Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ

Nature - Tập 429 Số 6993 - Trang 771-776 - 2004
Frédéric Picard1, Martin V. Kurtev2, Namjin Chung2, Acharawan Topark‐Ngarm3, Thanaset Senawong3, Kenneth Ndebele2,4, Mark Leid3, Michael W. McBurney5, Leonard Guarente2
1Department of Biology Massachusetts Institute of Technology Cambridge, Massachusetts 02139 USA
2Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
3Laboratory of Molecular Pharmacology, Department of Pharmaceutical Sciences, College of Pharmacy and Environmental Health Science Center, Oregon State University, Corvallis, USA
4Graduate Program in Basic and Applied Biology, ICBAS, University of Porto, Portugal
5Ottawa Regional Cancer Centre and Department of Medicine, University of Ottawa, Ontario, Canada

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