Infantile Hemangiomas: An Updated Review on Risk Factors, Pathogenesis, and Treatment

Birth Defects Research - Tập 109 Số 11 - Trang 809-815 - 2017
Chelsey J. Forbess Smith1, Sheila Fallon Friedlander2, Mónica Gumá1, Arthur Kavanaugh1, Christina Chambers3,4
1Department of Rheumatology, University of California San Diego, San Diego, California
2Department of Pediatric and Adolescent Dermatology, University of California San Diego, San Diego, California
3Department of Family Medicine and Public Health, University of California, San Diego, San Diego, California
4Department of Pediatrics, University of California San Diego, San Diego, California

Tóm tắt

Infantile hemangiomas (IHs) are the most common vascular tumors in infants, appearing in early infancy and ultimately regressing with time. Clinical presentation may vary, with a minority of lesions causing impairment of vital function (e.g., respiratory or visual obstruction), permanent scarring, and/or disfigurement. The pathogenesis of IH is complex and poorly understood. Risk factors implicated in their development include preterm birth and placental anomalies. IH presents a myriad of clinical challenges, including correct diagnosis and whether or not to pursue treatment. This article is a review of the current literature regarding pathogenesis, clinical presentation, treatment, and prognosis of IH. Birth Defects Research 109:809–815, 2017. © 2017 Wiley Periodicals, Inc.

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Birth Defects Research

Tập 109 Số 11

809-815

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