Radiotherapy Dose–Volume Effects on Salivary Gland Function

Dawes, 1973, The contribution of oral minor mucous gland secretions to the volume of whole saliva in man, Arch Oral Biol, 18, 337, 10.1016/0003-9969(73)90156-8 Buus, 2006, Individual radiation response of parotid glands investigated by dynamic 11C-methionine PET, Radiother Oncol, 78, 262, 10.1016/j.radonc.2006.02.013 Astreinidou, 2007, 3D MR sialography as a tool to investigate radiation-induced xerostomia: Feasibility study, Int J Radiat Oncol Biol Phys, 68, 1310, 10.1016/j.ijrobp.2007.01.062 Chao, 2001, A prospective study of salivary function sparing in patients with head-and-neck cancers receiving intensity-modulated or three-dimensional radiation therapy: Initial results, Int J Radiat Oncol Biol Phys, 49, 907, 10.1016/S0360-3016(00)01441-3 Meirovitz, 2006, Grading xerostomia by physicians or by patients after intensity-modulated radiotherapy of head-and-neck cancer, Int J Radiat Oncol Biol Phys, 66, 445, 10.1016/j.ijrobp.2006.05.002 Blanco, 2005, Dose-volume modeling of salivary function in patients with head-and-neck cancer receiving radiotherapy, Int J Radiat Oncol Biol Phys, 62, 1055, 10.1016/j.ijrobp.2004.12.076 Eisbruch, 2001, Xerostomia and its predictors following parotid-sparing irradiation of head-and-neck cancer, Int J Radiat Oncol Biol Phys, 50, 695, 10.1016/S0360-3016(01)01512-7 Maes, 2002, Preservation of parotid function with uncomplicated conformal radiotherapy, Radiother Oncol, 63, 203, 10.1016/S0167-8140(02)00013-0 Li, 2007, The impact of dose on parotid salivary recovery in head and neck cancer patients treated with radiation therapy, Int J Radiat Oncol Biol Phys, 67, 660, 10.1016/j.ijrobp.2006.09.021 Braam, 2007, Quality of life and salivary output in patients with head-and-neck cancer five years after radiotherapy, Radiat Oncol, 2, 3, 10.1186/1748-717X-2-3 Robar, 2007, Spatial and dosimetric variability of organs at risk in head-and-neck intensity-modulated radiotherapy, Int J Radiat Oncol Biol Phys, 68, 1121, 10.1016/j.ijrobp.2007.01.030 Saarilahti, 2006, Sparing of the submandibular glands by intensity modulated radiotherapy in the treatment of head and neck cancer, Radiother Oncol, 78, 270, 10.1016/j.radonc.2006.02.017 Portaluri, 2006, Three-dimensional conformal radiotherapy for locally advanced (stage II and worse) head-and-neck cancer: Dosimetric and clinical evaluation, Int J Radiat Oncol Biol Phys, 66, 1036, 10.1016/j.ijrobp.2006.03.014 Roesink, 2001, Quantitative dose–volume response analysis of changes in parotid gland function after radiotherapy in the head-and-neck region, Int J Radiat Oncol Biol Phys, 51, 938, 10.1016/S0360-3016(01)01717-5 Roesink, 2004, Scintigraphic assessment of early and late parotid gland function after radiotherapy for head-and-neck cancer: A prospective study of dose–volume response relationships, Int J Radiat Oncol Biol Phys, 58, 1451, 10.1016/j.ijrobp.2003.09.021 Bussels, 2004, Dose–response relationships within the parotid gland after radiotherapy for head and neck cancer, Radiother Oncol, 73, 297, 10.1016/j.radonc.2004.09.015 Eisbruch, 1999, Dose, volume, and function relationships in parotid salivary glands following conformal and intensity-modulated irradiation of head and neck cancer, Int J Radiat Oncol Biol Phys, 45, 577, 10.1016/S0360-3016(99)00247-3 Munter, 2007, Evaluation of salivary gland function after treatment of head-and-neck tumors with intensity-modulated radiotherapy by quantitative pertechnetate scintigraphy, Int J Radiat Oncol Biol Phys, 58, 175, 10.1016/S0360-3016(03)01437-8 Munter, 2007, Changes in salivary gland function after radiotherapy of head and neck tumors measured by quantitative pertechnetate scintigraphy: Comparison of intensity-modulated radiotherapy and conventional radiation therapy with and without amifostine, Int J Radiat Oncol Biol Phys, 67, 651, 10.1016/j.ijrobp.2006.09.035 Rudat, 2008, The effect of amifostine or IMRT to preserve the parotid function after radiotherapy of the head and neck region measured by quantitative salivary gland scintigraphy, Radiother Oncol, 89, 71, 10.1016/j.radonc.2008.07.016 Deasy, 2001, Uncertainties in model-based outcome predictions for treatment planning, Int J Radiat Oncol Biol, 51, 1389, 10.1016/S0360-3016(01)02659-1 Franzen, 1992, Fractionated irradiation and early changes in noradrenaline induced potassium efflux (86Rb+) in rat parotid gland, Acta Oncol, 31, 359, 10.3109/02841869209108186 Leslie, 1994, The early changes in salivary gland function during and after radiotherapy for head and neck cancer, Radiother Oncol, 30, 26, 10.1016/0167-8140(94)90006-X Price, 1995, Effects of continuous hyperfractionated accelerated and conventionally fractionated radiotherapy on the parotid and submandibular salivary glands of rhesus monkeys, Radiother Oncol, 34, 39, 10.1016/0167-8140(94)01491-K Lombaert, 2008, Rescue of salivary gland function after stem cell transplantation in irradiated glands, PLoS ONE, 3, e2063, 10.1371/journal.pone.0002063 Konings, 2005, Volume effects and region-dependent radiosensitivity of the parotid gland, Int J Radiat Oncol Biol Phys, 62, 1090, 10.1016/j.ijrobp.2004.12.035 Saarilahti, 2006, Sparing of the submandibular glands by intensity modulated radiotherapy in the treatment of head and neck cancer, Radiother Oncol, 78, 270, 10.1016/j.radonc.2006.02.017 Jellema, 2005, Does radiation dose to the salivary glands and oral cavity predict patient-rated xerostomia and sticky saliva in head and neck cancer patients treated with curative radiotherapy?, Radiother Oncol, 77, 164, 10.1016/j.radonc.2005.10.002 Seikaly, 2004, Long-term outcomes of submandibular gland transfer for prevention of postradiation xerostomia, Arch Otolaryngol Head Neck Surg, 130, 956, 10.1001/archotol.130.8.956 Murdoch-Kinch, 2008, Dose–effect relationships for the submandibular salivary glands and implications for their sparing by intensity modulated radiotherapy, Int J Radiat Oncol Biol Phys, 72, 373, 10.1016/j.ijrobp.2007.12.033 Munter, 2007, Changes in salivary gland function after radiotherapy of head and neck tumors measured by quantitative pertechnetate scintigraphy: Comparison of intensity-modulated radiotherapy and conventional radiation therapy with and without amifostine, Int J Radiat Oncol Biol Phys, 67, 651, 10.1016/j.ijrobp.2006.09.035