Practical Guidelines: Lung Transplantation in Patients with Cystic Fibrosis

Pulmonary Medicine - Tập 2014 - Trang 1-22 - 2014
Tim O. Hirche1, Christian Benden2, Helge Hebestreit3, D. Shimmin4, Amparó Solé5, J.S. Elborn6, Helmut Ellemunter7, Paul Aurora8, Michael Hogardt9, Thomas Wagner10,11, ECORN-CF Study Group10
1Department of Pulmonary Medicine, German Clinic for Diagnostics (DKD), Wiesbaden, Germany
2Department of Chest Medicine, Erasme University Hospital, Brussels, Belgium
3Department of Pediatrics, University Hospital Wuerzburg, Germany
4Regional Adult CF Centre, Belfast City Hospital, Belfast, UK
5Lung Transplant Unit, Hospital Universitario La Fe, Valencia, Spain.
6Centre for Infection and Immunity, Queens University, Belfast and Adult CF Centre BHSCT, UK
7Cystic Fibrosis Center, Department of Pediatrics, Medical University Innsbruck, Innsbruck, Austria
8Paediatric Respiratory Medicine and Lung Transplantation, Great Ormond Street Hospital, London, UK
9Institute for Medical Microbiology and Infection Control, Goethe University Hospital Frankfurt, Germany
10Department of Pneumology, Frankfurt University Hospital, Building 15B,Theodor-Stern-Kai 7, 60590 Frankfurt, Germany
11Department of Pneumology, Goethe University Hospital Frankfurt, Germany

Tóm tắt

There are no European recommendations on issues specifically related to lung transplantation (LTX) in cystic fibrosis (CF). The main goal of this paper is to provide CF care team members with clinically relevant CF-specific information on all aspects of LTX, highlighting areas of consensus and controversy throughout Europe. Bilateral lung transplantation has been shown to be an important therapeutic option for end-stage CF pulmonary disease. Transplant function and patient survival after transplantation are better than in most other indications for this procedure. Attention though has to be paid to pretransplant morbidity, time for referral, evaluation, indication, and contraindication in children and in adults. This review makes extensive use of specific evidence in the field of lung transplantation in CF patients and addresses all issues of practical importance. The requirements of pre-, peri-, and postoperative management are discussed in detail including bridging to transplant and postoperative complications, immune suppression, chronic allograft dysfunction, infection, and malignancies being the most important. Among the contributors to this guiding information are 19 members of the ECORN-CF project and other experts. The document is endorsed by the European Cystic Fibrosis Society and sponsored by the Christiane Herzog Foundation.

Từ khóa


Tài liệu tham khảo

2012, The Journal of Heart and Lung Transplantation, 31, 1073, 10.1016/j.healun.2012.08.004

10.1016/j.healun.2006.03.011

10.1164/rccm.200407-900OC

10.1055/s-0029-1214821

10.1097/MCP.0b013e32834b8bdb

2011, Deutsches Ärzteblatt, 108, B2037

10.1016/S1053-2498(01)00241-8

1998, The Journal of Heart and Lung Transplantation, 17, 703

10.1111/j.1600-6143.2006.01276.x

10.1164/rccm.200810-1603OC

10.1183/09031936.03.00039003

10.1016/j.rmed.2008.11.015

10.1136/thx.2008.104711

10.1016/j.jcf.2011.10.009

1997, Thorax, 52, 318, 10.1136/thx.52.4.318

1998, Chest, 113, 217, 10.1378/chest.113.1.217

10.2500/ajr.2008.22.3146

10.1097/TP.0b013e3182193cd3

10.1016/j.athoracsur.2005.12.026

10.1097/MOT.0b013e3283592684

10.1111/j.1600-6143.2009.02779.x

10.1016/j.healun.2008.07.014

2010, The Journal of Heart and Lung Transplantation, 29, 1026, 10.1016/j.healun.2010.05.005

1998, The Journal of Heart and Lung Transplantation, 17, 1097

10.1016/S1053-2498(02)00667-8

1993, Annals of Thoracic Surgery, 55, 1087, 10.1016/0003-4975(93)90012-7

1997, The American Journal of Respiratory and Critical Care Medicine, 155, 1699, 10.1164/ajrccm.155.5.9154879

