The Hodgkin and Reed/Sternberg cell

Bargou, 1997, Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells, Journal of Clinical Investigation, 100, 2961, 10.1172/JCI119849

Bräuninger, 1999, Identification of common germinal-center B-cell precursors in two patients with both Hodgkin's disease and non-Hodgkin's lymphoma, The New England Journal of Medicine, 340, 1239, 10.1056/NEJM199904223401604

Cabannes, 1999, Mutations in the IκBα gene in Hodgkin's disease suggest a tumour suppressor role for IκBα, Oncogene, 18, 3063, 10.1038/sj.onc.1202893

Emmerich, 1999, Overexpression of I kappa B alpha without inhibition of NF-kappaB activity and mutations in the I kappa B alpha gene in Reed–Sternberg cells, Blood, 94, 3129, 10.1182/blood.V94.9.3129

Hodgkin, 1832, On some morbid appearances of the absorbent glands and spleen, Medical Chirurgical Transactions, 17, 68, 10.1177/095952873201700106

Horie, 2002, Ligand-independent signaling by overexpressed CD30 drives NF-kappaB activation in Hodgkin–Reed–Sternberg cells, Oncogene, 21, 2493, 10.1038/sj.onc.1205337

Jarrett, 1999, Epstein-Barr virus and other candidate viruses in the pathogenesis of Hodgkin's disease, Seminars in Hematology, 36, 260

Joos, 2002, Classical Hodgkin lymphoma is characterized by recurrent copy number gains of the short arm of chromosome 2, Blood, 99, 1381, 10.1182/blood.V99.4.1381

Jundt, 2001, Activated notch 1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma, Blood, 99, 3398, 10.1182/blood.V99.9.3398

Jungnickel, 2000, Clonal deleterious mutations in the iκBα gene in the malignant cells in Hodgkin's disease, Journal of Experimental Medicine, 191, 395, 10.1084/jem.191.2.395

Kanzler, 1996, Hodgkin and Reed–Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells, Journal of Experimental Medicine, 184, 1495, 10.1084/jem.184.4.1495

Kanzler, 2000, Hodgkin and Reed–Sternberg-like cells in B-cell chronic lymphocytic leukemia represent the outgrowth of single germinal-center B-cell-derived clones: potential precursors of Hodgkin and Reed–Sternberg cells in Hodgkin's disease, Blood, 95, 1023, 10.1182/blood.V95.3.1023.003k07_1023_1031

Kapp, 1999, Interleukin 13 is secreted by and stimulates the growth of Hodgkin and Reed–Sternberg cells, Journal of Experimental Medicine, 189, 1939, 10.1084/jem.189.12.1939

Kashkar, 2003, XIAP-mediated caspase inhibition in Hodgkin's lymphoma-derived B cells, Journal of Experimental Medicine, 198, 341, 10.1084/jem.20021279

Küppers, 2002, Molecular biology of Hodgkin's lymphoma, Advances in Cancer Research, 44, 277, 10.1016/S0065-230X(02)84009-X

Küppers, 1994, Hodgkin disease: Hodgkin and Reed–Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of development, 10962

Kurth, 2000, EBV-infected B cells in infectious mononucleosis: viral strategies for spreading in the B cell compartment and establishing latency, Immunity, 13, 485, 10.1016/S1074-7613(00)00048-0

Marafioti, 2000, Hodgkin and Reed–Sternberg cells represent an expansion of a single clone originating from a germinal center B-cell with functional immunoglobulin gene rearrangements but defective immunoglobulin transcription, Blood, 95, 1443, 10.1182/blood.V95.4.1443.004k55_1443_1450

Mathas, 2004, c-FLIP mediates resistance of Hodgkin/Reed–Sternberg cells to death receptor-induced apoptosis, Journal of Experimental Medicine, 199, 1041, 10.1084/jem.20031080

Müschen, 2000, Rare occurrence of classical Hodgkin's disease as a T cell lymphoma, Journal of Experimental Medicine, 191, 387, 10.1084/jem.191.2.387

Re, 2000, Cultivated H-RS cells are resistant to CD95L-mediated apoptosis despite expression of wild-type CD95, Experimental Hematology, 28, 31, 10.1016/S0301-472X(99)00125-3

Re, 2001, Oct-2 and Bob-1 deficiency in Hodgkin and Reed–Sternberg cells, Cancer Research, 61, 2080

Reed, 1902, On the pathological changes in Hodgkin's disease with special reference to its relation to tuberculosis, John Hopkins Hospital Reports, 10, 133

Schwering, 2003, Loss of the B-lineage-specific gene expression program in Hodgkin and Reed–Sternberg cells of Hodgkin lymphoma, Blood, 101, 1505, 10.1182/blood-2002-03-0839

Seitz, 2000, Detection of clonal T-cell receptor gamma-chain gene rearrangements in Reed–Sternberg cells of classic Hodgkin disease, Blood, 95, 3020, 10.1182/blood.V95.10.3020

Spina, 1996, Growth vs. DNA strand breaks in Hodgkin's disease: impaired proliferative ability of Hodgkin and Reed–Sternberg cells, International Journal of Cancer, 66, 179, 10.1002/(SICI)1097-0215(19960410)66:2<179::AID-IJC7>3.0.CO;2-#

Stein, 2001, Classical Hodgkin lymphoma, 244

Stein, 2001, Down-regulation of BOB.1/OBF.1 and Oct2 in classical Hodgkin disease but not in lymphocyte predominant Hodgkin disease correlates with immunoglobulin transcription, Blood, 97, 496, 10.1182/blood.V97.2.496

Sternberg, 1898, Über eine eigenartige unter dem Bilde der Pseudoleukämie verlaufende Tuberkolose des lymphatischen Apparates, Zeitschrift für Heilkunde, 19, 21

van den Berg, 1999, High expression of the CC chemokine TARC in Reed–Sternberg cells. A possible explanation for the characteristic T-cell infiltration Hodgkin's lymphoma, American Journal of Pathology, 154, 1685, 10.1016/S0002-9440(10)65424-7

Weiss, 1999, Pathology of classical Hodgkin's disease, 101