Enzyme-responsive destabilization of stabilized plasmid-lipid nanoparticles as an efficient gene delivery

Ambegia, 2005, Stabilized plasmid–lipid particles containing PEG-diacylglycerols exhibit extended circulation lifetimes and tumor selective gene expression, Biochim. Biophys. Acta Biomembr., 1669, 155, 10.1016/j.bbamem.2005.02.001 Blenke, 2013, Strategies for triggered drug release from tumor targeted liposomes, Informa Healthc., 10, 1399 Choi, 2003, Low-pH-sensitive PEG-stabilized plasmid-lipid nanoparticles: preparation and characterization, Bioconjug. Chem., 14, 420, 10.1021/bc025625w Davis, 2002, Non-viral gene delivery systems, Curr. Opin. Biotechnol., 13, 128, 10.1016/S0958-1669(02)00294-X Fenske, 2002, Stabilized plasmid-lipid particles: a systemic gene therapy vector, 36, 10.1016/S0076-6879(02)46048-X Gao, 1995, Cationic liposome-mediated gene transfer, Gene Ther., 2, 710 Gondi, 2013, Cathepsin B as a cancer target, Expert Opin. Ther. Targets, 17, 281, 10.1517/14728222.2013.740461 Guo, 2001, Steric stabilization of fusogenic liposomes by a low-pH sensitive PEG–diortho ester–lipid conjugate, Bioconjug. Chem., 12, 291, 10.1021/bc000110v Hamley, 2014, PEG-peptide conjugates, Biomacromolecules, 15, 1543, 10.1021/bm500246w Hirko, 2003, Cationic lipid vectors for plasmid DNA delivery, Curr. Med. Chem., 10, 1185, 10.2174/0929867033457412 Hofland, 1997, In vivo gene transfer by intravenous administration of stable cationic lipid DNA complex, Pharm. Res., 14, 742, 10.1023/A:1012146305040 Kato, 2013, Acidic extracellular microenvironment and cancer, Cancer Cell Int., 13, 89, 10.1186/1475-2867-13-89 Kim, 2013, Liposomal doxorubicin-loaded chitosan microspheres capable of controlling release of doxorubicin for anti-cancer chemoembolization: in vitro characteristics, J. Drug Delivery Sci. Technol., 23, 283, 10.1016/S1773-2247(13)50042-6 Kumar, 2003, Cationic transfection lipids in gene therapy: successes, set-backs, challenges and promises, Curr. Med. Chem., 10, 1297, 10.2174/0929867033457458 Li, 2005, Low-pH-sensitive poly(ethylene glycol) (PEG)-stabilized plasmid nanolipoparticles: effects of PEG chain length, lipid composition and assembly conditions on gene delivery, J. Gene Med., 7, 67, 10.1002/jgm.634 Lv, 2006, Toxicity of cationic lipids and cationic polymers in gene delivery, J. Control. Release, 114, 100, 10.1016/j.jconrel.2006.04.014 Mok, 1999, Stabilized plasmid-lipid particles: factors influencing plasmid entrapment and transfection properties, Biochim. Biophys. Acta Biomembr., 1419, 137, 10.1016/S0005-2736(99)00059-0 Monck, 2000, Stabilized plasmid-lipid particles: pharmacokinetics and plasmid delivery to distal tumors following intravenous injection, J. Drug Target., 7, 439, 10.3109/10611860009102218 Muzylak, 2007, The in vitro effect of pH on osteoclasts and bone resorption in the cat: implications for the pathogenesis of FORL, J. Cell. Physiol., 213, 144, 10.1002/jcp.21103 Ropert, 1999, Liposomes as a gene delivery system, Braz. J. Med. Biol. Res., 32, 163, 10.1590/S0100-879X1999000200004 Schmidt-Wolf, 2003, Non-viral and hybrid vectors in human gene therapy: an update, Trends Mol. Med., 9, 67, 10.1016/S1471-4914(03)00005-4 Shim, 2013, Application of cationic liposomes for delivery of nucleic acids, Asian J. Pharm. Sci., 8, 72, 10.1016/j.ajps.2013.07.009 Taunton, 2000, Actin-dependent propulsion of endosomes and lysosomes by recruitment of N-WASP, J. Cell Biol., 148, 519, 10.1083/jcb.148.3.519 Templeton, 1999, New directions in liposome gene delivery, Mol. Biotechnol., 11, 175, 10.1007/BF02915810 Tirosh, 1998, Hydration of polyethylene glycol-grafted liposomes, Biophys. J., 74, 1371, 10.1016/S0006-3495(98)77849-X Veronese, 2005, PEG-doxorubicin conjugates: influence of polymer structure on drug release, in vitro cytotoxicity, biodistribution, and antitumor activity, Bioconjug. Chem., 16, 775, 10.1021/bc040241m Wheeler, 1999, Stabilized plasmid-lipid particles: construction and characterization, Gene Ther., 6, 271, 10.1038/sj.gt.3300821 Yan, 1998, Cathepsin B and human tumor progression, Biol. Chem., 379, 113 Yuan, 2015, A photoactivatable AIE polymer for light-controlled gene delivery: concurrent endo/lysosomal escape and DNA unpacking, Angew. Chem. Int. Ed. Eng., 54, 11419, 10.1002/anie.201503640 Zelphati, 1998, Stable and monodisperse lipoplex formulations for gene delivery, Gene Ther., 5, 1272, 10.1038/sj.gt.3300707 Zhang, 1999, Stabilized plasmid-lipid particles for regional gene therapy: formulation and transfection properties, Gene Ther., 6, 1438, 10.1038/sj.gt.3300965 Zhang, 2015, pH-sensitive ternary nanoparticles for nonviral gene delivery, RSC Adv., 5, 44291, 10.1039/C5RA04745E