10.1016/j.healun.2007.05.018

10.1136/thx.2007.089458

10.1111/j.1600-6143.2008.02186.x

10.1016/j.healun.2010.06.007

10.1164/rccm.200712-1834OC

10.1111/j.1399-3062.2012.00726.x

10.1510/icvts.2011.271874

10.1111/j.1472-765X.2007.02130.x

10.1016/j.jcf.2010.03.008

10.1136/thorax.56.10.746

2001, Journal of the American Dietetic Association, 101, 438, 10.1016/S0002-8223(01)00113-4

1988, Journal of Clinical Epidemiology, 41, 583, 10.1016/0895-4356(88)90063-7

10.1164/rccm.200903-0425OC

10.1016/S1053-2498(00)00315-6

10.1034/j.1399-3003.2000.16f05.x

1993, The Journal of Heart and Lung Transplantation, 12, 669

1997, Journal of the Royal Society of Medicine, Supplement, 90, 47

1993, Chest, 103, 1819, 10.1378/chest.103.6.1819

2004, Nutrition in Clinical Practice, 19, 587, 10.1177/0115426504019006587

10.1016/S1569-1993(03)00020-1

10.1378/chest.09-2940

10.1002/1099-0496(200012)30:6<453::AID-PPUL3>3.0.CO;2-8

10.1016/j.jpsychores.2008.04.009

10.1007/s00108-004-1292-6

1999, Psychosomatics, 40, 293, 10.1016/S0033-3182(99)71221-1

2008, Journal of Cystic Fibrosis, 7, 106

10.1016/S1569-1993(11)60008-8

1997, Die psychosomatische Evaluation von Lebertransplantationspatienten. Anwendungsmöglichkeiten der Transplant-Evaluation-Ratings-Scale

10.1016/j.jcf.2007.07.008

10.1016/j.jcf.2009.11.006

10.1023/B:TAJP.0000041262.36839.fd

2010, Journal of Cystic Fibrosis, 9, 104, 10.1016/j.jcf.2009.11.009

10.1055/s-2003-812589

10.1016/j.transproceed.2010.03.117

10.1016/j.athoracsur.2011.04.122

10.1097/TP.0b013e318246f8e1

10.1016/j.healun.2011.04.014

10.1097/MOT.0b013e32834a99ac

10.1111/j.1600-6143.2012.04027.x

10.1016/j.athoracsur.2008.09.049

10.1056/NEJMoa1014597

10.1016/j.healun.2005.04.018

10.1513/pats.200808-083GO

10.1183/09031936.00143512

10.1016/S1052-3359(03)00059-0

10.1016/j.ejcts.2003.11.009

1995, Transplantation, 59, 707, 10.1097/00007890-199503150-00012

10.1016/j.athoracsur.2013.04.030

10.1111/j.1432-2277.2011.01401.x

10.1016/j.ejcts.2006.11.049

10.1111/j.1600-6143.2011.03946.x

10.1016/j.healun.2004.11.049

10.1016/j.healun.2007.07.018

2013, F1000Prime Reports, 5, 16

2001, Journal of the American Society of Echocardiography, 14, 806, 10.1067/mje.2001.111855

10.1016/j.echo.2006.10.024

10.1016/j.healun.2007.01.009

10.1016/j.healun.2006.09.021

10.1016/0003-4975(95)00823-3

10.1016/j.athoracsur.2011.01.077

10.1513/pats.200808-094GO

10.1016/j.ccm.2011.03.001

10.1111/j.1399-3046.2012.01682.x

10.1016/j.transproceed.2009.06.016

2002, Adult heart and lung transplantation, 31

1997, The Nursing clinics of North America, 32, 863, 10.1016/S0029-6465(22)02697-4

2012, Drug Design, Development and Therapy, 6, 151

10.1097/01.TP.0000151660.69796.10

10.1097/TP.0b013e31822790e3

10.1111/j.1399-0012.2005.00420.x

2004, Chest, 125, 1S, 10.1378/chest.125.1_suppl.1S

10.1378/chest.123.1.37

10.1016/S1569-1993(11)60005-2

10.1016/j.jcf.2004.12.002

10.1016/j.transproceed.2011.02.069

10.1111/j.1464-5491.2012.03676.x

10.1016/j.jcf.2011.10.005

10.1007/s11894-010-0106-3

10.1097/MOT.0b013e328357f84f

10.1067/mtc.2003.166

10.1016/j.amjsurg.2012.07.019

10.1016/j.healun.2010.10.005

10.1016/j.healun.2011.08.002

10.1513/pats.200808-080GO

10.1097/TP.0b013e3181d05a71

10.1055/s-2001-16982

10.1016/j.healun.2007.10.017

10.1055/s-0030-1249117

10.1016/S1053-2498(02)00398-4

1996, The Journal of Heart and Lung Transplantation, 15, 371

10.1183/09031936.00128607

2000, The American Journal of Respiratory and Critical Care Medicine, 161, 1937, 10.1164/ajrccm.161.6.9909092

