Drug modulation of GABAA-mediated transmission

Tobin, 1991, Molecular biological approaches to the synthesis and action of GABA, Semin Neurosci, 3, 183, 10.1016/1044-5765(91)90015-G 1986 Ticku, 1990, Alcohol and GABA-benzodiazepine receptor function, Ann Med, 22, 241, 10.3109/07853899009148934 Olsen, 1983, [3H]Bicuculline methchloride binding to low-affinity-γ-aminobutyric acid receptor sites, J Neurochem, 41, 1653, 10.1111/j.1471-4159.1983.tb00877.x Maksay, 1984, Diazotization and thiocyanate differentiate agonists from antagonists for the high- and low-affinity receptor of γ-aminobutyric acid, J Neurochem, 43, 261, 10.1111/j.1471-4159.1984.tb06705.x Johnston, 1991, GABAA antagonists, Semin Neurosci, 3, 205, 10.1016/1044-5765(91)90017-I Takeuchi, 1969, A study of the action of picrotoxin on the inhibitory neuromuscular junction of the crayfish, J Physiol, 205, 377, 10.1113/jphysiol.1969.sp008972 Lunt, 1991, GABA and GABA receptors in invertebrates, Semin Neurosci, 3, 251, 10.1016/1044-5765(91)90022-G Simmonds, 1980, Evidence that bicuculline and picrotoxin act at separate sites to antagonize γ-aminobutyric acid in rat cuneate nucleus, Neuropharmacol, 78, 353 Ticku, 1978, Binding of [3H]α-dihydropicrotoxinin, a γ-aminobutyric acid synaptic antagonist, to rat brain, Mol Pharmacol, 14, 391 Olsen, 1978, Dihydropicrotoxinin binding to crayfish muscle sites possibly related to γ-aminobutyric acid receptor-ionophores, Mol Pharmacol, 14, 381 Ticku, 1980, [3H]α-Dihydropicrotoxinin binds to primary neuronal but not glial cells, Eur J Pharmacol, 65, 135, 10.1016/0014-2999(80)90225-3 Napias, 1980, GABA and picrotoxin binding in cloned nerve cells, Nature, 283, 298, 10.1038/283298a0 Ticku, 1979, Cage convulsants inhibit picrotoxinin binding, Neuropharmacology, 18, 315, 10.1016/0028-3908(79)90132-1 Bowery, 1976, GABA antagonism as possible basis for convulsant action of series of bicyclophosphate esters, Br J Pharmacol, 58, 435 Casida, 1976, Structure-toxicity relationship of 2,6,7-trioxyabicyclo (2.2.2)-oxtane and related compounds, Toxicol Appl Pharmacol, 36, 261, 10.1016/0041-008X(76)90006-5 Squires, 1983, [35S]t-butylbicyclophosphorothionate binds with high affinity to brain specific sites coupled to γ-aminobutyric acidA and ion recognition sites, Mol Pharmacol, 23, 326 Ramanjaneyulu, 1984, Binding characteristics and interaction of depressant drugs with [35S]t-butylbicyclophosphorothionate, a ligand that binds to the picrotoxinin site, J Neurochem, 42, 221, 10.1111/j.1471-4159.1984.tb09721.x Ticku, 1986, Convulsant binding sites on the benzodiazepine/GABA receptor, 195 Ramanjaneyulu, 1984, Interaction of pentylenetetrazol and tetrazole analogues with the picrotoxin site of the benzodiazepine-GABA receptor-ionophore complex, Eur J Pharmacol, 98, 337, 10.1016/0014-2999(84)90282-6 Klunk, 1983, Computer-assisted modelling of picrotoxinin and γ-butyrolactone receptor site, Mol Pharmacol, 23, 511 Levine, 1986, Alkyl-substituted thiolothiono, and dithio-γ-butyrolactones: new classes of convulsant and anticonvulsant agents, J Med Chem, 29, 1996, 10.1021/jm00160a032 Holland, 1990, Physiological regulation of the picrotoxin receptor by γ-butyrolactones and γ-thiobutyrolactones in cultured hippocampal neurons, J Neurosci, 10, 1719, 10.1523/JNEUROSCI.10-06-01719.1990 Maksay, 1985, Dissociation of [35S]t-butylbicyclophosphorothionate binding differentiates convulsant and depressant drugs that modulate GABAergic transmission, J Neurochem, 44, 480, 10.1111/j.1471-4159.1985.tb05439.x Lawrence, 1984, Interaction of lindane, toxaphene and cyclodienes with brain specific t-butylbicyclophosphorothionate