EcoRI Restriction Fragment-Length Polymorphism of the Human Immunoglobulin Variable Lambda 8 (IGLV8) Subgroup Reveals a Gene Family

Kabat EA, Wu TT, Perry HM, Gottesman KS, Foeller C: Sequences of Proteins of Immunological Interest. US Department of Health and Human Services, NIH, Public Health Service, Washington, D.C., 1991. Lai, 1989, Physical maps of the mouse and human immunoglobulin like loci, Adv Immunol, 46, 1, 10.1016/S0065-2776(08)60650-1 McBride, 1982, Chromosomal location of human kappa and lambda immunoglobulin light chain constant region genes, J Exper Med, 155, 1480, 10.1084/jem.155.5.1480 de la Chapelle, 1983, Lambda Ig constant region genes are translocated to chromosome 8 in Burkitt’s lymphoma with t(8,22), Nucleic Acids Res, 11, 1133, 10.1093/nar/11.4.1133 Alexandre, 1989, First genomic sequence of a human Ig variable λ gene belonging to subgroup I, Nucleic Acids Res, 17, 3975, 10.1093/nar/17.10.3975 Bauer, 1991, The human λ L chain Ig locus, J Immunol, 146, 2813, 10.4049/jimmunol.146.8.2813 Combriato, 1991, Vλ and Jλ-Cλ gene segments of the human immunoglobulin λ light chain locus are separated by 14 kb and rearrange by a deletion mechanism, J Immunol, 21, 1513 Dariavach, 1987, Human immunoglobulin Cλ6 gene encodes the Kern Oz λ chain and Cλ4 and Cλ5 are pseudogenes, Proc Natl Acad Sci USA, 84, 9074, 10.1073/pnas.84.24.9074 Daley, 1992, Molecular analysis of human immunoglobulin VλIII and VλIV, Mol Immunol, 29, 1515, 10.1016/0161-5890(92)90226-N Daley, 1992, Molecular analysis of human immunoglobulin VλIII and VλIV, Mol Immunol, 29, 1515, 10.1016/0161-5890(92)90226-N Heiter, 1987, Clustered arrangement of immunoglobulin L constant region genes in man, Nature, 294, 536, 10.1038/294536a0 Vasicek, 1993, Structure and expression of the human immunoglobulin λ genes, J Exp Med, 172, 609, 10.1084/jem.172.2.609 Frippiat, 1994, Genomic organization of 34 kb of the human immunoglobulin lambda locus (IGLV), Mol Immunol, 31, 657, 10.1016/0161-5890(94)90175-9 Williams, 1996, Sequence and evolution of the human germline Vλ repertoire, J Mol Biol, 264, 220, 10.1006/jmbi.1996.0636 Siminovitch, 1989, A natural autoantibody is encoded by germline heavy and lambda light chain variable region genes without somatic mutation, J Clin Invest, 84, 1675, 10.1172/JCI114347 Bernard, 1990, Genomic sequence of IGLV1S2, a human immunoglobulin variable lambda gene belonging to subgroup I, Nucleic Acids Res, 18, 7139, 10.1093/nar/18.23.7139 Williams, 1993, Cloning and sequencing of human immunoglobulin Vλ segments, Eur J Immunol, 23, 1456, 10.1002/eji.1830230709 Broclky, 1989, First nucleotidic sequence of a human immunoglobulin variable lambda gene belonging to subgroup II, Nucleic Acids Res, 17, 3976, 10.1093/nar/17.10.3976 Frippiat, 1990, First genomic sequence of a human Ig variable lambda gene belonging to subgroup III, Nucleic Acids Res, 18, 7134, 10.1093/nar/18.23.7134 Anderson, 1984, The isolation of a human IGVλ gene from a recombinant library of chromosome 22 and estimation of its copy number, Nucleic Acids Res, 12, 6647, 10.1093/nar/12.17.6647 Winter, 1992, Analysis of immunoglobulin variable region genes from human IgG anti-DNA hybridomas, Eur J Immunol, 22, 1719, 10.1002/eji.1830220709 Stiernholm, 1994, Identification of a new human Vλ gene family—VλX, J Immunol, 152, 4969, 10.4049/jimmunol.152.10.4969 Chuchana, 1990, Definition of the human immunoglobulin variable lambda (IGLV) gene subgroups, Eur J Immunol, 20, 1317, 10.1002/eji.1830200618 Shows, 1987, Guidelines for human gene nomenclature. An international system for human gene nomenclature (ISGN, 1987). (9th International Workshop on Human gene Mapping.), Cytogenet Cell Genet, 46, 11 Frippiat, 1995, Organization of the human immunoglobulin lambda light-chain locus on chromosome 22q11, Hum Mol Genet, 4, 983, 10.1093/hmg/4.6.983 Kawasaki, 1995, The organization of the human immunoglobulin λ gene locus, Genome Res, 5, 125, 10.1101/gr.5.2.125 Chuchana, 1991, The IGLVA gene as an STS in the human immunoglobulin lambda light chain variable gene locus (located at 22q11), Nucleic Acids Res, 19, 4786, 10.1093/nar/19.17.4786 Passos, 1994, Definition of a sequence-tagged site for the human immunoglobulin IGLV9S1 gene located at chromosome 22q11, Exp Clin Immunogenet, 11, 222 Poul, 1991, The IGLJ6 joining segment as a STS in the human immunoglobulin lambda light chain constant region gene locus (located at 22q11), Nucleic Acids Res, 19, 4785, 10.1093/nar/19.17.4785 Ghanem, 1988, Definition of RFLP alleles in the human immunoglobulin IGHG gene locus, Eur J Immunol, 18, 1054, 10.1002/eji.1830180714 Sambrook, 1989 Sanger, 1977, DNA sequencing with chain terminating inhibitor, Proc Natl Acad Sci USA, 74, 5463, 10.1073/pnas.74.12.5463 Queiroz RGP, Brûlé A, Passos Jr GAS: RFLP analysis and cloning genomic segments containing members of human lambda light-chain immunoglobulin genes. Braz. J. Genetics 19(3) supp.:295, 1996. Frippiat, 1994, Immunoglobulin lambda light chain orphons on human chromosome 8q11, Eur J Immunol, 27, 1260, 10.1002/eji.1830270530 Lee, 1994, Somatically mutated member of the human VλVIII gene family encodes anti-myelin associated glycoprotein (MAG) activity, J Neuroimmunol, 51, 45, 10.1016/0165-5728(94)90127-9