s002109900166
Wit, 1989, Electrophysiological mechanisms of ventricular arrhythmias resulting from myocardial ischemia and infarction, Physiol Rev, 69, 1049, 10.1152/physrev.1989.69.4.1049
Wolk, 1999, Relevance of inter- and intraventricular electrical dispersion to arrhythmogenesis in normal and ischaemic rabbit myocardium: a study with cromakalim, 5-hydroxydecanoate and glibenclamide, J Cardiovasc Pharmacol, 33, 323, 10.1097/00005344-199902000-00022
Wolleben, 1989, Influence of ATP-sensitive potassium channel modulators on ischemia-induced fibrillation in isolated rat hearts, J Mol Cell Cardiol, 21, 783, 10.1016/0022-2828(89)90717-7
Yan, 1998, Cellular basis for the normal T wave and the electrocardiographic manifestations of the long-QT syndrome, Circulation, 98, 1928, 10.1161/01.CIR.98.18.1928
Yan, 1993, Dissociation between cellular K+ loss, reduction in repolarization time, and tissue ATP levels during myocardial hypoxia and ischemia, Circ Res, 72, 560, 10.1161/01.RES.72.3.560
Yazar, 2002, Effects of glibenclamide, metaformin and insulin on the incidence and latency of death by ouabian-induced arrhythmias, Pharmacol Res, 45, 183, 10.1006/phrs.2001.0944
Zhang, 1991, Effects of glibenclamide and tolbutamine on ischemia-induced and ouabain-induced arrhythmias and membrane potentials of ventricular myocardium from rat and guinea-pig, Acta Pharmcol Sinica, 12, 398
Zheng, 2001, Sudden cardiac death in the United States, 1989 to 1998, Circulation, 104, 2158, 10.1161/hc4301.098254
Zhu, 2003, Effect of sarcolemmal K-ATP blocker HMR 1098 on arrhythmias induced by programmed electrical stimulation in canine old myocardial infarction model: comparison with glibenclamide, J Pharmacol Sci, 93, 106, 10.1254/jphs.93.106
Zipes, 1998, Sudden cardiac death, Circulation, 98, 2334, 10.1161/01.CIR.98.21.2334