Inhaled Insulin: An Innovation with the Potential to Transform the Management of Type 1 and Type 2 Diabetes

American Diabetes Association 2007, Standards of Medical Care in Diabetes–2007, Diabetes Care, 30, S4 National Diabetes Statistics Daily, 2005, Early insulin: an important therapeutic strategy, Diabetes Care, 281, 220, 10.2337/diacare.28.1.220 Laube, 2001, Treating diabetes with aerosolized insulin, Chest, 120, 99S, 10.1378/chest.120.3_suppl.99S Hite, 2006, Exuberance over Exubera, Clin Diabetes, 24, 110, 10.2337/diaclin.24.3.110 Kumar, 2006, Novel delivery of technologies for protein and peptide therapeutics, Curr Pharm Biotechnol, 7, 261, 10.2174/138920106777950852 Trubo, 2005, Interest in inhaled insulin grows, JAMA, 294, 1195, 10.1001/jama.294.10.1195 Rosenstock, 2006, Inhaled insulin improves glycemic control when substituted for or added to oral combination therapy in type 2 diabetes, Ann Intern Med, 143, 549, 10.7326/0003-4819-143-8-200510180-00005 Abrahamson Peyrot, 2005, (2005) Resistance to insulin therapy among patients and providers, Diabetes Care, 28, 2673, 10.2337/diacare.28.11.2673 Barnett, 2004, Exubera inhaled insulin: a review, Int J Clin Pract, 58, 394, 10.1111/j.1368-5031.2004.00178.x Hollander, 2004, Efficacy and safety of inhaled insulin compared with subcutaneous insulin therapy in patients with type 2 diabetes: results of a 6-month, randomized, comparative trial, Diabetes Care, 27, 2356, 10.2337/diacare.27.10.2356 Rave, 2005, Dose response of inhaled dry-powder insulin and dose equivalence to subcutaneous insulin lispro, Diabetes Care, 28, 2400, 10.2337/diacare.28.10.2400 Diabetes Research Institute () Skyler, 2005, Inhaled Insulin Phase III Type I Diabetes Study Group. Use of inhaled insulin in a basal/bolus insulin regimen in type 1 diabetic subjects: a 6-month, randomized, comparative trial, Diabetes Care, 28, 1630, 10.2337/diacare.28.7.1630 DeFronzo, 2005, Exubera Phase III Study Group. Efficacy of inhaled insulin in patients with type 2 diabetes not controlled with diet and exercise: a 12-week, randomized, comparative trial, Diabetes Care, 28, 1922, 10.2337/diacare.28.8.1922 Fabbri, 2006, Pulmonary safety of inhaled insulins: a review of the current data, Curr Med Res Opin, 22, 21, 10.1185/030079906X132712 2007