Huge malignant phyllodes breast tumor: a real entity in a new era of early breast cancer
Tóm tắt
Phyllodes tumor is an extremely rare tumor of the breast. It occurs in females in the third and fourth decades. The difficulty in distinguishing between phyllodes tumors and benign fibroadenoma may lead to misdiagnosis. Lymph node involvement is rarely described in phyllodes tumors; for this reason, sentinel node biopsy may be warranted. We present a case of a 33-year-old woman affected by huge tumor of the right breast with ulceration in the skin with a rapid tumor growth and with omolateral axillary metastasis.
Tài liệu tham khảo
Moffat CJ, Pinder SE, Dixon AR, Elston CW, Blamey RW, Ellis IO. Phyllodes tumours of the breast: a clinico pathological review of thirty two cases. Histopathology. 1995;27(3):205–18.
Bellocq JP, Magro G. Fibroepithelial tumors. In: Tavassoli FA, Devilee P, editors. World Health Organization Classification of Tumors: Tumors of the Breast and Female Genital Organs. Lyon, France: IARC; 2003. p. 99–103.
Grabowski J, Salzsrein SL, Sadler GR, Blair SL. Malignant phyllodes tumors: a review of 752 cases. Am Surg. 2007;73:967–9.
Salvadori B, Cusumano F, Del Bo R, Delledonne V, Grassi M, Rovini D, et al. Surgical treatment of phyllodes tumors of the breast. Cancer. 1989;63(12):2532–6.
Reinfuss M, Mitus J, Duda K, Stelmach A, Rys J, Smolak K. The treatment and prognosis of patients with phyllodes tumor of the breast: an analysis of 170 cases. Cancer. 1996;77(5):910–6.
Cohn-Cedermark G, Rutqvist LE, RosendahL I, Silfsverswärd C. Prognostic factors in cystosarcoma phyllodes: a clinicopathologic study of 77 patients. Cancer. 1991;68:2017–22.
Buchberger W, Strasser K, Heim K, Müller E, Schröcksnadel H. Phylloides tumor: findings on mammography, sonography, and aspiration cytology in 10 cases. AJR. 1991;157(4):715–9.
Lenhard MS, Kahlert S, Himsl I, Ditsch N, Untch M, Bauerfeind I. Phyllodes tumour of the breast: clinical follow-up of 33 cases of this rare disease. Eur J Obstet Gynecol Reprod Biol. 2008;138(2):217–21.
Ramakant P, Chakravarthy S, Cherian JA, Abraham DT, Paul MJ. Challenges in management of phyllodes tumors of the breast: a retrospective analysis of 150 patients. Indian J Cancer. 2013;50(4):345–8.
Spitaleri G, Toesca A, Botteri E, Bottiglieri L, Rotmensz N, Boselli S, et al. Breast phyllodes tumor: a review of literature and a single center retrospective series analysis. Crit Rev Oncol Hematol. 2013;88(2):427–36.
Barrio AV, Clark BD, Goldberg JI, Hoque LW, Bernik SF, Flynn LW, et al. Clinicopathologic features and long-term outcomes of 293 phyllodes tumors of the breast. Ann Surg Oncol. 2007;14(10):2961–70.
Mangi AA, Smith BL, Gadd MA, Tanabe KK, Ott MJ, Souba WW. Surgical management of phyllodes tumors. Arch Surg. 1999;134(5):487–92.
Kapiris I, Nasiri N, A’Hern R, Healy V, Gui GP. Outcome and predictive factors of local recurrence and distant metastases following primary surgical treatment of high-grade malignant phyllodes tumours of the breast. Eur J Surg Oncol. 2001;27(8):723–30.
Grimes MM. Cystosarcoma phyllodes of the breast: histologic features, flow cytometric analysis, and clinical correlations. Mod Pathol. 1992;5(3):232–9.
Rowell MD, Perry RR, Hsiu JG, Barranco SC. Phyllodes tumors. Am J Surg. 1993;165(3):376–9.
Pandy M, Matthew A, Jayabreek I. Malignant phyllodes tumor. Breast Journal. 2001;71:411–6.
Holthouse DJ, Smith PA, Naunton-Morgan R, Minchin D. Cystosarcoma phyllodes: the Western Australian experience. Aust NZJ Surg. 1999;69(9):635–8.
Parker SJ, Harries SA. Phyllodes tumours. Postgrad Med J. 2001;77(909):428–35.
Barrow BJ, Janjan NA, Gutman H, Benjamin RS, Allen P, Romsdahl MM, et al. Role of radiotherapy in sarcoma of the breast–a retrospective review of the M.D. Anderson experience. Radiother Oncol. 1999;52:173–8.
Asoglu O, Ugurlu MM, Blanchard K, Grant CS, Reynolds C, Cha SS, et al. Risk factors for recurrence and death after primary surgical treatment of malignant phyllodes tumors. Ann Surg Oncol. 2004;11(11):1011–7.
Stockdale AD, Leader M. Phyllodes tumour of the breast: response to radiotherapy. Clin Radiol. 1987;38(3):287.