Ebselen as Protection Against Ethanol-Induced Toxicity in Rat Stomach

Journal of Trace Elements in Medicine and Biology - Tập 13 - Trang 170-175 - 1999
Y.M.Y. ünlüçerçi1, R. Bulut1, S. Bekpinar1, L. Kuntsal2
1Department of Biochemistry, Istanbul Faculty of Medicine, University of Istanbul, 34390 Çapa, Istanbul, Turkey
2Department of Histology, Istanbul Faculty of Medicine, University of Istanbul, 34390 Çapa, Istanbul, Turkey

Tài liệu tham khảo

Sies, 1997, Ebselen as a glutathione peroxidase mimic and as a scavenger of peroxynitrite, Advances in Pharmacology, 38, 229, 10.1016/S1054-3589(08)60986-2 Safayhi, 1985, A novel biologically active seleno-organic compound V. Inhibition by ebselen (PZ 51) of rat peritoneal neutrophil lipoxygenase., Bio-chem. Pharmacol., 34, 2691, 10.1016/0006-2952(85)90569-6 Schewe, 1994, Strong inhibition of mammalian lipoxygenases by the anti-inflammatory seleno-organic compound ebselen in the absence of glutathione, Biochem. Pharmacol., 48, 65, 10.1016/0006-2952(94)90224-0 Cotgreave, 1989, Studies on the anti-inflammatory activity of ebselen: Ebselen interferes with granulocyte oxidative burst by dual inhibition of NADPH oxidase and protein kinase C, Biochem. Pharmacol., 38, 649, 10.1016/0006-2952(89)90211-6 Tabuchi, 1995, Ebselen, a selenoorganic compound, protects against ethanol-induced murine gastric mucosal injury in both in vivo and in vitro systems, Eur. J. Pharmacol., 272, 195, 10.1016/0014-2999(95)90819-U Zembowicz, 1993, Inhibition of endothelial nitric oxide synthase by ebselen: Prevention by thiols suggests the inactivation by ebselen of a critical thiol essetial for the catalytic activity of nitric oxide synthase, J. Pharmacol. Exp. Ther., 267, 1112 Nikawa, 1994, Interaction of albumin-bound ebselen with rat liver glutathione S-transferase and microsomal proteins, Biochem. Mol. Biol. Int., 32, 291 Schewe, 1995, Molecular actions of ebselen: An anti-inflammatory antioxidant, Gen. Pharmacol., 26, 1153, 10.1016/0306-3623(95)00003-J Oates, 1988, Studies on the mechanism of ethanol-induced gastric damage in rats, Gastroenterology, 94, 10, 10.1016/0016-5085(88)90604-X Lee, 1992, Gender differences in ethanol oxidation and injury in tha rat stomach, Alcohol., 9, 421, 10.1016/0741-8329(92)90042-9 Mutoh, 1990, Role of oxygen radicals in ethanol-induced damage to cultered gastric mucosal cells, Am. J. Physiol., 258, G603 Matsumoto, 1993, Role of polymorphonuclear leucocytes and oxygen-derived free radicals in the formation of gastric lesions induced by HCl/ethanol, and a possible mechanism of protection by antiulcer polysaccharide, J. Pharm. Pharmacol., 45, 535, 10.1111/j.2042-7158.1993.tb05594.x Hijioka, 1991, Ethanol-induced disturbance of hepatic microcirculation and hepatic hypoxia, Biochem. Pharmacol., 41, 1551, 10.1016/0006-2952(91)90153-V Schmidt, 1987, The protective effects of a prostaglandin without antisecretory properties against ethanol-induced injury in the rat stomach: A histologic study, His. Histopathol., 2, 173 Nakao, 1965, Highly specific sodium-potassium-associated adenosine triphosphate from various tissues of rabbit, Biochem. Biophys. Res. Commun., 19, 755, 10.1016/0006-291X(65)90323-2 Tausski, 1953, A micro colorimetric method for determination of inorganic phosphorus, J. Biol. Chem., 202, 675, 10.1016/S0021-9258(18)66180-0 Lowry, 1951, Protein measurement with folin phenol reagent, J. Biol. Chem., 193, 265, 10.1016/S0021-9258(19)52451-6 Beauchamp, 1971, Superoxide dismutase: improved assays and applicable to acrylamide gels, Anal. Biochem., 44, 276, 10.1016/0003-2697(71)90370-8 Aruoma, 1994, Deoxyribose assay for detecting hydroxyl radicals, Methods in Enzymology, 233, 57, 10.1016/S0076-6879(94)33008-5 Beil, 1990, Interaction of the antiinflammatory seleno-organic compound ebselen with acid secretion in isolated parietal cells and gastric H+/K+-AT-Pase, Biochem.Pharmacol., 40, 1997, 10.1016/0006-2952(90)90229-E Julkunen, 1985, First pass metabolism of ethanol- a gastrointestinal barrier against the systemic toxicity of ethanol, Life Sci., 37, 567, 10.1016/0024-3205(85)90470-9 Sies, 1997, Glutathione Peroxidase protects against peroxynitritemediated oxidations, J. Biol. Chem., 272, 27812, 10.1074/jbc.272.44.27812 Crow, 1995, Sensitivity of the essential zinc-thiolate moiety of yeast alcohol dehydrogenase to hypochlorite and peroxynitrite, Biochemistry, 34, 3544, 10.1021/bi00011a008 Szelenyi, 1988, Possible role of oxygen free radicals in ethanol-induced gastric mucosal damage in rats, Dig. Dis. Sci., 33, 865, 10.1007/BF01550977 Ligumski, 1995, Antioxidants inhibit ethanol-induced gastric injury in the rat, Scand. J. Gastroenterol., 30, 854, 10.3109/00365529509101591 Loguercio, 1993, Glutathione prevents ethanol induced gastric mucosal damage and depletion of sulfhydryl compounds in humans, Gut, 34, 161, 10.1136/gut.34.2.161 Mayorino, 1992, Antioxidant effect of ebselen (PZ 51): Peroxidase mimetic activity on phospholipid and cholesterol hydroperoxides vs free radical scavenger activity, Arch. Biochem. Biophys., 295, 404, 10.1016/0003-9861(92)90534-4