Studies of the Mitogen-activated Protein Kinases and Phosphatidylinositol-3 Kinase in the Lens. 1. The Mitogenic and Stress Responses‡

Experimental Eye Research - Tập 74 - Trang 703-717 - 2002
D. Steven Zatechka1, Marjorie F. Lou1,2,3
1Department of Veterinary and Biomedical Sciences, University of Nebraska–Lincoln, Lincoln, NE, 68583-0905, U.S.A.
2Department of Biochemistry, University of Nebraska–Lincoln, Lincoln, NE, 68583-0905, U.S.A.
3Department of Ophthalmology, University of Nebraska Medical Center, Omaha, NE, 68198, U.S.A.

Tài liệu tham khảo

Bhuyan, 2000, Growth factor receptor gene and protein expressions in the human lens, Mech. Ageing Dev., 113, 205, 10.1016/S0047-6374(99)00111-6 Blumer, 1994, Diversity in function and regulation of MAP kinase pathways, Trends Biochem., 56, 236, 10.1016/0968-0004(94)90147-3 Brunet, 1999, Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry, EMBO J., 18, 664, 10.1093/emboj/18.3.664 Chamberlain, 1991, The effects of insulin and basic fibroblast growth factor on fibre differentiation in rat lens epithelial explants, Growth Factors, 4, 183, 10.3109/08977199109104814 Chandrasekher, 2000, Phosphatidylinositol 3-kinase in bovine lens and its stimulation by insulin and IGF-1, Invest. Ophthalmol. Vis. Sci., 41, 844 Cobbs, 1995, How MAP kinases are regulated, J. Biol. Chem., 270, 14843, 10.1074/jbc.270.25.14843 Derijard, 1994, JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain, Cell, 76, 1025, 10.1016/0092-8674(94)90380-8 Dhand, 1994, PI3-kinase: structural and functional analysis of intersubunit interactions, EMBO J., 13, 511, 10.1002/j.1460-2075.1994.tb06289.x Duckworth, 1997, Conditional inhibition of the mitogen-activated protein kinase cascade by wortmannin, J. Biol. Chem., 272, 27665, 10.1074/jbc.272.44.27665 Duncan, 1994, Calcium, cell signaling and cataract, Prog. Ret. Eye Res., 13, 623, 10.1016/1350-9462(94)90025-6 Fantl, 1992, Distinct phosphotyrosines on growth factor receptor bind to specific molecules that mediate different signaling pathways, Cell, 69, 413, 10.1016/0092-8674(92)90444-H Freshney, 1994, Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27, Cell, 78, 1039, 10.1016/0092-8674(94)90278-X Galcheva-Gargova, 1994, An osmosensing signal trasduction pathway in mammalian cells, Science, 265, 806, 10.1126/science.8047888 Gong, 2001, Development of cataractous macrophthalmia in mice expressing an active MEK1 in the lens, Invest. Ophthalmol. Vis. Sci., 42, 539 Gonzalez-Charneco, 1998, Localization of protein kinase C in normal and galactosemic bovine lens epithelial cells in culture, Histochem. Cell Biol., 110, 89, 10.1007/s004180050269 Gutkind, J. S. 2000, Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors, http://www.stke.org/cgi/content/full/OC_sigtrans;2000/40/rel Han, 1994, A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells, Science, 265, 808, 10.1126/science.7914033 Heldin, 1995, Dimerization of cell surface receptors in signal transduction, Cell, 80, 213, 10.1016/0092-8674(95)90404-2 Huang, 1996, MAP kinases in multiple signaling pathways, 159 Ibaraki, 1996, A study of growth factor receptors in human lens epithelial cells and their relationship to fiber differentiation, Exp. Eye Res., 63, 683, 10.1006/exer.1996.0162 Jacobs, 1994, Effect of aging on insulin-like growth factor one binding to its receptor and its subsequent potentiation of receptor tyrosine kinase activity in human lens, Invest. Ophthalmol. Vis. Sci., Suppl. 35, s2205 Kashishian, 1992, Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo, EMBO J., 11, 1373, 10.1002/j.1460-2075.1992.tb05182.x Kennedy, 1997, The PI3-kinase/Akt signaling pathway delivers an anti-apoptotic signal, Genes Dev., 11, 701, 10.1101/gad.11.6.701 Kinoshita, 1964, Mechanisms initiating cataract formation, Invest. Ophthalmol., 13, 713 Klok, 1998, Induction and maintenance of differenctiation of rat lens epithelium by FGF-2, insulin and IGF-1, Exp. Eye Res., 67, 425, 10.1006/exer.1998.0534 Kyriakis, 1994, The stress-activated protein kinase subfamily of c- jun kinases, Nature, 369, 156, 10.1038/369156a0 Le, 2001, A