Cells compete for Decapentaplegic survival factor to prevent apoptosis in Drosophila wing development

Morata, G. & Ripoll, P. Minutes: mutants of Drosophila autonomously affecting cell division rate. Dev. Biol. 42, 211–221 (1975).

Minami, M., Kinoshita, N., Kamoshida, Y., Tanimoto, H. & Tabata, T. brinker is a target of Dpp in Drosophila that negatively regulates Dpp-dependent genes. Nature 398, 242–246 (1999).

Jazwinska, A., Kirov, N., Wieschaus, E., Roth, S. & Rushlow, C. The Drosophila gene brinker reveals a novel mechanism of Dpp target gene regulation. Cell 96, 563–573 (1999).

Campbell, G. & Tomlinson, A. Transducing the Dpp morphogen gradient in the wing of Drosophila: regulation of Dpp targets by brinker. Cell 96, 553–562 (1999).

Conlon, I. & Raff, M. Size control in animal development. Cell 96, 235–244 (1999).

Lawrence, P. A. Morphogens: how big is the big picture? Nature Cell Biol. 3, 151–154 (2001).

Lambertsson, A. The Minute genes in Drosophila and their molecular functions. Adv. Genet. 38, 69–134 (1998).

Simpson, P. Parameters of cell competition in the compartments of the wing of Drosophila. Dev. Biol. 69, 182–193 (1979).

Simpson, P. & Morata, G. Differential mitotic rates and pattern of growth in compartments in the Drosophila wing. Dev. Biol. 85, 299–308 (1981).

Böhni, R. et al. Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4. Cell 97, 865–875 (1999).

Johnston, L. A., Prober, D. A., Edgar, B. A., Eisenman, R. N. & Gallant, P. Drosophila myc regulates cellular growth during development. Cell 98, 779–790 (1999).

Prober, D. & Edgar, B. ras1 promotes cellular growth in the Drosophila wing. Cell 100, 435–446 (2000).

Neufeld, T. P., de la Cruz, A. F., Johnston, L. A. & Edgar, B. A. Coordination of growth and cell division in the Drosophila wing. Cell 93, 1183–1193 (1998).

Gavrieli, Y., Sherman, Y. & Ben-Sasson, S. A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119, 493–501 (1992).

Hay, B. A., Wolff, T. & Rubin, G. M. Expression of baculovirus p35 prevents cell death in Drosophila. Development 120, 2121–2129 (1994).

Adachi-Yamada, T., Fujimura-Kamada, K., Nishida, Y. & Matsumoto, K. Distortion of proximodistal information causes JNK-dependent apoptosis in Drosophila wing. Nature 400, 166–169 (1999).

Martin-Blanco, E. et al. puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila. Genes Dev. 12, 557–570 (1998).

Glise, B., Bourbon, H. & Noselli, S. hemipterous encodes a novel Drosophila MAP kinase kinase, required for epithelial cell sheet movement. Cell 83, 451–461 (1995).

Burke, R. & Basler, K. Dpp receptors are autonomously required for cell proliferation in the entire developing Drosophila wing. Development 122, 2261–2269 (1996).

Zhang, H., Levine, M. & Ashe, H. L. Brinker is a sequence-specific transcriptional repressor in the Drosophila embryo. Genes Dev. 15, 261–266 (2001).

Tanimoto, H., Itoh, S., ten Dijke, P. & Tabata, T. Hedgehog creates a gradient of DPP activity in Drosophila wing imaginal discs. Mol. Cell 5, 59–71 (2000).

Tsukazaki, T., Chiang, T. A., Davidson, A. F., Attisano, L. & Wrana, J. L. SARA, a FYVE domain protein that recruits Smad2 to the TGF-β receptor. Cell 95, 779–791 (1998).

Entchev, E. V., Schwabedissen, A. & Gonzalez-Gaitan, M. Gradient formation of the TGF-β homolog Dpp. Cell 103, 981–991 (2000).

Struhl, G., Barbash, D. A. & Lawrence, P. A. Hedgehog acts by distinct gradient and signal relay mechanisms to organise cell type and cell polarity in the Drosophila abdomen. Development 124, 2155–2165 (1999).

Raff, M. C. Social controls on cell survival and cell death. Nature 356, 397–400 (1992).

Adams, M. D. et al. The genome sequence of Drosophila melanogaster. Science 287, 2185–2195 (2000).

Milán, M., Campuzano, S. & García-Bellido, A. Developmental parameters of cell death in the wing disc of Drosophila. Proc. Natl Acad. Sci. USA 94, 5691–5696 (1997).