The Magnitude of Decrease in Hepatic Very Low Density Lipoprotein Apolipoprotein B Secretion Is Determined by the Extent of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibition in Miniature Pigs1

Endocrinology - Tập 140 Số 11 - Trang 5293-5302 - 1999
John R. Burnett1, Lisa J. Wilcox1, Dawn E. Telford1, Sandra J. Kleinstiver1, P. Hugh R. Barrett2, Roger S. Newton3, Murray W. Huff1
1Departments of Medicine and Biochemistry and The John P. Robarts Research Institute (J.R.B., L.J.W., D.E.T., S.J.K., M.W.H.), University of Western Ontario, London, Ontario, N6A 5K8 Canada
2Department of Medicine (P.H.R.B.), University of Western Australia, Perth, Western Australia, 6001 Australia
3Parke-Davis Pharmaceutical Research (R.S.N.), Warner Lambert Company, Ann Arbor, Michigan 48105

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