novel role for FGF and extracellular signal-regulated kinase in gap junction-mediated intercellular communication in the lens, J. Cell Biol., 154, 197, 10.1083/jcb.200101057 Lee, X. R. Kosaka, M. Majima, Y. Sawada, M. 1994, Detection of basic fibroblast growth factor receptor on bovine lens epithelial cells, 5 Li, 1995, Lens epithelial cell apoptosis appears to be a common cellular basis for non-congenital cataract development in humans and animals, J. Cell Biol., 130, 169, 10.1083/jcb.130.1.169 Lopez-Ilasaca, 1997, Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase γ, Science, 275, 394, 10.1126/science.275.5298.394 Lou, 1989, The prevention of biochemical changes in lens, retina, and nerve of galactosemic dogs by the aldose reductase inhibitor AL01576, J. Ocu. Pharmacol., 5, 233, 10.1089/jop.1989.5.233 McAvoy, 1989, Fibroblast growth factor (FGF) induces different responses in lens epithelial cells depending on its concentration, Development, 107, 221, 10.1242/dev.107.2.221 Moses, 1990, TGF-β stimulation and inhibition of cell proliferation: new mechanistic insights, Cell, 63, 245, 10.1016/0092-8674(90)90155-8 Pimentel, 1994, Platelet-derived growth factor Potts, 1994, Expression of platelet-derived growth factor receptors in the developing chicken lens, Invest. Ophthalmol. Vis. Sci., Suppl. 35, 3413 Rao, 1997, Analysis of small GTP-binding proteins of the lens by GTP overlay assay reveals the presence of unique GTP-binding proteins associated with fiber cells, Exp. Eye Res., 64, 219, 10.1006/exer.1996.0197 Rossomando, 1989, Evidence that pp42, a major tyrosine kinase target protein, is a mitogen-activated serine/threonine protein kinase, Proc. Nat. Acad. Sci. U.S.A., 86, 6940, 10.1073/pnas.86.18.6940 Seger, 1995, The MAPK signaling cascade, FASEB J., 9, 726, 10.1096/fasebj.9.9.7601337 Sluss, 1994, Signal transduction by tumor necrosis factor mediated by JNK protein kinases, Mol. Cell. Biol., 14, 8376, 10.1128/MCB.14.12.8376 Smith, 1985, Measurement of protein concentration using bicinchoninic acid, Anal. Biochem., 150, 76, 10.1016/0003-2697(85)90442-7 Souttou, 1997, Signal transduction pathways involved in the mitogenic activity of pleiotrophin. Implications of mitogen-activated protein kinase and phosphoinositide 3-kinase pathways, J. Biol. Chem., 272, 19588, 10.1074/jbc.272.31.19588 Toker, 2000, Protein kinases as mediators of phosphoinositide 3-kinase signaling, Mol. Pharmacol., 57, 652, 10.1124/mol.57.4.652 Tripathi, 1992, Detection, quantification, and significance of basic fibrobalast growth factor in the aqueous humor of man, cat, dog and pig, Exp. Eye Res., 54, 447, 10.1016/0014-4835(92)90056-X Tumminia, 1994, The integrity of mammalian lenses in organ culture, Exp. Eye Res., 58, 367, 10.1006/exer.1994.1027 Ullrich, 1990, Signal transduction by receptors with tyrosine kinase activity, Cell, 61, 203, 10.1016/0092-8674(90)90801-K Vanhaesebroeck, 1997, Phosphoinositide 3-kinases: a conserved family of signal transducers, Trends Biochem. Sci., 22, 267, 10.1016/S0968-0004(97)01061-X Vivekanandan, 1989, Evidence for the presence of phosphoinositide cycle and its involvement in cellular signal transduction in the rabbit lens, Curr. Eye Res., 8, 101, 10.3109/02713688909013899 Whitmarsh, 1995, Integration of MAP kinase signal transduction pathways at the serum response element, Science, 269, 403, 10.1126/science.7618106 Widmann, 1999, Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human, Physiol. Rev., 79, 143, 10.1152/physrev.1999.79.1.143 Wride, 1996, Cellular and molecular features of lens differentiation: a review of recent advances, Differentiation, 61, 77, 10.1046/j.1432-0436.1996.6120077.x Wymann, 1998, Review: structure and function of phosphoinositide 3-kinases, Biochim. Biophys. Acta, 1436, 127, 10.1016/S0005-2760(98)00139-8 Zatechka, 1999, Activation of mitogen-activated protein kinase in the lens in response to mitogenic signals, Invest. Ophthalmol. Vis. Sci., Suppl. 40, S885 Zimmermann, 1999, Phosphorylation and regulation of Raf by Akt (protein kinase B), Science, 286, 1741, 10.1126/science.286.5445.1741