10.1016/j.ccm.2011.02.009

10.1016/j.healun.2011.01.712

10.1016/j.healun.2011.08.004

2013, The American Journal of Transplantation, 13, 3

10.1111/j.1399-3062.2010.00525.x

10.1016/j.healun.2009.01.019

1997, Chest, 112, 924, 10.1378/chest.112.4.924

10.1016/j.transproceed.2011.03.075

10.1111/j.1600-6143.2006.01694.x

10.1111/j.1399-0012.2009.01076.x

10.1097/01.qco.0000136933.67920.dd

10.1164/rccm.200911-1786OC

2010, Cytomegalovirus infection after solid organ transplantation, 328

10.1097/TP.0b013e3181cee42f

10.1128/CMR.18.1.44-69.2005

10.1378/chest.121.3.988

10.1097/MCP.0b013e328326f410

2012, Mold infections in cardiothoracic transplantation, 195

2012, Transplantation, 94, 281, 10.1097/TP.0b013e318255f864

10.1056/NEJMoa020191

2010, HIV/AIDS, 2, 123

10.1111/j.1399-3062.2007.00269.x

10.1111/j.1399-0012.2010.01316.x

2013, Clinical Transplantation, 27, 303, 10.1111/ctr.12064

2013, The American Journal of Transplantation, 13, 42, 10.1111/ajt.12097

10.1164/rccm.201003-0422OC

10.1016/j.healun.2010.08.004

2003, Journal of the National Cancer Institute, 95, 381, 10.1093/jnci/95.5.381

10.1016/j.jcf.2011.05.003

10.1007/BF02698031

10.1016/S1470-2045(11)70300-X

1998, Physiotherapy

1994

2000, Journal of Pediatrics, 136, 304, 10.1067/mpd.2000.103408

10.1002/ppul.10015

10.1183/09031936.00062409

1991, International Journal of Rehabilitation Research, 14, 101, 10.1097/00004356-199106000-00002

10.1097/00005768-199703000-00004

2006, Annals of Internal Medicine, 145, 816, 10.7326/0003-4819-145-11-200612050-00006

2003, Pediatric Pulmonology, 36, 331

10.1034/j.1399-3003.2000.16f06.x

10.1111/j.1399-3046.2010.01471.x

2002, The American Journal of Respiratory and Critical Care Medicine, 165, 1629, 10.1164/rccm.2105090

10.3810/psm.2009.10.1732

2010, The American Journal of Respiratory and Critical Care Medicine, 181, article a1206

2009, Critical Care, 13, 216, 10.1186/cc7885

10.1055/s-2003-812526

10.1111/j.1600-6143.2008.02209.x

10.1111/j.1600-6143.2012.04000.x

1996, Physical Therapy, 76, 626, 10.1093/ptj/76.6.626

10.1378/chest.07-2934

2012, The Journal of Heart and Lung Transplantation, 31, 1087, 10.1016/j.healun.2012.08.005

10.1053/jhep.2002.37136

10.1002/hep.510300527

10.1046/j.1440-1746.2002.02671.x

10.1016/S1569-1993(11)60006-4

10.1016/j.jhep.2005.05.009

10.1111/j.1600-6143.2011.03904.x

10.1002/lt.23389

10.1111/j.1399-0012.2010.01395.x

10.1111/j.1600-6143.2007.01945.x

10.1016/S0022-5223(95)70064-1

2013, Archivos de Bronconeumología, 49, 272, 10.1016/j.arbres.2012.10.008

10.1016/j.transproceed.2005.09.091

10.1016/j.transproceed.2008.01.010

10.1111/j.1399-3046.2010.01412.x

2012, Progress in Transplantation, 22, 134, 10.7182/pit2012285

2009, Clinical Transplants, 65

10.1111/j.1600-6143.2011.03716.x

10.1016/j.transproceed.2008.10.043

2012, Journal of Cystic Fibrosis, 11, S27

10.2337/dc10-1768

10.1016/j.jcf.2010.08.013