receptor, Life Sci, 35, 171, 10.1016/0024-3205(84)90136-X Grant, 1987, Cyclodiene insecticides inhibit GABAA receptor regulated chloride transport, Toxicol Appl Pharmacol, 88, 313, 10.1016/0041-008X(87)90206-7 Ogata, 1988, Lindane but not deltamethrin blocks a component of GABA-activated chloride channels, FASEB J, 2, 2895, 10.1096/fasebj.2.13.2458984 Ticku, 1983, Convulsant/depressant site of action at the allosteric benzodiazepine-GABA receptorionophore complex, Life Sci, 33, 2363, 10.1016/0024-3205(83)90630-6 Macdonald, 1991, Biophysical properties and regulation of GABAA receptor channels, Semin Neurosci, 3, 219, 10.1016/1044-5765(91)90019-K Mehta, 1988, Interactions of pentobarbital and phenobarbital with GABAergic drugs against chemoconvulsants in rats, Pharmacol Biochem Behav, 30, 995, 10.1016/0091-3057(88)90131-1 Trifiletti, 1985, Barbiturate recognition site on the GABA/benzodiazepine receptor complex is distinct from the picrotoxinin/TBPS recognition site, Eur J Pharmacol, 106, 441, 10.1016/0014-2999(84)90737-4 Blair, 1988, Single subunits of the GABAA receptor form ion channels with properties of the native receptor, Science, 242, 577, 10.1126/science.2845583 Majewska, 1986, Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor, Science, 232, 1004, 10.1126/science.2422758 Kirkness, 1989, Steroid modulation reveals further complexity of GABAA receptors, Trends Pharmacol Sci, 10, 6, 10.1016/0165-6147(89)90091-6 Belelli, 1990, Anticonvulsant steroids and the GABA/benzodiazepine receptor-chloride ionophore complex, Neurosci Biobehav Reviews, 14, 315, 10.1016/S0149-7634(05)80041-7 Simmonds, 1991, Modulation of the GABAA receptor by steroids, Semin Neurosci, 3, 231, 10.1016/1044-5765(91)90020-O Majewska, 1989, Pregnancy induced alterations of GABAA receptor sensitivity in maternal brain: an antecedent of post-partum ‘blues’?, Brain Res, 482, 397, 10.1016/0006-8993(89)91208-0 Ticku, 1988, Molecular interactions of ethanol with GABAergic system and potential of RO15–4513 as an ethanol antagonist, Pharmacol Biochem Behav, 30, 501, 10.1016/0091-3057(88)90487-X Mehta, 1988, Ethanol potentiation of GABAergic transmission in cultured spinal cord neurons involves γ-aminobutyric acidA-gated chloride channels, J Pharmacol Exp Ther, 246, 558 Suzdak, 1986, A selective imidazobenzodiazepine antagonist of ethanol in the rat, Science, 234, 1243, 10.1126/science.3022383 Allan, 1986, Gamma-aminobutyric acid and alcohol actions: neurochemical studies in long sleep and short sleep mice, Life Sci, 39, 2005, 10.1016/0024-3205(86)90324-3 Morrow, 1988, Chronic ethanol administration alters γ-aminobutyric acid, pentobarbital and ethanol-mediated 36Cl uptake in cerebral cortical synaptoneurosomes, J Pharmacol Exp Ther, 246, 158 Morrow, 1990, Chronic ethanol and pentobarbital administration in the rat: effects on GABAA receptor function and expression in brain, Alcohol, 7, 237, 10.1016/0741-8329(90)90012-2 Mhatre, 1991, Chronic ethanol administration alters GABA receptor gene expression, Alcohol Clin Exp Res Montpied, 1991, Chronic ethanol administration decreases GABAA receptor α subunit mRNAs in the rat cerebral cortex, Mol Pharmacol Ludden, 1990, A cerebellar GABAA receptor selective for a behavioral alcohol antagonist, Nature, 346, 648, 10.1038/346648a0 Ticku, 1991, Chronic ethanol administration induces changes in GABAA receptor gene expression, Neurosci Abstr Mehta, 1986, Comparison of anticonvulsant effect of pentobarbital and phenobarbital against seizures induced by maximal electroshock and picrotoxin in rats, Pharmacol Biochem Behav, 25, 1059, 10.1016/0091-3057(86)90085-7